Journal: Critical Care and Resuscitation

Article Title: An in-vitro study to characterise analytical interference caused by sodium ascorbate with point-of-care measurement of lactate and glucose

doi: 10.1016/j.ccrj.2026.100174

Figure Lengend Snippet: Measurements for lactate and blood glucose across devices.

Article Snippet: Baseline and spiked blood samples were immediately analysed at the bedside with several POC devices, based on availability, including the RAPIDPoint® 500 Blood gas system (Siemens HealthCare, Erlangen, Germany), Epoc® Blood analysis system (Siemens HeathCare, Erlangen, Germany), Radiometer ABL800 blood gas analyser (Radiometer, Copenhagen, Denmark), StatProfile® Prime Plus blood gas analyser (Nova Biomedical, Waltham, USA), i-STAT 1® blood analyser (Abbott Laboratories, North Chicago, USA), HemoCue® Glucose 201 (HemoCue, Angelholm, Sweden), FreeStyle Optium Neo (Abbott, Illinois, USA), StatStrip Xpress® lactate system (Nova Biomedical, Waltham, USA) and the StatStrip Xpress® glucose meter (Nova Biomedical, Waltham, USA) ( ).

Techniques:

Journal: Critical Care and Resuscitation

Article Title: An in-vitro study to characterise analytical interference caused by sodium ascorbate with point-of-care measurement of lactate and glucose

doi: 10.1016/j.ccrj.2026.100174

Figure Lengend Snippet: Measured lactate at baseline and target ascorbate levels for ABL800, Prime Plus, Roche colorimetric (SA Pathology), Epoc, StatStrip Xpress, and i-STAT 1 blood analyser (in series order). Data are median [IQR].

Article Snippet: Baseline and spiked blood samples were immediately analysed at the bedside with several POC devices, based on availability, including the RAPIDPoint® 500 Blood gas system (Siemens HealthCare, Erlangen, Germany), Epoc® Blood analysis system (Siemens HeathCare, Erlangen, Germany), Radiometer ABL800 blood gas analyser (Radiometer, Copenhagen, Denmark), StatProfile® Prime Plus blood gas analyser (Nova Biomedical, Waltham, USA), i-STAT 1® blood analyser (Abbott Laboratories, North Chicago, USA), HemoCue® Glucose 201 (HemoCue, Angelholm, Sweden), FreeStyle Optium Neo (Abbott, Illinois, USA), StatStrip Xpress® lactate system (Nova Biomedical, Waltham, USA) and the StatStrip Xpress® glucose meter (Nova Biomedical, Waltham, USA) ( ).

Techniques:

Journal: Critical Care and Resuscitation

Article Title: An in-vitro study to characterise analytical interference caused by sodium ascorbate with point-of-care measurement of lactate and glucose

doi: 10.1016/j.ccrj.2026.100174

Figure Lengend Snippet: Measured plasma lactate at baseline and target ascorbate levels for devices Roche colorimetric (SA Pathology; open circles), Radiometer ABL800 blood gas analyser (squares) and StatProfile Prime Plus blood gas analyser (diamonds). Data are mean (95% CI) estimated by GEE model; device × target interaction effect p<0.0001, with between-device differences at all target levels p<0.05.

Article Snippet: Baseline and spiked blood samples were immediately analysed at the bedside with several POC devices, based on availability, including the RAPIDPoint® 500 Blood gas system (Siemens HealthCare, Erlangen, Germany), Epoc® Blood analysis system (Siemens HeathCare, Erlangen, Germany), Radiometer ABL800 blood gas analyser (Radiometer, Copenhagen, Denmark), StatProfile® Prime Plus blood gas analyser (Nova Biomedical, Waltham, USA), i-STAT 1® blood analyser (Abbott Laboratories, North Chicago, USA), HemoCue® Glucose 201 (HemoCue, Angelholm, Sweden), FreeStyle Optium Neo (Abbott, Illinois, USA), StatStrip Xpress® lactate system (Nova Biomedical, Waltham, USA) and the StatStrip Xpress® glucose meter (Nova Biomedical, Waltham, USA) ( ).

Techniques: Clinical Proteomics

Journal: International Dental Journal

Article Title: Chemokine-Like Receptor 1 Knockdown Suppresses Oral Squamous Cell Carcinoma Progression by Reducing Oxidative Phosphorylation

doi: 10.1016/j.identj.2026.109479

Figure Lengend Snippet: CMKLR1 knockdown suppresses mitochondrial OXPHOS in OSCC cells. (A) Volcano plot of DEPs in CMKLR1-knockdown and control Cal-27 cells, depicting upregulated proteins (red), downregulated proteins (blue), and nonsignificant proteins (gray). (B) Heatmap of the top DEPs identified through proteomic analysis. (C) Subcellular localization pie chart of DEPs, revealing a large proportion localized to mitochondria. (D, E) GO and KEGG pathway enrichment analyses of DEPs, highlighting enrichment in OXPHOS-related processes. (F) Gene set enrichment analysis demonstrating the significant downregulation of OXPHOS in CMKLR1-silenced cells. (G) Seahorse XF analysis of mitochondrial respiration indicating a reduced OCR in CMKLR1-knockdown OSCC cells. (H) Quantification of basal respiration, ATP production, maximal respiration, and spare respiratory capacity in CMKLR1-knockdown cells. (I) Western blot analysis of representative OXPHOS complex subunits (CI-NDUFB8, CII-SDHB, CIII-UQCRC1, CIV-MTCO2, and CV-ATP5A1), with β-actin as loading control. (J) Representative MitoTracker images and quantification of fluorescence intensity (MitoTracker Red, scale bar = 20 μm). * P < .05; ** P < .01; *** P < .001.

Article Snippet: All proteomic analyses were conducted by GeneChem (Shanghai, China).

Techniques: Knockdown, Control, Western Blot, Fluorescence