wrw4 (Alomone Labs)
Alomone Labs is a verified supplier 
Alomone Labs manufactures this product 
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Name:
WRW4
Description:
WRW4 is a selective and potent antagonist of the Formylpeptide receptor FPR2
Catalog Number:
GPW-110
Price:
67.0
Category:
Peptide
Source:
Synthetic peptide
Applications:
0
Purity:
>98% (HPLC)
Size:
0 5 mg
Format:
Lyophilized powder.
Formula:
C61H65N15O6
Molecular Weight:
1104.3 Da.
Molecule Name:
WRW4, WRW4, Formyl Peptide Receptor - Like 1 (FPRL1) Antagonist
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Structured Review
Alomone Labs
wrw4
WRW4 is a selective and potent antagonist of the Formylpeptide receptor FPR2
https://www.bioz.com/result/wrw4/product/Alomone Labs
Average 94 stars, based on 1 article reviews
Price from $9.99 to $1999.99
WRW4 is a selective and potent antagonist of the Formylpeptide receptor FPR2
https://www.bioz.com/result/wrw4/product/Alomone Labs
Average 94 stars, based on 1 article reviews
Price from $9.99 to $1999.99
wrw4 - by Bioz Stars,
2021-09
94/100 stars
Images
1) Product Images from "Inhibiting PSMα-induced neutrophil necroptosis protects mice with MRSA pneumonia by blocking the agr system"
Article Title: Inhibiting PSMα-induced neutrophil necroptosis protects mice with MRSA pneumonia by blocking the agr system
Journal: Cell Death & Disease
doi: 10.1038/s41419-018-0398-z
Figure Legend Snippet: PSMα1-induced neutrophil necroptosis was blocked by WRW4 or anti-TNFα. a, c Neutrophil were treated with PBS or TNFα neutralizing antibody at indicated concentrations for 1 h prior to the incubation with 1 μM PSMα1 for 1 h. The release of LDH was detected ( n = 6) and the level of pMLKL, MLKL and β-actin in neutrophil were detected by western blot ( n = 3). b, d, e Neutrophil were treated with PBS or WRW4 at indicated concentrations for 1 h prior to the incubation with 1 μM PSMα1 for 1 h. The release of LDH was detected ( n = 6), the level of pMLKL, MLKL and β-actin in neutrophil were detected by western blot ( n = 3), and the level of TNFα was detected by ELISA assay ( n = 8). Data were shown as mean ± SE (a, b, e). * P
Techniques Used: Incubation, Western Blot, Enzyme-linked Immunosorbent Assay
2) Product Images from "Inhibiting PSMα-induced neutrophil necroptosis protects mice with MRSA pneumonia by blocking the agr system"
Article Title: Inhibiting PSMα-induced neutrophil necroptosis protects mice with MRSA pneumonia by blocking the agr system
Journal: Cell Death & Disease
doi: 10.1038/s41419-018-0398-z
Figure Legend Snippet: PSMα1-induced neutrophil necroptosis was blocked by WRW4 or anti-TNFα. a, c Neutrophil were treated with PBS or TNFα neutralizing antibody at indicated concentrations for 1 h prior to the incubation with 1 μM PSMα1 for 1 h. The release of LDH was detected ( n = 6) and the level of pMLKL, MLKL and β-actin in neutrophil were detected by western blot ( n = 3). b, d, e Neutrophil were treated with PBS or WRW4 at indicated concentrations for 1 h prior to the incubation with 1 μM PSMα1 for 1 h. The release of LDH was detected ( n = 6), the level of pMLKL, MLKL and β-actin in neutrophil were detected by western blot ( n = 3), and the level of TNFα was detected by ELISA assay ( n = 8). Data were shown as mean ± SE (a, b, e). * P
Techniques Used: Incubation, Western Blot, Enzyme-linked Immunosorbent Assay
Related Articles
other:Article Title: The N-Formyl Peptide Receptor 2 (FPR2) Agonist MR-39 Exhibits Anti-Inflammatory Activity in LPS-Stimulated Organotypic Hippocampal Cultures Article Snippet: The Article Title: Novel Ureidopropanamide Based N-Formyl Peptide Receptor 2 (FPR2) Agonists with Potential Application for Central Nervous System Disorders Characterized by Neuroinflammation Article Snippet: Additionally, in experiments where the secretion of NO or cytokines were measured, the Cell Culture:Article Title: Inhibiting PSMα-induced neutrophil necroptosis protects mice with MRSA pneumonia by blocking the agr system Article Snippet: .. Neutrophil cells were respectively stimulated with PSM peptide for 1 h at 37 °C and then centrifugated (1000 rpm, 10 min) after pretreated with or without NSA, Nec, Sequencing:Article Title: Bacterial lipopolysaccharide and antimicrobial LL-37 enhance ICAM-1 expression and NF-κB p65 phosphorylation in senescent endothelial cells Article Snippet: .. The Staining:Article Title: The Annexin A1 Receptor FPR2 Regulates the Endosomal Export of Influenza Virus Article Snippet: .. Reagents Cells and VirusesThe following reagents were used in this study: antiviral M2 protein (Santa Cruz, Heidelberg, Germany), Alexa Fluor secondary antibodies (Life Technologies, Villebon-sur-Yvette, France), DAPI (4′,6′-diamidino-2-phenylindole, Sigma-Aldrich, Darmstadt, Germany), phalloidin (Invitrogen, Villebon-sur-Yvette, France), purple crystal staining (Sigma, Darmstadt, Germany), Article Title: The Annexin A1 Receptor FPR2 Regulates the Endosomal Export of Influenza Virus Article Snippet: .. The following reagents were used in this study: antiviral M2 protein (Santa Cruz, Heidelberg, Germany), Alexa Fluor secondary antibodies (Life Technologies, Villebon-sur-Yvette, France), DAPI (4′,6′-diamidino-2-phenylindole, Sigma-Aldrich, Darmstadt, Germany), phalloidin (Invitrogen, Villebon-sur-Yvette, France), purple crystal staining (Sigma, Darmstadt, Germany), |