4 9 anhydrotetrodotoxin  (Alomone Labs)


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    Alomone Labs 4 9 anhydrotetrodotoxin
    Effect of 4,9-an-TTX on  I Na  is greatest in mature PZ calyces.  (A)  Reduction of  I Na  in response to perfusion of 100 nM 4,9-ah-TTX in a representative PZ calyx (P31) and CZ calyx-only fiber (P27) in crista slice in response to a voltage step from –130 to –50 mV. External solution was 0 K +  HEPES.  (B)  Mean response to 100 nM 4,9-ah-TTX in mature CZ ( ; P20–27), PZ (o; P22–31) and immature calyces (Δ; P5–14) and response in mature PZ calyces ( ; P22–29) to 200 nM 4,9-ah-TTX are shown. Numbers above plots indicate number of cells for each group. Electrode solution was Cs + -based and external solution was L-15 or 0 K +  HEPES with either 80 mM Na +  or 150 mM Na + .
    4 9 Anhydrotetrodotoxin, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/4 9 anhydrotetrodotoxin/product/Alomone Labs
    Average 93 stars, based on 5 article reviews
    Price from $9.99 to $1999.99
    4 9 anhydrotetrodotoxin - by Bioz Stars, 2022-11
    93/100 stars

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    1) Product Images from "Regional and Developmental Differences in Na+ Currents in Vestibular Primary Afferent Neurons"

    Article Title: Regional and Developmental Differences in Na+ Currents in Vestibular Primary Afferent Neurons

    Journal: Frontiers in Cellular Neuroscience

    doi: 10.3389/fncel.2018.00423

    Effect of 4,9-an-TTX on  I Na  is greatest in mature PZ calyces.  (A)  Reduction of  I Na  in response to perfusion of 100 nM 4,9-ah-TTX in a representative PZ calyx (P31) and CZ calyx-only fiber (P27) in crista slice in response to a voltage step from –130 to –50 mV. External solution was 0 K +  HEPES.  (B)  Mean response to 100 nM 4,9-ah-TTX in mature CZ ( ; P20–27), PZ (o; P22–31) and immature calyces (Δ; P5–14) and response in mature PZ calyces ( ; P22–29) to 200 nM 4,9-ah-TTX are shown. Numbers above plots indicate number of cells for each group. Electrode solution was Cs + -based and external solution was L-15 or 0 K +  HEPES with either 80 mM Na +  or 150 mM Na + .
    Figure Legend Snippet: Effect of 4,9-an-TTX on I Na is greatest in mature PZ calyces. (A) Reduction of I Na in response to perfusion of 100 nM 4,9-ah-TTX in a representative PZ calyx (P31) and CZ calyx-only fiber (P27) in crista slice in response to a voltage step from –130 to –50 mV. External solution was 0 K + HEPES. (B) Mean response to 100 nM 4,9-ah-TTX in mature CZ ( ; P20–27), PZ (o; P22–31) and immature calyces (Δ; P5–14) and response in mature PZ calyces ( ; P22–29) to 200 nM 4,9-ah-TTX are shown. Numbers above plots indicate number of cells for each group. Electrode solution was Cs + -based and external solution was L-15 or 0 K + HEPES with either 80 mM Na + or 150 mM Na + .

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    Alomone Labs 4 9 anhydrotetrodotoxin
    Effect of 4,9-an-TTX on  I Na  is greatest in mature PZ calyces.  (A)  Reduction of  I Na  in response to perfusion of 100 nM 4,9-ah-TTX in a representative PZ calyx (P31) and CZ calyx-only fiber (P27) in crista slice in response to a voltage step from –130 to –50 mV. External solution was 0 K +  HEPES.  (B)  Mean response to 100 nM 4,9-ah-TTX in mature CZ ( ; P20–27), PZ (o; P22–31) and immature calyces (Δ; P5–14) and response in mature PZ calyces ( ; P22–29) to 200 nM 4,9-ah-TTX are shown. Numbers above plots indicate number of cells for each group. Electrode solution was Cs + -based and external solution was L-15 or 0 K +  HEPES with either 80 mM Na +  or 150 mM Na + .
    4 9 Anhydrotetrodotoxin, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/4 9 anhydrotetrodotoxin/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    4 9 anhydrotetrodotoxin - by Bioz Stars, 2022-11
    93/100 stars
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    Effect of 4,9-an-TTX on  I Na  is greatest in mature PZ calyces.  (A)  Reduction of  I Na  in response to perfusion of 100 nM 4,9-ah-TTX in a representative PZ calyx (P31) and CZ calyx-only fiber (P27) in crista slice in response to a voltage step from –130 to –50 mV. External solution was 0 K +  HEPES.  (B)  Mean response to 100 nM 4,9-ah-TTX in mature CZ ( ; P20–27), PZ (o; P22–31) and immature calyces (Δ; P5–14) and response in mature PZ calyces ( ; P22–29) to 200 nM 4,9-ah-TTX are shown. Numbers above plots indicate number of cells for each group. Electrode solution was Cs + -based and external solution was L-15 or 0 K +  HEPES with either 80 mM Na +  or 150 mM Na + .

    Journal: Frontiers in Cellular Neuroscience

    Article Title: Regional and Developmental Differences in Na+ Currents in Vestibular Primary Afferent Neurons

    doi: 10.3389/fncel.2018.00423

    Figure Lengend Snippet: Effect of 4,9-an-TTX on I Na is greatest in mature PZ calyces. (A) Reduction of I Na in response to perfusion of 100 nM 4,9-ah-TTX in a representative PZ calyx (P31) and CZ calyx-only fiber (P27) in crista slice in response to a voltage step from –130 to –50 mV. External solution was 0 K + HEPES. (B) Mean response to 100 nM 4,9-ah-TTX in mature CZ ( ; P20–27), PZ (o; P22–31) and immature calyces (Δ; P5–14) and response in mature PZ calyces ( ; P22–29) to 200 nM 4,9-ah-TTX are shown. Numbers above plots indicate number of cells for each group. Electrode solution was Cs + -based and external solution was L-15 or 0 K + HEPES with either 80 mM Na + or 150 mM Na + .

    Article Snippet: Stock solutions of 4,9-anhydrotetrodotoxin (4,9-ah-TTX, Alomone Labs) were prepared in ethanol, stored at −20°C and used within 3 weeks.

    Techniques: