t channel antagonist tta p2  (Alomone Labs)


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    Alomone Labs t channel antagonist tta p2
    Pretreatment <t>TTA-P2</t> reduces latency to seizure during alcohol withdrawal. Animals in alcohol withdrawal were treated with 10, 20, 40 mg/kg TTA-P2 or saline. Thirty minutes later, all animals were injected with a high dose of PTZ. Pretreatment with 40 mg/kg TTA-P2 significantly increased the latency to seizure.
    T Channel Antagonist Tta P2, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/t channel antagonist tta p2/product/Alomone Labs
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    t channel antagonist tta p2 - by Bioz Stars, 2021-09
    86/100 stars

    Images

    1) Product Images from "Selective Blockade of T-Type Ca2+ Channels is Protective Against Alcohol-Withdrawal Induced Seizure and Mortality"

    Article Title: Selective Blockade of T-Type Ca2+ Channels is Protective Against Alcohol-Withdrawal Induced Seizure and Mortality

    Journal: Alcohol and Alcoholism (Oxford, Oxfordshire)

    doi: 10.1093/alcalc/agy042

    Pretreatment TTA-P2 reduces latency to seizure during alcohol withdrawal. Animals in alcohol withdrawal were treated with 10, 20, 40 mg/kg TTA-P2 or saline. Thirty minutes later, all animals were injected with a high dose of PTZ. Pretreatment with 40 mg/kg TTA-P2 significantly increased the latency to seizure.
    Figure Legend Snippet: Pretreatment TTA-P2 reduces latency to seizure during alcohol withdrawal. Animals in alcohol withdrawal were treated with 10, 20, 40 mg/kg TTA-P2 or saline. Thirty minutes later, all animals were injected with a high dose of PTZ. Pretreatment with 40 mg/kg TTA-P2 significantly increased the latency to seizure.

    Techniques Used: Injection

    Pretreatment with TTA-P2 is protective against and mortality during alcohol withdrawal. Animals in alcohol withdrawal were treated with 10, 20, 40 mg/kg TTA-P2 or saline. Thirty minutes later, all animals were injected with a high dose of PTZ. Animals that were pretreated with TTA-P2 had higher survival rates following treatment with PTZ ( a ). Pretreatment with 40 mg/kg TTA-P2 significantly increased latency to death ( b ).
    Figure Legend Snippet: Pretreatment with TTA-P2 is protective against and mortality during alcohol withdrawal. Animals in alcohol withdrawal were treated with 10, 20, 40 mg/kg TTA-P2 or saline. Thirty minutes later, all animals were injected with a high dose of PTZ. Animals that were pretreated with TTA-P2 had higher survival rates following treatment with PTZ ( a ). Pretreatment with 40 mg/kg TTA-P2 significantly increased latency to death ( b ).

    Techniques Used: Injection

    Related Articles

    other:

    Article Title: The role of T‐type calcium channels in the subiculum: to burst or not to burst?
    Article Snippet: These findings were confirmed using 5 μ m TTA‐P2 ( n = 5 neurons).

    Mouse Assay:

    Article Title: Selective Blockade of T-Type Ca2+ Channels is Protective Against Alcohol-Withdrawal Induced Seizure and Mortality
    Article Snippet: .. Approximately 6 h into the 4th WD period, mice were treated with the T-channel antagonist TTA-P2 (10, 20 or 40 mg/kg intraperitoneal; Alomone Labs, Jerusalem, Israel) or saline. ..

    Concentration Assay:

    Article Title: The role of T‐type calcium channels in the subiculum: to burst or not to burst?
    Article Snippet: .. The lower concentration of TTA‐P2 (5 μ m ) was used to exclude possible off‐target effects of this selective T‐channel antagonist, especially those concerning CaV 2.3 R‐type calcium channels (Choe et al .). ..

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    Alomone Labs t channel antagonist tta p2
    Pretreatment <t>TTA-P2</t> reduces latency to seizure during alcohol withdrawal. Animals in alcohol withdrawal were treated with 10, 20, 40 mg/kg TTA-P2 or saline. Thirty minutes later, all animals were injected with a high dose of PTZ. Pretreatment with 40 mg/kg TTA-P2 significantly increased the latency to seizure.
    T Channel Antagonist Tta P2, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/t channel antagonist tta p2/product/Alomone Labs
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    t channel antagonist tta p2 - by Bioz Stars, 2021-09
    86/100 stars
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    Pretreatment TTA-P2 reduces latency to seizure during alcohol withdrawal. Animals in alcohol withdrawal were treated with 10, 20, 40 mg/kg TTA-P2 or saline. Thirty minutes later, all animals were injected with a high dose of PTZ. Pretreatment with 40 mg/kg TTA-P2 significantly increased the latency to seizure.

    Journal: Alcohol and Alcoholism (Oxford, Oxfordshire)

    Article Title: Selective Blockade of T-Type Ca2+ Channels is Protective Against Alcohol-Withdrawal Induced Seizure and Mortality

    doi: 10.1093/alcalc/agy042

    Figure Lengend Snippet: Pretreatment TTA-P2 reduces latency to seizure during alcohol withdrawal. Animals in alcohol withdrawal were treated with 10, 20, 40 mg/kg TTA-P2 or saline. Thirty minutes later, all animals were injected with a high dose of PTZ. Pretreatment with 40 mg/kg TTA-P2 significantly increased the latency to seizure.

    Article Snippet: Approximately 6 h into the 4th WD period, mice were treated with the T-channel antagonist TTA-P2 (10, 20 or 40 mg/kg intraperitoneal; Alomone Labs, Jerusalem, Israel) or saline.

    Techniques: Injection

    Pretreatment with TTA-P2 is protective against and mortality during alcohol withdrawal. Animals in alcohol withdrawal were treated with 10, 20, 40 mg/kg TTA-P2 or saline. Thirty minutes later, all animals were injected with a high dose of PTZ. Animals that were pretreated with TTA-P2 had higher survival rates following treatment with PTZ ( a ). Pretreatment with 40 mg/kg TTA-P2 significantly increased latency to death ( b ).

    Journal: Alcohol and Alcoholism (Oxford, Oxfordshire)

    Article Title: Selective Blockade of T-Type Ca2+ Channels is Protective Against Alcohol-Withdrawal Induced Seizure and Mortality

    doi: 10.1093/alcalc/agy042

    Figure Lengend Snippet: Pretreatment with TTA-P2 is protective against and mortality during alcohol withdrawal. Animals in alcohol withdrawal were treated with 10, 20, 40 mg/kg TTA-P2 or saline. Thirty minutes later, all animals were injected with a high dose of PTZ. Animals that were pretreated with TTA-P2 had higher survival rates following treatment with PTZ ( a ). Pretreatment with 40 mg/kg TTA-P2 significantly increased latency to death ( b ).

    Article Snippet: Approximately 6 h into the 4th WD period, mice were treated with the T-channel antagonist TTA-P2 (10, 20 or 40 mg/kg intraperitoneal; Alomone Labs, Jerusalem, Israel) or saline.

    Techniques: Injection