kt5823  (Alomone Labs)


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    Alomone Labs kt5823
    Inhibition of PKG prevented the proliferation of SVZ cells stimulated by PDE5 inhibitors. Cell proliferation following treatment with 1 μ M <t>KT5823</t> and 1 μ M T0156 (a, d), 1 μ M sildenafil (b, e), or 10 μ M zaprinast (c, f) was assessed by incorporation of EdU and evaluated by flow cytometry, following 6 h or 24 h of treatment. Data are expressed as means ± SEM of at least 4 independent experiments. One-way ANOVA (Bonferroni's post-test), * P
    Kt5823, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 85/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/kt5823/product/Alomone Labs
    Average 85 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    kt5823 - by Bioz Stars, 2022-05
    85/100 stars

    Images

    1) Product Images from "Stimulation of Neural Stem Cell Proliferation by Inhibition of Phosphodiesterase 5"

    Article Title: Stimulation of Neural Stem Cell Proliferation by Inhibition of Phosphodiesterase 5

    Journal: Stem Cells International

    doi: 10.1155/2014/878397

    Inhibition of PKG prevented the proliferation of SVZ cells stimulated by PDE5 inhibitors. Cell proliferation following treatment with 1 μ M KT5823 and 1 μ M T0156 (a, d), 1 μ M sildenafil (b, e), or 10 μ M zaprinast (c, f) was assessed by incorporation of EdU and evaluated by flow cytometry, following 6 h or 24 h of treatment. Data are expressed as means ± SEM of at least 4 independent experiments. One-way ANOVA (Bonferroni's post-test), * P
    Figure Legend Snippet: Inhibition of PKG prevented the proliferation of SVZ cells stimulated by PDE5 inhibitors. Cell proliferation following treatment with 1 μ M KT5823 and 1 μ M T0156 (a, d), 1 μ M sildenafil (b, e), or 10 μ M zaprinast (c, f) was assessed by incorporation of EdU and evaluated by flow cytometry, following 6 h or 24 h of treatment. Data are expressed as means ± SEM of at least 4 independent experiments. One-way ANOVA (Bonferroni's post-test), * P

    Techniques Used: Inhibition, Flow Cytometry, Cytometry

    Activation of sGC stimulates proliferation of NSC, increases ERK1/2 phosphorylation, and decreases p27 Kip1 levels. Cell proliferation following treatment with 20 μ M YC-1 (a) for 24 h was assessed by the incorporation of EdU and analyzed by flow cytometry. Levels of phospho-ERK1/2 following treatment with 20 μ M YC-1 (b) or YC-1 plus 1 μ M KT5823 (c) and p27 Kip1 levels following treatment with YC-1 (d) or YC-1 plus 1 μ M U0126 (e) or KT5823 (f) for 2 h were assessed by Western blot. Representative images are shown. Data are expressed as means ± SEM of at least 4 independent experiments. (a), (b), and (d) two-tailed t -test, * P
    Figure Legend Snippet: Activation of sGC stimulates proliferation of NSC, increases ERK1/2 phosphorylation, and decreases p27 Kip1 levels. Cell proliferation following treatment with 20 μ M YC-1 (a) for 24 h was assessed by the incorporation of EdU and analyzed by flow cytometry. Levels of phospho-ERK1/2 following treatment with 20 μ M YC-1 (b) or YC-1 plus 1 μ M KT5823 (c) and p27 Kip1 levels following treatment with YC-1 (d) or YC-1 plus 1 μ M U0126 (e) or KT5823 (f) for 2 h were assessed by Western blot. Representative images are shown. Data are expressed as means ± SEM of at least 4 independent experiments. (a), (b), and (d) two-tailed t -test, * P

    Techniques Used: Activation Assay, Flow Cytometry, Cytometry, Western Blot, Two Tailed Test

    Inhibition of PKG did not prevent the decrease of p27 Kip1 levels by T0156. p27 Kip1 levels following treatment with 1 μ M KT5823 and 1 μ M T0156 (a), 1 μ M sildenafil (b), or 10 μ M zaprinast (c) for 2 h were assessed by Western blot. Representative images are shown. Data are expressed as means ± SEM of at least 4 independent experiments. One-way ANOVA (Bonferroni's post-test), * P
    Figure Legend Snippet: Inhibition of PKG did not prevent the decrease of p27 Kip1 levels by T0156. p27 Kip1 levels following treatment with 1 μ M KT5823 and 1 μ M T0156 (a), 1 μ M sildenafil (b), or 10 μ M zaprinast (c) for 2 h were assessed by Western blot. Representative images are shown. Data are expressed as means ± SEM of at least 4 independent experiments. One-way ANOVA (Bonferroni's post-test), * P

    Techniques Used: Inhibition, Western Blot

    Inhibition of PKG prevented the phosphorylation of ERK1/2 by treatment with T0156 or zaprinast. Levels of phospho-ERK1/2 following treatment with 1 μ M KT5823 and 1 μ M T0156 (a), 1 μ M sildenafil (b), and 10 μ M zaprinast (c) for 2 h were assessed by Western blot. Representative images are shown. Data are expressed as means ± SEM of at least 4 independent experiments. One-way ANOVA (Bonferroni's post-test), * P
    Figure Legend Snippet: Inhibition of PKG prevented the phosphorylation of ERK1/2 by treatment with T0156 or zaprinast. Levels of phospho-ERK1/2 following treatment with 1 μ M KT5823 and 1 μ M T0156 (a), 1 μ M sildenafil (b), and 10 μ M zaprinast (c) for 2 h were assessed by Western blot. Representative images are shown. Data are expressed as means ± SEM of at least 4 independent experiments. One-way ANOVA (Bonferroni's post-test), * P

    Techniques Used: Inhibition, Western Blot

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    • kt5823  (Alomone Labs)
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    Alomone Labs kt5823
    Inhibition of PKG prevented the proliferation of SVZ cells stimulated by PDE5 inhibitors. Cell proliferation following treatment with 1 μ M <t>KT5823</t> and 1 μ M T0156 (a, d), 1 μ M sildenafil (b, e), or 10 μ M zaprinast (c, f) was assessed by incorporation of EdU and evaluated by flow cytometry, following 6 h or 24 h of treatment. Data are expressed as means ± SEM of at least 4 independent experiments. One-way ANOVA (Bonferroni's post-test), * P
    Kt5823, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 85/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/kt5823/product/Alomone Labs
    Average 85 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    kt5823 - by Bioz Stars, 2022-05
    85/100 stars
    		  Buy from Supplier

    Image Search Results


    Inhibition of PKG prevented the proliferation of SVZ cells stimulated by PDE5 inhibitors. Cell proliferation following treatment with 1 μ M KT5823 and 1 μ M T0156 (a, d), 1 μ M sildenafil (b, e), or 10 μ M zaprinast (c, f) was assessed by incorporation of EdU and evaluated by flow cytometry, following 6 h or 24 h of treatment. Data are expressed as means ± SEM of at least 4 independent experiments. One-way ANOVA (Bonferroni's post-test), * P

    Journal: Stem Cells International

    Article Title: Stimulation of Neural Stem Cell Proliferation by Inhibition of Phosphodiesterase 5

    doi: 10.1155/2014/878397

    Figure Lengend Snippet: Inhibition of PKG prevented the proliferation of SVZ cells stimulated by PDE5 inhibitors. Cell proliferation following treatment with 1 μ M KT5823 and 1 μ M T0156 (a, d), 1 μ M sildenafil (b, e), or 10 μ M zaprinast (c, f) was assessed by incorporation of EdU and evaluated by flow cytometry, following 6 h or 24 h of treatment. Data are expressed as means ± SEM of at least 4 independent experiments. One-way ANOVA (Bonferroni's post-test), * P

    Article Snippet: KT5823 was obtained from Alomone Labs (Jerusalem, Israel) and 3-(5′-Hydroxymethyl-2′-furyl)-1-benzylindazole (YC-1) from Santa Cruz Biotechnology (Santa Cruz, CA, USA).

    Techniques: Inhibition, Flow Cytometry, Cytometry

    Activation of sGC stimulates proliferation of NSC, increases ERK1/2 phosphorylation, and decreases p27 Kip1 levels. Cell proliferation following treatment with 20 μ M YC-1 (a) for 24 h was assessed by the incorporation of EdU and analyzed by flow cytometry. Levels of phospho-ERK1/2 following treatment with 20 μ M YC-1 (b) or YC-1 plus 1 μ M KT5823 (c) and p27 Kip1 levels following treatment with YC-1 (d) or YC-1 plus 1 μ M U0126 (e) or KT5823 (f) for 2 h were assessed by Western blot. Representative images are shown. Data are expressed as means ± SEM of at least 4 independent experiments. (a), (b), and (d) two-tailed t -test, * P

    Journal: Stem Cells International

    Article Title: Stimulation of Neural Stem Cell Proliferation by Inhibition of Phosphodiesterase 5

    doi: 10.1155/2014/878397

    Figure Lengend Snippet: Activation of sGC stimulates proliferation of NSC, increases ERK1/2 phosphorylation, and decreases p27 Kip1 levels. Cell proliferation following treatment with 20 μ M YC-1 (a) for 24 h was assessed by the incorporation of EdU and analyzed by flow cytometry. Levels of phospho-ERK1/2 following treatment with 20 μ M YC-1 (b) or YC-1 plus 1 μ M KT5823 (c) and p27 Kip1 levels following treatment with YC-1 (d) or YC-1 plus 1 μ M U0126 (e) or KT5823 (f) for 2 h were assessed by Western blot. Representative images are shown. Data are expressed as means ± SEM of at least 4 independent experiments. (a), (b), and (d) two-tailed t -test, * P

    Article Snippet: KT5823 was obtained from Alomone Labs (Jerusalem, Israel) and 3-(5′-Hydroxymethyl-2′-furyl)-1-benzylindazole (YC-1) from Santa Cruz Biotechnology (Santa Cruz, CA, USA).

    Techniques: Activation Assay, Flow Cytometry, Cytometry, Western Blot, Two Tailed Test

    Inhibition of PKG did not prevent the decrease of p27 Kip1 levels by T0156. p27 Kip1 levels following treatment with 1 μ M KT5823 and 1 μ M T0156 (a), 1 μ M sildenafil (b), or 10 μ M zaprinast (c) for 2 h were assessed by Western blot. Representative images are shown. Data are expressed as means ± SEM of at least 4 independent experiments. One-way ANOVA (Bonferroni's post-test), * P

    Journal: Stem Cells International

    Article Title: Stimulation of Neural Stem Cell Proliferation by Inhibition of Phosphodiesterase 5

    doi: 10.1155/2014/878397

    Figure Lengend Snippet: Inhibition of PKG did not prevent the decrease of p27 Kip1 levels by T0156. p27 Kip1 levels following treatment with 1 μ M KT5823 and 1 μ M T0156 (a), 1 μ M sildenafil (b), or 10 μ M zaprinast (c) for 2 h were assessed by Western blot. Representative images are shown. Data are expressed as means ± SEM of at least 4 independent experiments. One-way ANOVA (Bonferroni's post-test), * P

    Article Snippet: KT5823 was obtained from Alomone Labs (Jerusalem, Israel) and 3-(5′-Hydroxymethyl-2′-furyl)-1-benzylindazole (YC-1) from Santa Cruz Biotechnology (Santa Cruz, CA, USA).

    Techniques: Inhibition, Western Blot

    Inhibition of PKG prevented the phosphorylation of ERK1/2 by treatment with T0156 or zaprinast. Levels of phospho-ERK1/2 following treatment with 1 μ M KT5823 and 1 μ M T0156 (a), 1 μ M sildenafil (b), and 10 μ M zaprinast (c) for 2 h were assessed by Western blot. Representative images are shown. Data are expressed as means ± SEM of at least 4 independent experiments. One-way ANOVA (Bonferroni's post-test), * P

    Journal: Stem Cells International

    Article Title: Stimulation of Neural Stem Cell Proliferation by Inhibition of Phosphodiesterase 5

    doi: 10.1155/2014/878397

    Figure Lengend Snippet: Inhibition of PKG prevented the phosphorylation of ERK1/2 by treatment with T0156 or zaprinast. Levels of phospho-ERK1/2 following treatment with 1 μ M KT5823 and 1 μ M T0156 (a), 1 μ M sildenafil (b), and 10 μ M zaprinast (c) for 2 h were assessed by Western blot. Representative images are shown. Data are expressed as means ± SEM of at least 4 independent experiments. One-way ANOVA (Bonferroni's post-test), * P

    Article Snippet: KT5823 was obtained from Alomone Labs (Jerusalem, Israel) and 3-(5′-Hydroxymethyl-2′-furyl)-1-benzylindazole (YC-1) from Santa Cruz Biotechnology (Santa Cruz, CA, USA).

    Techniques: Inhibition, Western Blot