ω conotoxin mviid (Alomone Labs)


Structured Review

ω Conotoxin Mviid, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ω conotoxin mviid/product/Alomone Labs
Average 94 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
1) Product Images from "Activation of Voltage-Gated Na+ Current by GV-58, a Known Activator of CaV Channels"
Article Title: Activation of Voltage-Gated Na+ Current by GV-58, a Known Activator of CaV Channels
Journal: Biomedicines
doi: 10.3390/biomedicines10030721

Figure Legend Snippet: Comparisons of effects of GV-58, GV-58 plus ω-conotoxin MVIID, and GV-58 plus tetrodotoxin (TTX) on the peak amplitude of I Na recorded from GH 3 cells. Cells were immersed in Ca 2+ -free Tyrode’s solution containing 10 mM TEA, and the pipettes used were filled with Cs + -containing solution. Current amplitude was taken at the beginning of the brief depolarizing pulse from −80 to −10 mV. Each bar indicates the mean ± SEM (n = 8 for each bar). Of notice, the peak I Na in GH 3 cells is subject to inhibition by TTX but not by ω-conotoxin MVIID. * Significantly different from control ( p
Techniques Used: Inhibition

Figure Legend Snippet: Effects of GV−58 on spontaneous action potentials (APs) recorded from GH 3 cells. Cells were bathed in normal Tyrode’s solution, and the recording pipettes were filled with K + −containing solution. When whole−cell configuration was established, we switched to the whole−cell current clamp recordings to measure changes in membrane potential, as current was set at zero. ( A ) Representative potential traces achieved in the absence (upper) and presence of 1 μM GV−58 (middle) or 3 μM GV−58 (lower). ( B ) Summary graph demonstrating effect of ω−conotoxin MVIID, GV−58, and GV−58 plus ranolazine (Ran) on the firing frequency of APs in GH 3 cells (mean ± SEM; n = 8). * Significantly different from control ( p
Techniques Used: