trkb fc  (Alomone Labs)


Bioz Verified Symbol Alomone Labs is a verified supplier
Bioz Manufacturer Symbol Alomone Labs manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 91

    Structured Review

    Alomone Labs trkb fc
    Trkb Fc, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/trkb fc/product/Alomone Labs
    Average 91 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    trkb fc - by Bioz Stars, 2023-06
    91/100 stars

    Images

    trkb fc  (Alomone Labs)


    Bioz Verified Symbol Alomone Labs is a verified supplier
    Bioz Manufacturer Symbol Alomone Labs manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 91

    Structured Review

    Alomone Labs trkb fc
    Trkb Fc, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/trkb fc/product/Alomone Labs
    Average 91 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    trkb fc - by Bioz Stars, 2023-06
    91/100 stars

    Images

    recombinant human trkb fc chimera  (Alomone Labs)


    Bioz Verified Symbol Alomone Labs is a verified supplier
    Bioz Manufacturer Symbol Alomone Labs manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 91

    Structured Review

    Alomone Labs recombinant human trkb fc chimera
    Chronic or acute reductions in BDNF lead to increased frequency of spontaneous IPSCs in granule cells involving <t>TrkB</t> receptors. Whole-cell recordings of GABAergic IPSCs in granule cells of the mouse dentate gyrus. A, Spontaneous GABAA receptor-mediated IPSCs recorded in WT and BDNF+/− mice. The action-potential-driven sIPSCs recorded without TTX showed a substantial increase by 65% in BDNF+/− slices. B, Brain slices from WT mice were incubated with either a control antibody (human Fc, 0.74 μg/ml) for 4 h or <t>TrkB-Fc</t> (2.2 μg/ml). In TrkB-Fc, the sIPSC frequency was 200% larger than with human FC. C, Recordings of sIPSCs in control, and in a slice where K-252a (200 nm) was used to inhibit TrkB. The latter slices were incubated with K-252a for 1 h, while control slices were incubated for 1 h with vehicle. K-252a increased the sIPSC frequency by 95%. D, Histogram summarizing the frequency of sIPSCs.
    Recombinant Human Trkb Fc Chimera, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/recombinant human trkb fc chimera/product/Alomone Labs
    Average 91 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    recombinant human trkb fc chimera - by Bioz Stars, 2023-06
    91/100 stars

    Images

    1) Product Images from "Mature BDNF, But Not proBDNF, Reduces Excitability of Fast-Spiking Interneurons in Mouse Dentate Gyrus"

    Article Title: Mature BDNF, But Not proBDNF, Reduces Excitability of Fast-Spiking Interneurons in Mouse Dentate Gyrus

    Journal: The Journal of Neuroscience

    doi: 10.1523/JNEUROSCI.2978-09.2009

    Chronic or acute reductions in BDNF lead to increased frequency of spontaneous IPSCs in granule cells involving TrkB receptors. Whole-cell recordings of GABAergic IPSCs in granule cells of the mouse dentate gyrus. A, Spontaneous GABAA receptor-mediated IPSCs recorded in WT and BDNF+/− mice. The action-potential-driven sIPSCs recorded without TTX showed a substantial increase by 65% in BDNF+/− slices. B, Brain slices from WT mice were incubated with either a control antibody (human Fc, 0.74 μg/ml) for 4 h or TrkB-Fc (2.2 μg/ml). In TrkB-Fc, the sIPSC frequency was 200% larger than with human FC. C, Recordings of sIPSCs in control, and in a slice where K-252a (200 nm) was used to inhibit TrkB. The latter slices were incubated with K-252a for 1 h, while control slices were incubated for 1 h with vehicle. K-252a increased the sIPSC frequency by 95%. D, Histogram summarizing the frequency of sIPSCs.
    Figure Legend Snippet: Chronic or acute reductions in BDNF lead to increased frequency of spontaneous IPSCs in granule cells involving TrkB receptors. Whole-cell recordings of GABAergic IPSCs in granule cells of the mouse dentate gyrus. A, Spontaneous GABAA receptor-mediated IPSCs recorded in WT and BDNF+/− mice. The action-potential-driven sIPSCs recorded without TTX showed a substantial increase by 65% in BDNF+/− slices. B, Brain slices from WT mice were incubated with either a control antibody (human Fc, 0.74 μg/ml) for 4 h or TrkB-Fc (2.2 μg/ml). In TrkB-Fc, the sIPSC frequency was 200% larger than with human FC. C, Recordings of sIPSCs in control, and in a slice where K-252a (200 nm) was used to inhibit TrkB. The latter slices were incubated with K-252a for 1 h, while control slices were incubated for 1 h with vehicle. K-252a increased the sIPSC frequency by 95%. D, Histogram summarizing the frequency of sIPSCs.

    Techniques Used: Incubation

    recombinant human trkb fc chimera  (Alomone Labs)


    Bioz Verified Symbol Alomone Labs is a verified supplier
    Bioz Manufacturer Symbol Alomone Labs manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 91

    Structured Review

    Alomone Labs recombinant human trkb fc chimera
    Recombinant Human Trkb Fc Chimera, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/recombinant human trkb fc chimera/product/Alomone Labs
    Average 91 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    recombinant human trkb fc chimera - by Bioz Stars, 2023-06
    91/100 stars

    Images

    Similar Products

  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 91
    Alomone Labs trkb fc
    Trkb Fc, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/trkb fc/product/Alomone Labs
    Average 91 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    trkb fc - by Bioz Stars, 2023-06
    91/100 stars
      Buy from Supplier

    91
    Alomone Labs recombinant human trkb fc chimera
    Chronic or acute reductions in BDNF lead to increased frequency of spontaneous IPSCs in granule cells involving <t>TrkB</t> receptors. Whole-cell recordings of GABAergic IPSCs in granule cells of the mouse dentate gyrus. A, Spontaneous GABAA receptor-mediated IPSCs recorded in WT and BDNF+/− mice. The action-potential-driven sIPSCs recorded without TTX showed a substantial increase by 65% in BDNF+/− slices. B, Brain slices from WT mice were incubated with either a control antibody (human Fc, 0.74 μg/ml) for 4 h or <t>TrkB-Fc</t> (2.2 μg/ml). In TrkB-Fc, the sIPSC frequency was 200% larger than with human FC. C, Recordings of sIPSCs in control, and in a slice where K-252a (200 nm) was used to inhibit TrkB. The latter slices were incubated with K-252a for 1 h, while control slices were incubated for 1 h with vehicle. K-252a increased the sIPSC frequency by 95%. D, Histogram summarizing the frequency of sIPSCs.
    Recombinant Human Trkb Fc Chimera, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/recombinant human trkb fc chimera/product/Alomone Labs
    Average 91 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    recombinant human trkb fc chimera - by Bioz Stars, 2023-06
    91/100 stars
      Buy from Supplier

    Image Search Results


    Chronic or acute reductions in BDNF lead to increased frequency of spontaneous IPSCs in granule cells involving TrkB receptors. Whole-cell recordings of GABAergic IPSCs in granule cells of the mouse dentate gyrus. A, Spontaneous GABAA receptor-mediated IPSCs recorded in WT and BDNF+/− mice. The action-potential-driven sIPSCs recorded without TTX showed a substantial increase by 65% in BDNF+/− slices. B, Brain slices from WT mice were incubated with either a control antibody (human Fc, 0.74 μg/ml) for 4 h or TrkB-Fc (2.2 μg/ml). In TrkB-Fc, the sIPSC frequency was 200% larger than with human FC. C, Recordings of sIPSCs in control, and in a slice where K-252a (200 nm) was used to inhibit TrkB. The latter slices were incubated with K-252a for 1 h, while control slices were incubated for 1 h with vehicle. K-252a increased the sIPSC frequency by 95%. D, Histogram summarizing the frequency of sIPSCs.

    Journal: The Journal of Neuroscience

    Article Title: Mature BDNF, But Not proBDNF, Reduces Excitability of Fast-Spiking Interneurons in Mouse Dentate Gyrus

    doi: 10.1523/JNEUROSCI.2978-09.2009

    Figure Lengend Snippet: Chronic or acute reductions in BDNF lead to increased frequency of spontaneous IPSCs in granule cells involving TrkB receptors. Whole-cell recordings of GABAergic IPSCs in granule cells of the mouse dentate gyrus. A, Spontaneous GABAA receptor-mediated IPSCs recorded in WT and BDNF+/− mice. The action-potential-driven sIPSCs recorded without TTX showed a substantial increase by 65% in BDNF+/− slices. B, Brain slices from WT mice were incubated with either a control antibody (human Fc, 0.74 μg/ml) for 4 h or TrkB-Fc (2.2 μg/ml). In TrkB-Fc, the sIPSC frequency was 200% larger than with human FC. C, Recordings of sIPSCs in control, and in a slice where K-252a (200 nm) was used to inhibit TrkB. The latter slices were incubated with K-252a for 1 h, while control slices were incubated for 1 h with vehicle. K-252a increased the sIPSC frequency by 95%. D, Histogram summarizing the frequency of sIPSCs.

    Article Snippet: All drugs and chemicals were from Sigma-Aldrich except for TTX and cleavage-resistant proBDNF (Alomone), and recombinant human TrkB-Fc chimera (#688-TK) and recombinant human IgG1-Fc (#110-HG) (R&D Systems).

    Techniques: Incubation