trkb fc (Alomone Labs)


Structured Review
Trkb Fc, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/trkb fc/product/Alomone Labs
Average 91 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
trkb fc (Alomone Labs)


Structured Review
Trkb Fc, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/trkb fc/product/Alomone Labs
Average 91 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
recombinant human trkb fc chimera (Alomone Labs)


Structured Review

Recombinant Human Trkb Fc Chimera, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/recombinant human trkb fc chimera/product/Alomone Labs
Average 91 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
1) Product Images from "Mature BDNF, But Not proBDNF, Reduces Excitability of Fast-Spiking Interneurons in Mouse Dentate Gyrus"
Article Title: Mature BDNF, But Not proBDNF, Reduces Excitability of Fast-Spiking Interneurons in Mouse Dentate Gyrus
Journal: The Journal of Neuroscience
doi: 10.1523/JNEUROSCI.2978-09.2009

Figure Legend Snippet: Chronic or acute reductions in BDNF lead to increased frequency of spontaneous IPSCs in granule cells involving TrkB receptors. Whole-cell recordings of GABAergic IPSCs in granule cells of the mouse dentate gyrus. A, Spontaneous GABAA receptor-mediated IPSCs recorded in WT and BDNF+/− mice. The action-potential-driven sIPSCs recorded without TTX showed a substantial increase by 65% in BDNF+/− slices. B, Brain slices from WT mice were incubated with either a control antibody (human Fc, 0.74 μg/ml) for 4 h or TrkB-Fc (2.2 μg/ml). In TrkB-Fc, the sIPSC frequency was 200% larger than with human FC. C, Recordings of sIPSCs in control, and in a slice where K-252a (200 nm) was used to inhibit TrkB. The latter slices were incubated with K-252a for 1 h, while control slices were incubated for 1 h with vehicle. K-252a increased the sIPSC frequency by 95%. D, Histogram summarizing the frequency of sIPSCs.
Techniques Used: Incubation
recombinant human trkb fc chimera (Alomone Labs)


Structured Review
Recombinant Human Trkb Fc Chimera, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/recombinant human trkb fc chimera/product/Alomone Labs
Average 91 stars, based on 1 article reviews
Price from $9.99 to $1999.99