pf 04856264 by alomone  (Alomone Labs)


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    Alomone Labs pf 04856264 by alomone
    Effect on isoPLB on I Na in GH 3 cells. We bathed cells in a Ca 2+ -free Tyrode’s solution containing 0.5 mM CdCl 2 and 10 mM TEA, and the pipette was filled up with a Cs + -containing solution. ( A ) Original current traces obtained in the absence (a) and presence of 10 μM isoPLB (b) or 10 μM isoPLB plus 3 μM <t>PF-04856264.</t> The top part depicts the voltage protocol applied to the tested cell. ( B ) Summary bar graph showing the effect of isoPLB, PLB, isoPLB plus PF-04856264, and isoPLB plus TTX on the peak amplitude of I Na during brief depolarizing pulse (30 ms in duration) from −100 to −10 mV (mean ± SEM; n = 7 for each bar). * Significantly different from control ( p < 0.05) and ** significantly different from control ( p < 0.01). The analysis among different groups was performed with ANOVA-1 ( p < 0.05).
    Pf 04856264 By Alomone, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pf 04856264 by alomone/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    pf 04856264 by alomone - by Bioz Stars, 2023-09
    93/100 stars

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    1) Product Images from "The Effectiveness of Isoplumbagin and Plumbagin in Regulating Amplitude, Gating Kinetics, and Voltage-Dependent Hysteresis of erg -mediated K + Currents"

    Article Title: The Effectiveness of Isoplumbagin and Plumbagin in Regulating Amplitude, Gating Kinetics, and Voltage-Dependent Hysteresis of erg -mediated K + Currents

    Journal: Biomedicines

    doi: 10.3390/biomedicines10040780

    Effect on isoPLB on I Na in GH 3 cells. We bathed cells in a Ca 2+ -free Tyrode’s solution containing 0.5 mM CdCl 2 and 10 mM TEA, and the pipette was filled up with a Cs + -containing solution. ( A ) Original current traces obtained in the absence (a) and presence of 10 μM isoPLB (b) or 10 μM isoPLB plus 3 μM PF-04856264. The top part depicts the voltage protocol applied to the tested cell. ( B ) Summary bar graph showing the effect of isoPLB, PLB, isoPLB plus PF-04856264, and isoPLB plus TTX on the peak amplitude of I Na during brief depolarizing pulse (30 ms in duration) from −100 to −10 mV (mean ± SEM; n = 7 for each bar). * Significantly different from control ( p < 0.05) and ** significantly different from control ( p < 0.01). The analysis among different groups was performed with ANOVA-1 ( p < 0.05).
    Figure Legend Snippet: Effect on isoPLB on I Na in GH 3 cells. We bathed cells in a Ca 2+ -free Tyrode’s solution containing 0.5 mM CdCl 2 and 10 mM TEA, and the pipette was filled up with a Cs + -containing solution. ( A ) Original current traces obtained in the absence (a) and presence of 10 μM isoPLB (b) or 10 μM isoPLB plus 3 μM PF-04856264. The top part depicts the voltage protocol applied to the tested cell. ( B ) Summary bar graph showing the effect of isoPLB, PLB, isoPLB plus PF-04856264, and isoPLB plus TTX on the peak amplitude of I Na during brief depolarizing pulse (30 ms in duration) from −100 to −10 mV (mean ± SEM; n = 7 for each bar). * Significantly different from control ( p < 0.05) and ** significantly different from control ( p < 0.01). The analysis among different groups was performed with ANOVA-1 ( p < 0.05).

    Techniques Used: Transferring

    rabbit affinity purified polyclonal antibody against amino acids 251 265  (Alomone Labs)


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    Alomone Labs rabbit affinity purified polyclonal antibody against amino acids 251 265
    Rabbit Affinity Purified Polyclonal Antibody Against Amino Acids 251 265, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit affinity purified polyclonal antibody against amino acids 251 265/product/Alomone Labs
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    rabbit affinity purified polyclonal antibody against amino acids 251 265 - by Bioz Stars, 2023-09
    86/100 stars

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    pf 04856264 by alomone  (Alomone Labs)


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    Alomone Labs pf 04856264 by alomone
    Effect on isoPLB on I Na in GH 3 cells. We bathed cells in a Ca 2+ -free Tyrode’s solution containing 0.5 mM CdCl 2 and 10 mM TEA, and the pipette was filled up with a Cs + -containing solution. ( A ) Original current traces obtained in the absence (a) and presence of 10 μM isoPLB (b) or 10 μM isoPLB plus 3 μM <t>PF-04856264.</t> The top part depicts the voltage protocol applied to the tested cell. ( B ) Summary bar graph showing the effect of isoPLB, PLB, isoPLB plus PF-04856264, and isoPLB plus TTX on the peak amplitude of I Na during brief depolarizing pulse (30 ms in duration) from −100 to −10 mV (mean ± SEM; n = 7 for each bar). * Significantly different from control ( p < 0.05) and ** significantly different from control ( p < 0.01). The analysis among different groups was performed with ANOVA-1 ( p < 0.05).
    Pf 04856264 By Alomone, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pf 04856264 by alomone/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    pf 04856264 by alomone - by Bioz Stars, 2023-09
    93/100 stars

    Images

    1) Product Images from "The Effectiveness of Isoplumbagin and Plumbagin in Regulating Amplitude, Gating Kinetics, and Voltage-Dependent Hysteresis of erg -mediated K + Currents"

    Article Title: The Effectiveness of Isoplumbagin and Plumbagin in Regulating Amplitude, Gating Kinetics, and Voltage-Dependent Hysteresis of erg -mediated K + Currents

    Journal: Biomedicines

    doi: 10.3390/biomedicines10040780

    Effect on isoPLB on I Na in GH 3 cells. We bathed cells in a Ca 2+ -free Tyrode’s solution containing 0.5 mM CdCl 2 and 10 mM TEA, and the pipette was filled up with a Cs + -containing solution. ( A ) Original current traces obtained in the absence (a) and presence of 10 μM isoPLB (b) or 10 μM isoPLB plus 3 μM PF-04856264. The top part depicts the voltage protocol applied to the tested cell. ( B ) Summary bar graph showing the effect of isoPLB, PLB, isoPLB plus PF-04856264, and isoPLB plus TTX on the peak amplitude of I Na during brief depolarizing pulse (30 ms in duration) from −100 to −10 mV (mean ± SEM; n = 7 for each bar). * Significantly different from control ( p < 0.05) and ** significantly different from control ( p < 0.01). The analysis among different groups was performed with ANOVA-1 ( p < 0.05).
    Figure Legend Snippet: Effect on isoPLB on I Na in GH 3 cells. We bathed cells in a Ca 2+ -free Tyrode’s solution containing 0.5 mM CdCl 2 and 10 mM TEA, and the pipette was filled up with a Cs + -containing solution. ( A ) Original current traces obtained in the absence (a) and presence of 10 μM isoPLB (b) or 10 μM isoPLB plus 3 μM PF-04856264. The top part depicts the voltage protocol applied to the tested cell. ( B ) Summary bar graph showing the effect of isoPLB, PLB, isoPLB plus PF-04856264, and isoPLB plus TTX on the peak amplitude of I Na during brief depolarizing pulse (30 ms in duration) from −100 to −10 mV (mean ± SEM; n = 7 for each bar). * Significantly different from control ( p < 0.05) and ** significantly different from control ( p < 0.01). The analysis among different groups was performed with ANOVA-1 ( p < 0.05).

    Techniques Used: Transferring

    rat syntaxin 1  (Alomone Labs)


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    Alomone Labs rat syntaxin 1
    Rat Syntaxin 1, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 86 stars, based on 1 article reviews
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    rat syntaxin 1 - by Bioz Stars, 2023-09
    86/100 stars

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    rat syntaxin1a  (Alomone Labs)


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    Alomone Labs rat syntaxin1a
    Rat Syntaxin1a, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rat syntaxin1a/product/Alomone Labs
    Average 86 stars, based on 1 article reviews
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    rat syntaxin1a - by Bioz Stars, 2023-09
    86/100 stars

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    figs 1 3  (Alomone Labs)


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    Alomone Labs figs 1 3
    Figs 1 3, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/figs 1 3/product/Alomone Labs
    Average 86 stars, based on 1 article reviews
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    figs 1 3 - by Bioz Stars, 2023-09
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