Tityustoxin, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 85/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
Average 85 stars, based on 2 article reviews
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1) Product Images from "Use-Dependent Activation of Neuronal Kv1.2 Channel Complexes"
Article Title: Use-Dependent Activation of Neuronal Kv1.2 Channel Complexes
Journal: The Journal of Neuroscience
Figure Legend Snippet: Variability of gating properties of tityustoxin-sensitive channels in dissociated hippocampal neurons. A , Summary of use-dependent properties of neurons subjected to repetitive depolarizations at the indicated frequencies. Cells exhibit a range of use-dependent activation and/or inactivation. B , Sample traces of 10 Hz recordings of tityustoxin-sensitive currents from hippocampal neurons, illustrating extreme cases of either use-dependent activation (top) or inactivation (bottom). C , Sample traces from longer pulse durations, illustrating the cell-to-cell variability of inactivation, and the emergence of use-dependent potentiation in the sustained current component of some cells with pronounced inactivation (middle and right).
Techniques Used: Activation Assay