Arcaine Sulfate, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
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1) Product Images from "Two de novo GluN2B mutations affect multiple NMDAR-functions and instigate severe pediatric encephalopathy"
Article Title: Two de novo GluN2B mutations affect multiple NMDAR-functions and instigate severe pediatric encephalopathy
Figure Legend Snippet: LBD mutations do not affect spermine binding site. ( a ) Representative traces from oocytes co-expressing hGluN1a and hGluN2B- wt (blue) or GluN2B-G689C (cyan) or G689S (red) in response to block by arcaine (200 μM), after receptors have been activated by saturating glycine (100 μM) and glutamate (5 mM) at pH 6.5. Then, application of incrementing concentrations of spermine (concentration indicated next to plot; in μM) are added in the presence of arcaine, showing increases of the current despite antagonist. Arrowhead indicates I basal at pH 6.5, prior block by arcaine. ( b ) Summary of arcaine-dependent antagonism of the current. ( c ) Summary of spermine potentiation at pH=6.5 in the presence of 200 μM arcaine. ( d ) Summary of I basal at pH=6.5, showing that 2B wt receptors exhibit smallest I basal . *, p
Techniques Used: Binding Assay, Expressing, Blocking Assay, Concentration Assay