bicuculline (Alomone Labs)
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Alomone Labs manufactures this product 
93
Structured Review
Alomone Labs
bicuculline
Bicuculline, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bicuculline/product/Alomone Labs
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Bicuculline, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bicuculline/product/Alomone Labs
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
bicuculline - by Bioz Stars,
2023-02
93/100 stars
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nacl (Alomone Labs)
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Alomone Labs manufactures this product
86
Structured Review
Alomone Labs
nacl
Nacl, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nacl/product/Alomone Labs
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Nacl, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nacl/product/Alomone Labs
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
nacl - by Bioz Stars,
2023-02
86/100 stars
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bicuculline (Alomone Labs)
Alomone Labs is a verified supplier
Alomone Labs manufactures this product
93
Structured Review
Alomone Labs
bicuculline
Bicuculline, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bicuculline/product/Alomone Labs
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Bicuculline, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bicuculline/product/Alomone Labs
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
bicuculline - by Bioz Stars,
2023-02
93/100 stars
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bicuculline (Alomone Labs)
Alomone Labs is a verified supplier
Alomone Labs manufactures this product
93
Structured Review
Alomone Labs
bicuculline
Bicuculline, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bicuculline/product/Alomone Labs
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Bicuculline, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bicuculline/product/Alomone Labs
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
bicuculline - by Bioz Stars,
2023-02
93/100 stars
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bicuculline (Alomone Labs)
Alomone Labs is a verified supplier
Alomone Labs manufactures this product
93
Structured Review
Alomone Labs
bicuculline
Bicuculline, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bicuculline/product/Alomone Labs
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Bicuculline, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bicuculline/product/Alomone Labs
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
bicuculline - by Bioz Stars,
2023-02
93/100 stars
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bicuculline (Alomone Labs)
Alomone Labs is a verified supplier
Alomone Labs manufactures this product
93
Structured Review
Alomone Labs
bicuculline
Bicuculline, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bicuculline/product/Alomone Labs
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Bicuculline, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bicuculline/product/Alomone Labs
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
bicuculline - by Bioz Stars,
2023-02
93/100 stars
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bicuculline (Alomone Labs)
Alomone Labs is a verified supplier
Alomone Labs manufactures this product
93
Structured Review
Alomone Labs
bicuculline
Bicuculline, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bicuculline/product/Alomone Labs
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Bicuculline, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bicuculline/product/Alomone Labs
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
bicuculline - by Bioz Stars,
2023-02
93/100 stars
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zinc58368839 (Alomone Labs)
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Alomone Labs manufactures this product
91
Structured Review
Alomone Labs
zinc58368839
![Use of intersubunit allosteric pocket “signature mutants” to investigate the site of action for brilliant blue G, KN-62, calmidazolium, <t>ZINC58368839,</t> and PPADS. (A) Concentration-dependent inhibition by P2X7 antagonists of response to an EC 90 concentration of ATP for P2X7-2N β (black), F88A (firebrick), T90V (orange), D92A (yellow), F103A (green), and V312A (purple). (B) Top panel: P2X7R overview with “signature mutants” residues shown as spheres; colors as in (A). Other panels: View from the top of the extracellular domains along the central axis perpendicular to the membrane. The P2X7R model is shown as cartoon with the three subunits highlighted in light blue, light pink, and gray with the docked pose of the antagonist shown as spheres. (C) Top panel: Surface representation of entrance to allosteric pocket. Other panels: Zoom into the proposed binding site, one subunit [light blue in (B)] is omitted for clarity. Residues F88, T90, D92, F103, and V312 and the respective antagonist are shown as sticks [colors as in (A) and (B)].](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_1605/pmc06701605/pmc06701605__mol.119.116715f5.jpg)
Zinc58368839, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/zinc58368839/product/Alomone Labs
Average 91 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Zinc58368839, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/zinc58368839/product/Alomone Labs
Average 91 stars, based on 1 article reviews
Price from $9.99 to $1999.99
zinc58368839 - by Bioz Stars,
2023-02
91/100 stars
Images
1) Product Images from "Mapping the Site of Action of Human P2X7 Receptor Antagonists AZ11645373, Brilliant Blue G, KN-62, Calmidazolium, and ZINC58368839 to the Intersubunit Allosteric Pocket "
Article Title: Mapping the Site of Action of Human P2X7 Receptor Antagonists AZ11645373, Brilliant Blue G, KN-62, Calmidazolium, and ZINC58368839 to the Intersubunit Allosteric Pocket
Journal: Molecular Pharmacology
doi: 10.1124/mol.119.116715
Figure Legend Snippet: Use of intersubunit allosteric pocket “signature mutants” to investigate the site of action for brilliant blue G, KN-62, calmidazolium, ZINC58368839, and PPADS. (A) Concentration-dependent inhibition by P2X7 antagonists of response to an EC 90 concentration of ATP for P2X7-2N β (black), F88A (firebrick), T90V (orange), D92A (yellow), F103A (green), and V312A (purple). (B) Top panel: P2X7R overview with “signature mutants” residues shown as spheres; colors as in (A). Other panels: View from the top of the extracellular domains along the central axis perpendicular to the membrane. The P2X7R model is shown as cartoon with the three subunits highlighted in light blue, light pink, and gray with the docked pose of the antagonist shown as spheres. (C) Top panel: Surface representation of entrance to allosteric pocket. Other panels: Zoom into the proposed binding site, one subunit [light blue in (B)] is omitted for clarity. Residues F88, T90, D92, F103, and V312 and the respective antagonist are shown as sticks [colors as in (A) and (B)].
Techniques Used: Concentration Assay, Inhibition, Binding Assay
bicuculline (Alomone Labs)
Alomone Labs is a verified supplier
Alomone Labs manufactures this product
93
Structured Review
Alomone Labs
bicuculline
Bicuculline, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bicuculline/product/Alomone Labs
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Bicuculline, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bicuculline/product/Alomone Labs
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
bicuculline - by Bioz Stars,
2023-02
93/100 stars
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bicuculline (Alomone Labs)
Alomone Labs is a verified supplier
Alomone Labs manufactures this product
93
Structured Review
Alomone Labs
bicuculline
Bicuculline, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bicuculline/product/Alomone Labs
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Bicuculline, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bicuculline/product/Alomone Labs
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
bicuculline - by Bioz Stars,
2023-02
93/100 stars