rabbit anti pdcd4 (Boster Bio)


Structured Review

Rabbit Anti Pdcd4, supplied by Boster Bio, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rabbit anti pdcd4/product/Boster Bio
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
1) Product Images from "Andrographolide Suppresses the Growth and Metastasis of Luminal-Like Breast Cancer by Inhibiting the NF-κB/miR-21-5p/PDCD4 Signaling Pathway"
Article Title: Andrographolide Suppresses the Growth and Metastasis of Luminal-Like Breast Cancer by Inhibiting the NF-κB/miR-21-5p/PDCD4 Signaling Pathway
Journal: Frontiers in Cell and Developmental Biology
doi: 10.3389/fcell.2021.643525

Figure Legend Snippet: Andrographolide (Andro) inhibits breast cancer cell proliferation, migration, and invasion via NF-κB/miR-21-5p/PDCD4 signaling. (A) Heat map of the qRT-PCR data of miRNA expression in MCF-7 cells with or without NF-κB inhibition. APDC: NF-κB inhibitor. (B) miR-21-5p expression in breast cancer tissue and MCF cells was also detected using qRT-PCR. miR-21-5p was markedly suppressed by Andro in MCF-7 cells and MMTV-PyMT mice. (C) Colony formation, wound healing, Transwell migration, and Matrigel invasion assay. Immunohistochemistry (D) and Immunoblotting assay (E) for PDCD4 expression in DMSO- and Andro-treated MMTV-PyMT mice. (F) Immunoblotting analysis for PDCD4 expression in MCF-7 cells. (G) Schematic of the mechanisms of Andro-mediated effect on luminal-like breast cancer growth and metastasis. Quantitative data are expressed as the mean ± SD, n = 3. Significant effect: * P
Techniques Used: Migration, Quantitative RT-PCR, Expressing, Inhibition, Mouse Assay, Invasion Assay, Immunohistochemistry