giiib  (Alomone Labs)


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  • 93
    Name:
    mu Conotoxin GIIIB
    Description:
    A Selective Blocker of Skeletal Muscle NaV1 4 Channels
    Catalog Number:
    C-270
    Price:
    161.0
    Category:
    Toxin
    Source:
    Synthetic peptide
    Applications:
    0
    Purity:
    >99% (HPLC)
    Size:
    50 mcg
    Format:
    Lyophilized powder.
    Formula:
    C101H175N39O30S7
    Molecular Weight:
    2640 Da.
    Molecule Name:
    mu-Conotoxin GIIIB, Myotoxin II, Geographutoxin II, GTx-II
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    Structured Review

    Alomone Labs giiib
    mu Conotoxin GIIIB
    A Selective Blocker of Skeletal Muscle NaV1 4 Channels
    https://www.bioz.com/result/giiib/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    giiib - by Bioz Stars, 2021-09
    93/100 stars

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    Related Articles

    other:

    Article Title: Direct optical activation of skeletal muscle fibres efficiently controls muscle contraction and attenuates denervation atrophy
    Article Snippet: Drug treatments Muscle contractions were determined in the presence of the following drugs: 10 μM d-tubocurarine (Sigma T2379), 500 nM TTX (Abcam ab120055), 1 μM μ-conotoxin GIIIB (Alomone Labs C-270), 50 μM 4-methyl-N -(phenylmethyl) benzene sulfonamide (BTS) (Tocris Bioscience no 1870) and 10 μM blebbistatin (Sigma B0560).

    Article Title: Age-Dependent Contribution of P/Q- and R-Type Ca2+ Channels to Neuromuscular Transmission in Lethargic Mice
    Article Snippet: HEPES, EGTA, paraformaldehyde, Triton X-100, and tetramethylrhodamine α -bungarotoxin were all purchased from Sigma-Aldrich. μ -Conotoxin GIIIB and antibodies against the various α 1 -subunits were obtained from Alomone Labs.

    Concentration Assay:

    Article Title: Muscle Nicotinic Acetylcholine Receptors May Mediate Trans-Synaptic Signaling at the Mouse Neuromuscular Junction
    Article Snippet: .. In these experiments, muscle fibers were not crushed and contraction was prevented by addition of μ-conotoxin GIIIB (μ-Ctx; Alomone Labs) to the external solution (final toxin concentration was 1–3 μ m ) to inhibit muscle Na+ channels. ..

    Article Title: Aging Blunts Sympathetic Neuron Regulation of Motoneurons Synaptic Vesicle Release Mediated by β1- and α2B-Adrenergic Receptors in Geriatric Mice
    Article Snippet: .. The SPNL preparation was incubated for 30 minutes in μ-conotoxin GIIIB (a.k.a. myotoxin II, geographutoxin II, GTx-II; cat. C270; Alomone Labs, Jerusalem, Israel), a selective blocker of skeletal muscle Nav1.4 channels, used at a concentration of 1 µM to prevent muscle contraction (see below). ..

    Article Title: Muscle Nicotinic Acetylcholine Receptors May Mediate Trans-Synaptic Signaling at the Mouse Neuromuscular Junction
    Article Snippet: .. In these experiments, muscle fibers were not crushed and contraction was prevented by addition of μ-conotoxin GIIIB (μ-Ctx; Alomone Labs) to the external solution (final toxin concentration was 1–3 μ m ) to inhibit muscle Na+ channels. ..

    Incubation:

    Article Title: Aging Blunts Sympathetic Neuron Regulation of Motoneurons Synaptic Vesicle Release Mediated by β1- and α2B-Adrenergic Receptors in Geriatric Mice
    Article Snippet: .. The SPNL preparation was incubated for 30 minutes in μ-conotoxin GIIIB (a.k.a. myotoxin II, geographutoxin II, GTx-II; cat. C270; Alomone Labs, Jerusalem, Israel), a selective blocker of skeletal muscle Nav1.4 channels, used at a concentration of 1 µM to prevent muscle contraction (see below). ..

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