bavachin  (MedChemExpress)


Bioz Verified Symbol MedChemExpress is a verified supplier
Bioz Manufacturer Symbol MedChemExpress manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 93

    Structured Review

    MedChemExpress bavachin
    P53 inactivation upregulates SLC7A11 to alleviate <t>bavachin-induced</t> ferroptosis in osteosarcoma (OS) cells. OS cells were pretreated <t>with</t> <t>pifithrin-</t> α (PFT- α , 5 μ M) followed by treatment with bavachin (40 μ M, 24 h). (a, b) Western blotting shows the relative levels of P53, SLC7A11, and GPX4 protein expression. (c) PFT- α (5 μ M) restores bavachin-induced GSH depletion. (d, e) PFT- α reduces bavachin-induced ROS and MDA accumulation. (f) PFT- α recovers bavachin-induced ferroptosis in OS cells. ∗ p < 0.05, ∗∗ p < 0.01, and ∗∗∗ p < 0.001.
    Bavachin, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bavachin/product/MedChemExpress
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    bavachin - by Bioz Stars, 2023-06
    93/100 stars

    Images

    1) Product Images from "Bavachin Induces Ferroptosis through the STAT3/P53/SLC7A11 Axis in Osteosarcoma Cells"

    Article Title: Bavachin Induces Ferroptosis through the STAT3/P53/SLC7A11 Axis in Osteosarcoma Cells

    Journal: Oxidative Medicine and Cellular Longevity

    doi: 10.1155/2021/1783485

    P53 inactivation upregulates SLC7A11 to alleviate bavachin-induced ferroptosis in osteosarcoma (OS) cells. OS cells were pretreated with pifithrin- α (PFT- α , 5 μ M) followed by treatment with bavachin (40 μ M, 24 h). (a, b) Western blotting shows the relative levels of P53, SLC7A11, and GPX4 protein expression. (c) PFT- α (5 μ M) restores bavachin-induced GSH depletion. (d, e) PFT- α reduces bavachin-induced ROS and MDA accumulation. (f) PFT- α recovers bavachin-induced ferroptosis in OS cells. ∗ p < 0.05, ∗∗ p < 0.01, and ∗∗∗ p < 0.001.
    Figure Legend Snippet: P53 inactivation upregulates SLC7A11 to alleviate bavachin-induced ferroptosis in osteosarcoma (OS) cells. OS cells were pretreated with pifithrin- α (PFT- α , 5 μ M) followed by treatment with bavachin (40 μ M, 24 h). (a, b) Western blotting shows the relative levels of P53, SLC7A11, and GPX4 protein expression. (c) PFT- α (5 μ M) restores bavachin-induced GSH depletion. (d, e) PFT- α reduces bavachin-induced ROS and MDA accumulation. (f) PFT- α recovers bavachin-induced ferroptosis in OS cells. ∗ p < 0.05, ∗∗ p < 0.01, and ∗∗∗ p < 0.001.

    Techniques Used: Western Blot, Expressing

    Similar Products

  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 93
    MedChemExpress bavachin
    P53 inactivation upregulates SLC7A11 to alleviate <t>bavachin-induced</t> ferroptosis in osteosarcoma (OS) cells. OS cells were pretreated <t>with</t> <t>pifithrin-</t> α (PFT- α , 5 μ M) followed by treatment with bavachin (40 μ M, 24 h). (a, b) Western blotting shows the relative levels of P53, SLC7A11, and GPX4 protein expression. (c) PFT- α (5 μ M) restores bavachin-induced GSH depletion. (d, e) PFT- α reduces bavachin-induced ROS and MDA accumulation. (f) PFT- α recovers bavachin-induced ferroptosis in OS cells. ∗ p < 0.05, ∗∗ p < 0.01, and ∗∗∗ p < 0.001.
    Bavachin, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bavachin/product/MedChemExpress
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    bavachin - by Bioz Stars, 2023-06
    93/100 stars
      Buy from Supplier

    Image Search Results


    P53 inactivation upregulates SLC7A11 to alleviate bavachin-induced ferroptosis in osteosarcoma (OS) cells. OS cells were pretreated with pifithrin- α (PFT- α , 5 μ M) followed by treatment with bavachin (40 μ M, 24 h). (a, b) Western blotting shows the relative levels of P53, SLC7A11, and GPX4 protein expression. (c) PFT- α (5 μ M) restores bavachin-induced GSH depletion. (d, e) PFT- α reduces bavachin-induced ROS and MDA accumulation. (f) PFT- α recovers bavachin-induced ferroptosis in OS cells. ∗ p < 0.05, ∗∗ p < 0.01, and ∗∗∗ p < 0.001.

    Journal: Oxidative Medicine and Cellular Longevity

    Article Title: Bavachin Induces Ferroptosis through the STAT3/P53/SLC7A11 Axis in Osteosarcoma Cells

    doi: 10.1155/2021/1783485

    Figure Lengend Snippet: P53 inactivation upregulates SLC7A11 to alleviate bavachin-induced ferroptosis in osteosarcoma (OS) cells. OS cells were pretreated with pifithrin- α (PFT- α , 5 μ M) followed by treatment with bavachin (40 μ M, 24 h). (a, b) Western blotting shows the relative levels of P53, SLC7A11, and GPX4 protein expression. (c) PFT- α (5 μ M) restores bavachin-induced GSH depletion. (d, e) PFT- α reduces bavachin-induced ROS and MDA accumulation. (f) PFT- α recovers bavachin-induced ferroptosis in OS cells. ∗ p < 0.05, ∗∗ p < 0.01, and ∗∗∗ p < 0.001.

    Article Snippet: Bavachin was purchased from MCE (China), and pifithrin- α (PFT- α ), deferoxamine (DFO), ferrostatin-1 (Fer-1), and liproxstatin-1 (Lip-1) were purchased from Topscience (China).

    Techniques: Western Blot, Expressing