4e2rcat (MedChemExpress)


Structured Review

4e2rcat, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/4e2rcat/product/MedChemExpress
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
1) Product Images from "Single-Molecule Dynamics of SARS-CoV-2 5’ Cap Recognition by Human eIF4F"
Article Title: Single-Molecule Dynamics of SARS-CoV-2 5’ Cap Recognition by Human eIF4F
Journal: bioRxiv
doi: 10.1101/2021.05.26.445185

Figure Legend Snippet: SARS-CoV-2 untranslated regions support eIF4F-dependent translation. (A) Schematic of luciferase reporter construct. (B) Inhibition of reporter translation in a HeLa cell-free translation assay by the small-molecule inhibitor of eIF4E–eIF4G interaction, 4E2RCat. Luciferase translation is normalized to a control reaction without inhibitor. (C) Inhibition of reporter translation by the small-molecule eIF4A inhibitor, RocA (rocaglamide). Error bars in (B) and (C) reflect the standard deviation from three independent luciferase reactions, with the luminescence from each independent reaction measured in triplicate.
Techniques Used: Luciferase, Construct, Inhibition, Standard Deviation