mouse anti mouse c5 (Hycult Biotech)


Structured Review

Mouse Anti Mouse C5, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mouse anti mouse c5/product/Hycult Biotech
Average 91 stars, based on 1 article reviews
Images
1) Product Images from "Dysregulation of the complement cascade in the hSOD1 G93A transgenic mouse model of amyotrophic lateral sclerosis"
Article Title: Dysregulation of the complement cascade in the hSOD1 G93A transgenic mouse model of amyotrophic lateral sclerosis
Journal: Journal of Neuroinflammation
doi: 10.1186/1742-2094-10-119

Figure Legend Snippet: Summary of antibodies used for immunohistochemistry
Techniques Used:

Figure Legend Snippet: Expression and localisation of C5 and C5a in hSOD1 G93A and wild-type mice during disease progression. (A) mRNA expression profile of C5 in lumbar spinal cord of hSOD1 G93A mice relative to wild-type (WT) mice. Dashed line, baseline expression in WT controls at each time point. (B) Protein expression of C5a in the lumbar spinal cord of hSOD1 G93A mice has decreased by end stage (ES) when compared with WT mice. (A , B) Data expressed as mean ± standard error of the mean ( n = 6 mice/group; * P <0.05, Student t test). (C) to (H) Double immunolabelling for C5 (red) with cellular makers (green) for motor neurons (ChAT; C and D , arrows), astrocytes (g lial fibrillary acidic protein (GFAP), E and F ), and microglia (CD11b; G and H ), in the ventral lumbar spinal cord region of hSOD1 G93A mice (D , F and H) and WT mice (C , E and G) at end stage. Co-localisation of C5 with these cellular markers is seen as a merge of green and red ( for example, white arrows in C , D , and H) . PS, pre-symptomatic; OS, onset; MS, mid-symptomatic; ES, end-stage. Scale bar for C to H = 20 μm.
Techniques Used: Expressing