plasma lipopolysaccharide binding protein  (Hycult Biotech)


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    Hycult Biotech plasma lipopolysaccharide binding protein
    Plasma Lipopolysaccharide Binding Protein, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    plasma lipopolysaccharide binding protein  (Hycult Biotech)


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    Hycult Biotech plasma lipopolysaccharide binding protein
    Plasma Lipopolysaccharide Binding Protein, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    plasma lipopolysaccharide binding protein  (Hycult Biotech)


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    Hycult Biotech plasma lipopolysaccharide binding protein
    Plasma Lipopolysaccharide Binding Protein, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    human bpi elisa kit  (Hycult Biotech)


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    Hycult Biotech human bpi elisa kit
    Human Bpi Elisa Kit, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    human bpi concentrations  (Hycult Biotech)


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    Hycult Biotech human bpi concentrations
    Validation of OLFM4 expression at the transcriptional and protein level. ( A ) Expression of ten critical genes was compared between healthy controls, septic patients, and sepsis-related ARDS patients by quantitative real-time PCR. Differences between two groups were analyzed. * p < 0.05, ** p < 0.01 versus CT group, # p < 0.05 versus sepsis group. ( B , C and D ) Plasma OLFM4, LCN2 and <t>BPI</t> expressions were compared between healthy controls, septic patients, and sepsis-related ARDS patients <t>using</t> <t>ELISA</t> kit. ** p < 0.01 versus control group, *** p < 0.001 versus control group, # p < 0.05 versus sepsis group. ( E ) Analyses of ROC curves of plasma OLFM4, LCN2 and BPI expression. ROC curves were generated and the area under the ROC was used to compare plasma OLFM4, LCN2 and BPI expressions in the sepsis group and sepsis-related ARDS group.
    Human Bpi Concentrations, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    1) Product Images from "OLFM4 Regulates Lung Epithelial Cell Function in Sepsis-Associated ARDS/ALI via LDHA-Mediated NF-κB Signaling"

    Article Title: OLFM4 Regulates Lung Epithelial Cell Function in Sepsis-Associated ARDS/ALI via LDHA-Mediated NF-κB Signaling

    Journal: Journal of Inflammation Research

    doi: 10.2147/JIR.S335915

    Validation of OLFM4 expression at the transcriptional and protein level. ( A ) Expression of ten critical genes was compared between healthy controls, septic patients, and sepsis-related ARDS patients by quantitative real-time PCR. Differences between two groups were analyzed. * p < 0.05, ** p < 0.01 versus CT group, # p < 0.05 versus sepsis group. ( B , C and D ) Plasma OLFM4, LCN2 and BPI expressions were compared between healthy controls, septic patients, and sepsis-related ARDS patients using ELISA kit. ** p < 0.01 versus control group, *** p < 0.001 versus control group, # p < 0.05 versus sepsis group. ( E ) Analyses of ROC curves of plasma OLFM4, LCN2 and BPI expression. ROC curves were generated and the area under the ROC was used to compare plasma OLFM4, LCN2 and BPI expressions in the sepsis group and sepsis-related ARDS group.
    Figure Legend Snippet: Validation of OLFM4 expression at the transcriptional and protein level. ( A ) Expression of ten critical genes was compared between healthy controls, septic patients, and sepsis-related ARDS patients by quantitative real-time PCR. Differences between two groups were analyzed. * p < 0.05, ** p < 0.01 versus CT group, # p < 0.05 versus sepsis group. ( B , C and D ) Plasma OLFM4, LCN2 and BPI expressions were compared between healthy controls, septic patients, and sepsis-related ARDS patients using ELISA kit. ** p < 0.01 versus control group, *** p < 0.001 versus control group, # p < 0.05 versus sepsis group. ( E ) Analyses of ROC curves of plasma OLFM4, LCN2 and BPI expression. ROC curves were generated and the area under the ROC was used to compare plasma OLFM4, LCN2 and BPI expressions in the sepsis group and sepsis-related ARDS group.

    Techniques Used: Expressing, Real-time Polymerase Chain Reaction, Enzyme-linked Immunosorbent Assay, Generated

    elisa kit  (Hycult Biotech)


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    Hycult Biotech elisa kit
    Validation of OLFM4 expression at the transcriptional and protein level. ( A ) Expression of ten critical genes was compared between healthy controls, septic patients, and sepsis-related ARDS patients by quantitative real-time PCR. Differences between two groups were analyzed. * p < 0.05, ** p < 0.01 versus CT group, # p < 0.05 versus sepsis group. ( B , C and D ) Plasma OLFM4, LCN2 <t>and</t> <t>BPI</t> expressions were compared between healthy controls, septic patients, and sepsis-related ARDS patients using <t>ELISA</t> kit. ** p < 0.01 versus control group, *** p < 0.001 versus control group, # p < 0.05 versus sepsis group. ( E ) Analyses of ROC curves of plasma OLFM4, LCN2 and BPI expression. ROC curves were generated and the area under the ROC was used to compare plasma OLFM4, LCN2 and BPI expressions in the sepsis group and sepsis-related ARDS group.
    Elisa Kit, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/elisa kit/product/Hycult Biotech
    Average 93 stars, based on 1 article reviews
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    elisa kit - by Bioz Stars, 2024-05
    93/100 stars

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    1) Product Images from "OLFM4 Regulates Lung Epithelial Cell Function in Sepsis-Associated ARDS/ALI via LDHA-Mediated NF-κB Signaling"

    Article Title: OLFM4 Regulates Lung Epithelial Cell Function in Sepsis-Associated ARDS/ALI via LDHA-Mediated NF-κB Signaling

    Journal: Journal of Inflammation Research

    doi: 10.2147/JIR.S335915

    Validation of OLFM4 expression at the transcriptional and protein level. ( A ) Expression of ten critical genes was compared between healthy controls, septic patients, and sepsis-related ARDS patients by quantitative real-time PCR. Differences between two groups were analyzed. * p < 0.05, ** p < 0.01 versus CT group, # p < 0.05 versus sepsis group. ( B , C and D ) Plasma OLFM4, LCN2 and BPI expressions were compared between healthy controls, septic patients, and sepsis-related ARDS patients using ELISA kit. ** p < 0.01 versus control group, *** p < 0.001 versus control group, # p < 0.05 versus sepsis group. ( E ) Analyses of ROC curves of plasma OLFM4, LCN2 and BPI expression. ROC curves were generated and the area under the ROC was used to compare plasma OLFM4, LCN2 and BPI expressions in the sepsis group and sepsis-related ARDS group.
    Figure Legend Snippet: Validation of OLFM4 expression at the transcriptional and protein level. ( A ) Expression of ten critical genes was compared between healthy controls, septic patients, and sepsis-related ARDS patients by quantitative real-time PCR. Differences between two groups were analyzed. * p < 0.05, ** p < 0.01 versus CT group, # p < 0.05 versus sepsis group. ( B , C and D ) Plasma OLFM4, LCN2 and BPI expressions were compared between healthy controls, septic patients, and sepsis-related ARDS patients using ELISA kit. ** p < 0.01 versus control group, *** p < 0.001 versus control group, # p < 0.05 versus sepsis group. ( E ) Analyses of ROC curves of plasma OLFM4, LCN2 and BPI expression. ROC curves were generated and the area under the ROC was used to compare plasma OLFM4, LCN2 and BPI expressions in the sepsis group and sepsis-related ARDS group.

    Techniques Used: Expressing, Real-time Polymerase Chain Reaction, Enzyme-linked Immunosorbent Assay, Generated

    bpi  (Hycult Biotech)


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    Hycult Biotech bpi
    LGM levels (mean ± SE) in individuals with healthy (n = 40) and unhealthy (n = 40) metabolic profiles in the pilot study.
    Bpi, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    bpi - by Bioz Stars, 2024-05
    93/100 stars

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    1) Product Images from "Identification of leaky gut-related markers as indicators of metabolic health in Dutch adults: The Nutrition Questionnaires plus (NQplus) study"

    Article Title: Identification of leaky gut-related markers as indicators of metabolic health in Dutch adults: The Nutrition Questionnaires plus (NQplus) study

    Journal: PLoS ONE

    doi: 10.1371/journal.pone.0252936

    LGM levels (mean ± SE) in individuals with healthy (n = 40) and unhealthy (n = 40) metabolic profiles in the pilot study.
    Figure Legend Snippet: LGM levels (mean ± SE) in individuals with healthy (n = 40) and unhealthy (n = 40) metabolic profiles in the pilot study.

    Techniques Used:

    hk314-02  (Hycult Biotech)


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    Hycult Biotech hk314-02
    Hk314 02, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/hk314-02/product/Hycult Biotech
    Average 93 stars, based on 1 article reviews
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    hk314-02 - by Bioz Stars, 2024-05
    93/100 stars

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    human bpi elisa kit  (Hycult Biotech)


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    Hycult Biotech human bpi elisa kit
    Elevated levels of <t>BPI</t> present in plasma and BAL of people with CF. (A , B) LPS levels in CF plasma and BAL correlated with CF-ABLE score. Quantification of an association between variables was achieved by Spearman correlation. (C , D) Comparative analysis of BPI present in plasma or BAL of Phe508del homozygous PWCF (CF), healthy controls (HC) or NCFB patients was performed by <t>ELISA.</t> (C) BPI levels were significantly increased in plasma of CF compared to HC (n=22 and n=14 subjects per group, respectively, p=0.007, Mann Whitney U-test). (D) BAL levels of BPI were significantly increased in CF (n=5) compared to HC (n=4) or NCFB patients (n=5) (p<0.0001, One-way ANOVA, followed by Bonferroni post-hoc test for selected groups). (E) BAL samples from HC, CF, NCFB or COPD were subjected to SDS-PAGE and Western blot analysis for BPI. An immuno-band of increased intensity for BPI was detected in CF BAL samples (top panels). Lower panel, a control immunoblot to ensure BPI specificity. The blot was halved, with one half probed with secondary antibody only with no BPI immune-bands visible (↑ indicates where blot was cut). Human BPI (hBPI) was used as a positive control. All measurements are means ± SEM from biological replicates.
    Human Bpi Elisa Kit, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human bpi elisa kit/product/Hycult Biotech
    Average 93 stars, based on 1 article reviews
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    human bpi elisa kit - by Bioz Stars, 2024-05
    93/100 stars

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    1) Product Images from "Targeting IgG Autoantibodies for Improved Cytotoxicity of Bactericidal Permeability Increasing Protein in Cystic Fibrosis"

    Article Title: Targeting IgG Autoantibodies for Improved Cytotoxicity of Bactericidal Permeability Increasing Protein in Cystic Fibrosis

    Journal: Frontiers in Pharmacology

    doi: 10.3389/fphar.2020.01098

    Elevated levels of BPI present in plasma and BAL of people with CF. (A , B) LPS levels in CF plasma and BAL correlated with CF-ABLE score. Quantification of an association between variables was achieved by Spearman correlation. (C , D) Comparative analysis of BPI present in plasma or BAL of Phe508del homozygous PWCF (CF), healthy controls (HC) or NCFB patients was performed by ELISA. (C) BPI levels were significantly increased in plasma of CF compared to HC (n=22 and n=14 subjects per group, respectively, p=0.007, Mann Whitney U-test). (D) BAL levels of BPI were significantly increased in CF (n=5) compared to HC (n=4) or NCFB patients (n=5) (p<0.0001, One-way ANOVA, followed by Bonferroni post-hoc test for selected groups). (E) BAL samples from HC, CF, NCFB or COPD were subjected to SDS-PAGE and Western blot analysis for BPI. An immuno-band of increased intensity for BPI was detected in CF BAL samples (top panels). Lower panel, a control immunoblot to ensure BPI specificity. The blot was halved, with one half probed with secondary antibody only with no BPI immune-bands visible (↑ indicates where blot was cut). Human BPI (hBPI) was used as a positive control. All measurements are means ± SEM from biological replicates.
    Figure Legend Snippet: Elevated levels of BPI present in plasma and BAL of people with CF. (A , B) LPS levels in CF plasma and BAL correlated with CF-ABLE score. Quantification of an association between variables was achieved by Spearman correlation. (C , D) Comparative analysis of BPI present in plasma or BAL of Phe508del homozygous PWCF (CF), healthy controls (HC) or NCFB patients was performed by ELISA. (C) BPI levels were significantly increased in plasma of CF compared to HC (n=22 and n=14 subjects per group, respectively, p=0.007, Mann Whitney U-test). (D) BAL levels of BPI were significantly increased in CF (n=5) compared to HC (n=4) or NCFB patients (n=5) (p<0.0001, One-way ANOVA, followed by Bonferroni post-hoc test for selected groups). (E) BAL samples from HC, CF, NCFB or COPD were subjected to SDS-PAGE and Western blot analysis for BPI. An immuno-band of increased intensity for BPI was detected in CF BAL samples (top panels). Lower panel, a control immunoblot to ensure BPI specificity. The blot was halved, with one half probed with secondary antibody only with no BPI immune-bands visible (↑ indicates where blot was cut). Human BPI (hBPI) was used as a positive control. All measurements are means ± SEM from biological replicates.

    Techniques Used: Enzyme-linked Immunosorbent Assay, MANN-WHITNEY, SDS Page, Western Blot, Positive Control

    Increased levels of plasma autoantibodies and IgG-bound BPI in CF airway samples. (A) IgG autoantibodies against BPI were quantified in plasma of PWCF (CF, n=30) or healthy controls (HC, n=37). A significant increase in the titre of BPI autoantibodies were detected in CF (p<0.0001, Mann-Whitney U test). Positivity was set as 10 U/ml as indicated by the hatched line. All CF samples were positive for BPI autoantibodies. Increased circulating IgG BPI antibody level in CF individuals determined by ELISA. (B) Plasma samples from HC (n=38), CF (n=28) and CF individuals receiving ivacaftor treatment (n=10). No difference in levels of circulating anti-BPI IgG autoantibodies between CF and CF individuals receiving ivacaftor treatment (p=0.39). (C) Representative Coomassie blue stained SDS gel of purified IgG from CF BAL. Protein G Sepharose was used to isolate IgG from BAL of Phe508del homozygous PWCF. Starting BAL sample (St), unbound material (Un) or purified bound IgG (Bd) with or without DTT reduction are presented. Purified IgG (150 kDa, closed arrow), and the heavy (50 kDa) and light chains (25 kDa) of IgG are indicated (open arrows) (1 representative images of n = 5 biological repeats). (D) Protein G Sepharose was used to isolate IgG-BPI complexes from CF BAL. Reactions were analyzed by immunoblotting for BPI positivity using a mouse monoclonal anti-BPI antibody. Starting BAL sample (St), unbound material (Un) or IgG-bound BPI (Bd) are presented. Human BPI (hBPI) was used as a positive control (55 kDa). A control immunoblot to ensure BPI specificity omitted primary antibody (right hand panel), with no immune-band apparent. 3 representative images of n=5 biological repeats.
    Figure Legend Snippet: Increased levels of plasma autoantibodies and IgG-bound BPI in CF airway samples. (A) IgG autoantibodies against BPI were quantified in plasma of PWCF (CF, n=30) or healthy controls (HC, n=37). A significant increase in the titre of BPI autoantibodies were detected in CF (p<0.0001, Mann-Whitney U test). Positivity was set as 10 U/ml as indicated by the hatched line. All CF samples were positive for BPI autoantibodies. Increased circulating IgG BPI antibody level in CF individuals determined by ELISA. (B) Plasma samples from HC (n=38), CF (n=28) and CF individuals receiving ivacaftor treatment (n=10). No difference in levels of circulating anti-BPI IgG autoantibodies between CF and CF individuals receiving ivacaftor treatment (p=0.39). (C) Representative Coomassie blue stained SDS gel of purified IgG from CF BAL. Protein G Sepharose was used to isolate IgG from BAL of Phe508del homozygous PWCF. Starting BAL sample (St), unbound material (Un) or purified bound IgG (Bd) with or without DTT reduction are presented. Purified IgG (150 kDa, closed arrow), and the heavy (50 kDa) and light chains (25 kDa) of IgG are indicated (open arrows) (1 representative images of n = 5 biological repeats). (D) Protein G Sepharose was used to isolate IgG-BPI complexes from CF BAL. Reactions were analyzed by immunoblotting for BPI positivity using a mouse monoclonal anti-BPI antibody. Starting BAL sample (St), unbound material (Un) or IgG-bound BPI (Bd) are presented. Human BPI (hBPI) was used as a positive control (55 kDa). A control immunoblot to ensure BPI specificity omitted primary antibody (right hand panel), with no immune-band apparent. 3 representative images of n=5 biological repeats.

    Techniques Used: MANN-WHITNEY, Enzyme-linked Immunosorbent Assay, Staining, SDS-Gel, Purification, Western Blot, Positive Control

    human bpi elisa kit  (Hycult Biotech)


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    Hycult Biotech human bpi elisa kit
    Human Bpi Elisa Kit, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    human bpi elisa kit  (Hycult Biotech)


    Bioz Verified Symbol Hycult Biotech is a verified supplier
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    Hycult Biotech human bpi elisa kit
    Human Bpi Elisa Kit, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 93 stars, based on 1 article reviews
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    Hycult Biotech plasma lipopolysaccharide binding protein
    Plasma Lipopolysaccharide Binding Protein, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Hycult Biotech human bpi concentrations
    Validation of OLFM4 expression at the transcriptional and protein level. ( A ) Expression of ten critical genes was compared between healthy controls, septic patients, and sepsis-related ARDS patients by quantitative real-time PCR. Differences between two groups were analyzed. * p < 0.05, ** p < 0.01 versus CT group, # p < 0.05 versus sepsis group. ( B , C and D ) Plasma OLFM4, LCN2 and <t>BPI</t> expressions were compared between healthy controls, septic patients, and sepsis-related ARDS patients <t>using</t> <t>ELISA</t> kit. ** p < 0.01 versus control group, *** p < 0.001 versus control group, # p < 0.05 versus sepsis group. ( E ) Analyses of ROC curves of plasma OLFM4, LCN2 and BPI expression. ROC curves were generated and the area under the ROC was used to compare plasma OLFM4, LCN2 and BPI expressions in the sepsis group and sepsis-related ARDS group.
    Human Bpi Concentrations, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Hycult Biotech elisa kit
    Validation of OLFM4 expression at the transcriptional and protein level. ( A ) Expression of ten critical genes was compared between healthy controls, septic patients, and sepsis-related ARDS patients by quantitative real-time PCR. Differences between two groups were analyzed. * p < 0.05, ** p < 0.01 versus CT group, # p < 0.05 versus sepsis group. ( B , C and D ) Plasma OLFM4, LCN2 <t>and</t> <t>BPI</t> expressions were compared between healthy controls, septic patients, and sepsis-related ARDS patients using <t>ELISA</t> kit. ** p < 0.01 versus control group, *** p < 0.001 versus control group, # p < 0.05 versus sepsis group. ( E ) Analyses of ROC curves of plasma OLFM4, LCN2 and BPI expression. ROC curves were generated and the area under the ROC was used to compare plasma OLFM4, LCN2 and BPI expressions in the sepsis group and sepsis-related ARDS group.
    Elisa Kit, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Hycult Biotech bpi
    LGM levels (mean ± SE) in individuals with healthy (n = 40) and unhealthy (n = 40) metabolic profiles in the pilot study.
    Bpi, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    LGM levels (mean ± SE) in individuals with healthy (n = 40) and unhealthy (n = 40) metabolic profiles in the pilot study.
    Hk314 02, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Validation of OLFM4 expression at the transcriptional and protein level. ( A ) Expression of ten critical genes was compared between healthy controls, septic patients, and sepsis-related ARDS patients by quantitative real-time PCR. Differences between two groups were analyzed. * p < 0.05, ** p < 0.01 versus CT group, # p < 0.05 versus sepsis group. ( B , C and D ) Plasma OLFM4, LCN2 and BPI expressions were compared between healthy controls, septic patients, and sepsis-related ARDS patients using ELISA kit. ** p < 0.01 versus control group, *** p < 0.001 versus control group, # p < 0.05 versus sepsis group. ( E ) Analyses of ROC curves of plasma OLFM4, LCN2 and BPI expression. ROC curves were generated and the area under the ROC was used to compare plasma OLFM4, LCN2 and BPI expressions in the sepsis group and sepsis-related ARDS group.

    Journal: Journal of Inflammation Research

    Article Title: OLFM4 Regulates Lung Epithelial Cell Function in Sepsis-Associated ARDS/ALI via LDHA-Mediated NF-κB Signaling

    doi: 10.2147/JIR.S335915

    Figure Lengend Snippet: Validation of OLFM4 expression at the transcriptional and protein level. ( A ) Expression of ten critical genes was compared between healthy controls, septic patients, and sepsis-related ARDS patients by quantitative real-time PCR. Differences between two groups were analyzed. * p < 0.05, ** p < 0.01 versus CT group, # p < 0.05 versus sepsis group. ( B , C and D ) Plasma OLFM4, LCN2 and BPI expressions were compared between healthy controls, septic patients, and sepsis-related ARDS patients using ELISA kit. ** p < 0.01 versus control group, *** p < 0.001 versus control group, # p < 0.05 versus sepsis group. ( E ) Analyses of ROC curves of plasma OLFM4, LCN2 and BPI expression. ROC curves were generated and the area under the ROC was used to compare plasma OLFM4, LCN2 and BPI expressions in the sepsis group and sepsis-related ARDS group.

    Article Snippet: The human BPI concentrations was measured by ELISA kit (HK314-01, HyCult, Uden, The Netherlands).

    Techniques: Expressing, Real-time Polymerase Chain Reaction, Enzyme-linked Immunosorbent Assay, Generated

    Validation of OLFM4 expression at the transcriptional and protein level. ( A ) Expression of ten critical genes was compared between healthy controls, septic patients, and sepsis-related ARDS patients by quantitative real-time PCR. Differences between two groups were analyzed. * p < 0.05, ** p < 0.01 versus CT group, # p < 0.05 versus sepsis group. ( B , C and D ) Plasma OLFM4, LCN2 and BPI expressions were compared between healthy controls, septic patients, and sepsis-related ARDS patients using ELISA kit. ** p < 0.01 versus control group, *** p < 0.001 versus control group, # p < 0.05 versus sepsis group. ( E ) Analyses of ROC curves of plasma OLFM4, LCN2 and BPI expression. ROC curves were generated and the area under the ROC was used to compare plasma OLFM4, LCN2 and BPI expressions in the sepsis group and sepsis-related ARDS group.

    Journal: Journal of Inflammation Research

    Article Title: OLFM4 Regulates Lung Epithelial Cell Function in Sepsis-Associated ARDS/ALI via LDHA-Mediated NF-κB Signaling

    doi: 10.2147/JIR.S335915

    Figure Lengend Snippet: Validation of OLFM4 expression at the transcriptional and protein level. ( A ) Expression of ten critical genes was compared between healthy controls, septic patients, and sepsis-related ARDS patients by quantitative real-time PCR. Differences between two groups were analyzed. * p < 0.05, ** p < 0.01 versus CT group, # p < 0.05 versus sepsis group. ( B , C and D ) Plasma OLFM4, LCN2 and BPI expressions were compared between healthy controls, septic patients, and sepsis-related ARDS patients using ELISA kit. ** p < 0.01 versus control group, *** p < 0.001 versus control group, # p < 0.05 versus sepsis group. ( E ) Analyses of ROC curves of plasma OLFM4, LCN2 and BPI expression. ROC curves were generated and the area under the ROC was used to compare plasma OLFM4, LCN2 and BPI expressions in the sepsis group and sepsis-related ARDS group.

    Article Snippet: The human BPI concentrations was measured by ELISA kit (HK314-01, HyCult, Uden, The Netherlands).

    Techniques: Expressing, Real-time Polymerase Chain Reaction, Enzyme-linked Immunosorbent Assay, Generated

    LGM levels (mean ± SE) in individuals with healthy (n = 40) and unhealthy (n = 40) metabolic profiles in the pilot study.

    Journal: PLoS ONE

    Article Title: Identification of leaky gut-related markers as indicators of metabolic health in Dutch adults: The Nutrition Questionnaires plus (NQplus) study

    doi: 10.1371/journal.pone.0252936

    Figure Lengend Snippet: LGM levels (mean ± SE) in individuals with healthy (n = 40) and unhealthy (n = 40) metabolic profiles in the pilot study.

    Article Snippet: Enzyme-linked immunosorbent assay was used to measure zonulin (K5601; Immundiagnostik AG, Bensheim, Germany) in serum as well as LBP (HK315-02; Hycult Biotech, Uden, Netherlands), EndoCAb IgM (HK504-IgM; Hycult Biotech), EndoCAb IgG (HK504-IgG; Hycult Biotech), EndoCAb IgA (HK504-IgA; Hycult Biotech), BPI (HK314-02; Hycult Biotech), sCD14 (HK320-02; Hycult Biotech), and PG (ABIN1116409; Antibodies-Online, Atlanta, GA, USA) in EDTA plasma according to the manufacturer’s protocol.

    Techniques: