Journal: Journal of immunology (Baltimore, Md. : 1950)
Article Title: Malaria inhibits surface expression of complement receptor-1 in monocyte/macrophages causing decreased immunecomplex internalization
doi: 10.4049/jimmunol.1103812
Figure Lengend Snippet: A) ICs (IgM and IgG), detected using an indirect ELISA coated with C1q. B–E) CR1 surface expression levels on macrophages CD16+CD10− (B), B cells CD19+CD138− (C), plasmatic cells CD19−CD138+ (D) and neutrophils CD16+CD10+ (E) were analyzed in peripheral blood from healthy controls or patients during P. vivax and P. falciparum infections. Data are expressed as percentage of cells expressing high levels of CR1. * p < 0.05, ** p < 0.01 and *** p < 0.001, when the control group is compared with either P. falciparum or P. vivax infected groups by Mann-Whitney test.
Article Snippet: For human anti-C1q a modification of kit (Hycult, Biotech) was used.
Techniques: Indirect ELISA, Expressing, Infection, MANN-WHITNEY