par2 agonist  (Alomone Labs)


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    Structured Review

    Alomone Labs par2 agonist
    Par2 Agonist, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/par2 agonist/product/Alomone Labs
    Average 90 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    par2 agonist - by Bioz Stars, 2022-07
    90/100 stars

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    Alomone Labs anti nav1 5 polyclonal antibody
    Na v 1.5 contributes to invasive potential of colon cancer cells ( A ) The total number of invading SW620, SW480 and HT29 colon cancer cells was significantly reduced with 30 μM TTX compared to vehicle control. ( B ) siRNA-mediated knockdown of <t>SCN5A</t>
    Anti Nav1 5 Polyclonal Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti nav1 5 polyclonal antibody/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
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    93
    Alomone Labs guinea pig anti bdnf antibody
    <t>AGS</t> increases <t>BDNF</t> but not NGF gene expression in both Aβ treated and untreated cultures. Cultures were treated for 36 hr. with AGS-499 (200 nM) alone, Aβ (5 µM) alone, and Aβ (5 µM) in combination with AGS-499 (200 nM) or with its vehicle DMSO. AGS or DMSO treatments were renewed after 24 hr. Expression levels were quantified using RT-PCR and normalized to the untreated control (Control). ( a ) Relative BDNF gene expression in cultures (Mean ± SEM, n = 5 independent experiments), ANOVA test ***p
    Guinea Pig Anti Bdnf Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/guinea pig anti bdnf antibody/product/Alomone Labs
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    90
    Alomone Labs guinea pig anti hcn1
    Analyses of expression of the Cav2.3 protein in neuronal and nonneuronal cells or in cell membrane of the cells in dorsal root ganglia in vivo. Representative images to demonstrate expression of Cav2.3 in mouse DRG and colabeling with PGP9.5-positive neuronal cells (A), GFAP-positive satellite cells (B) and with <t>HCN1</t> (hyperpolarization-activated cyclic nucleotide-gated) channel in the cell membrane (C). Observed colocalization is highlighted with white arrows. Quantification of coexpression of each neuronal subtype with the Cav2.3 expressing neurons is shown in panel D. Scale bars represent 50 µm in all panels. Tissue samples from 3 independent mice were analyzed.
    Guinea Pig Anti Hcn1, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/guinea pig anti hcn1/product/Alomone Labs
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    Alomone Labs par2 agonist
    Analyses of expression of the Cav2.3 protein in neuronal and nonneuronal cells or in cell membrane of the cells in dorsal root ganglia in vivo. Representative images to demonstrate expression of Cav2.3 in mouse DRG and colabeling with PGP9.5-positive neuronal cells (A), GFAP-positive satellite cells (B) and with <t>HCN1</t> (hyperpolarization-activated cyclic nucleotide-gated) channel in the cell membrane (C). Observed colocalization is highlighted with white arrows. Quantification of coexpression of each neuronal subtype with the Cav2.3 expressing neurons is shown in panel D. Scale bars represent 50 µm in all panels. Tissue samples from 3 independent mice were analyzed.
    Par2 Agonist, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/par2 agonist/product/Alomone Labs
    Average 90 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    par2 agonist - by Bioz Stars, 2022-07
    90/100 stars
      Buy from Supplier

    Image Search Results


    Na v 1.5 contributes to invasive potential of colon cancer cells ( A ) The total number of invading SW620, SW480 and HT29 colon cancer cells was significantly reduced with 30 μM TTX compared to vehicle control. ( B ) siRNA-mediated knockdown of SCN5A

    Journal: Cancer research

    Article Title: Voltage-gated Na+ channel SCN5A is a key regulator of a gene transcriptional network that controls colon cancer invasion

    doi: 10.1158/0008-5472.CAN-10-1169

    Figure Lengend Snippet: Na v 1.5 contributes to invasive potential of colon cancer cells ( A ) The total number of invading SW620, SW480 and HT29 colon cancer cells was significantly reduced with 30 μM TTX compared to vehicle control. ( B ) siRNA-mediated knockdown of SCN5A

    Article Snippet: Sections were incubated with anti-Nav1.5 polyclonal antibody (1:100) (Alomone labs) for three hours, followed by one hour with HRP labeled polymer conjugated anti-rabbit secondary antibody.

    Techniques:

    SCN5A and predicted network genes involved in the invasive potential of HT29 cells. siRNA-mediated knockdown of individual genes proposed to be involved in the invasion network leads to a loss of invasion. ( A ) qRT-PCR was performed to validate mRNA knockdowns

    Journal: Cancer research

    Article Title: Voltage-gated Na+ channel SCN5A is a key regulator of a gene transcriptional network that controls colon cancer invasion

    doi: 10.1158/0008-5472.CAN-10-1169

    Figure Lengend Snippet: SCN5A and predicted network genes involved in the invasive potential of HT29 cells. siRNA-mediated knockdown of individual genes proposed to be involved in the invasion network leads to a loss of invasion. ( A ) qRT-PCR was performed to validate mRNA knockdowns

    Article Snippet: Sections were incubated with anti-Nav1.5 polyclonal antibody (1:100) (Alomone labs) for three hours, followed by one hour with HRP labeled polymer conjugated anti-rabbit secondary antibody.

    Techniques: Quantitative RT-PCR

    AGS increases BDNF but not NGF gene expression in both Aβ treated and untreated cultures. Cultures were treated for 36 hr. with AGS-499 (200 nM) alone, Aβ (5 µM) alone, and Aβ (5 µM) in combination with AGS-499 (200 nM) or with its vehicle DMSO. AGS or DMSO treatments were renewed after 24 hr. Expression levels were quantified using RT-PCR and normalized to the untreated control (Control). ( a ) Relative BDNF gene expression in cultures (Mean ± SEM, n = 5 independent experiments), ANOVA test ***p

    Journal: Scientific Reports

    Article Title: Telomerase increasing compound protects hippocampal neurons from amyloid beta toxicity by enhancing the expression of neurotrophins and plasticity related genes

    doi: 10.1038/s41598-019-54741-7

    Figure Lengend Snippet: AGS increases BDNF but not NGF gene expression in both Aβ treated and untreated cultures. Cultures were treated for 36 hr. with AGS-499 (200 nM) alone, Aβ (5 µM) alone, and Aβ (5 µM) in combination with AGS-499 (200 nM) or with its vehicle DMSO. AGS or DMSO treatments were renewed after 24 hr. Expression levels were quantified using RT-PCR and normalized to the untreated control (Control). ( a ) Relative BDNF gene expression in cultures (Mean ± SEM, n = 5 independent experiments), ANOVA test ***p

    Article Snippet: The brain slices (5 μΜ) derived from vehicle (DMSO) and AGS-499 treated mice were subjected to immunofluorescence analysis using as first antibody: Guinea pig anti BDNF-antibody (1:100, # AGP-021, alomono labs, Israel) or anti-beta catenin antibody (1:100, β-Catenin (6B3) Rabbit mAb #9582, Cell Signaling technology, Danvers, MA, USA).

    Techniques: Expressing, Reverse Transcription Polymerase Chain Reaction

    Analyses of expression of the Cav2.3 protein in neuronal and nonneuronal cells or in cell membrane of the cells in dorsal root ganglia in vivo. Representative images to demonstrate expression of Cav2.3 in mouse DRG and colabeling with PGP9.5-positive neuronal cells (A), GFAP-positive satellite cells (B) and with HCN1 (hyperpolarization-activated cyclic nucleotide-gated) channel in the cell membrane (C). Observed colocalization is highlighted with white arrows. Quantification of coexpression of each neuronal subtype with the Cav2.3 expressing neurons is shown in panel D. Scale bars represent 50 µm in all panels. Tissue samples from 3 independent mice were analyzed.

    Journal: Pain

    Article Title: miR-34c-5p functions as pronociceptive microRNA in cancer pain by targeting Cav2.3 containing calcium channels

    doi: 10.1097/j.pain.0000000000000971

    Figure Lengend Snippet: Analyses of expression of the Cav2.3 protein in neuronal and nonneuronal cells or in cell membrane of the cells in dorsal root ganglia in vivo. Representative images to demonstrate expression of Cav2.3 in mouse DRG and colabeling with PGP9.5-positive neuronal cells (A), GFAP-positive satellite cells (B) and with HCN1 (hyperpolarization-activated cyclic nucleotide-gated) channel in the cell membrane (C). Observed colocalization is highlighted with white arrows. Quantification of coexpression of each neuronal subtype with the Cav2.3 expressing neurons is shown in panel D. Scale bars represent 50 µm in all panels. Tissue samples from 3 independent mice were analyzed.

    Article Snippet: Primary antibodies used for IF are Guinea pig anti-PGP9.5 (1:100 dilution, 14104, Neuromics, Edina, MN), Guinea pig anti-HCN1 (1:100, Alomone Labs, AGP203) rabbit anti-Cav2.3 antibody (1:80, Alomone Labs, ACC-006), Biotinylated-Isolectin B4 (1:100; B-1205, Vector, Burlingame, CA), Guinea pig Substance P (1:150; Neuromics GP14103), Anti-GFAP (1:500; NeuroMab clone N206A/8, UC Davis, Davis, CA) and Chicken anti-NF200 (1:500; Neuromics CH23015).

    Techniques: Expressing, In Vivo, Mouse Assay