Gyki 53655, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 85/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 85 stars, based on 1 article reviews
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1) Product Images from "DIVERSE MECHANISMS UNDERLIE GLYCINERGIC FEEDBACK TRANSMISSION ONTO ROD BIPOLAR CELLS IN RAT RETINA"
Article Title: DIVERSE MECHANISMS UNDERLIE GLYCINERGIC FEEDBACK TRANSMISSION ONTO ROD BIPOLAR CELLS IN RAT RETINA
Figure Legend Snippet: Different glutamate receptors mediate activation of glycinergic amacrine cells. A, Feedback IPSCs were reduced by the non-NMDAR antagonist NBQX (25 μM). B, Feedback IPSC also were reduced by the NMDAR antagonist CPP (10 μM) and eliminated by co-application with NBQX (25 μm). C, Feedback IPSCs were reduced by application of the AMPAR antagonist GYKI 53655 (50 μm); co-application of CPP reduced the IPSC further, but a small component remained. D, The Ca2+-permeable AMPARs antagonist philanthotoxin (PhTx) did not reduce IPSCs, but CPP and NBQX eliminated them. D, Summarized drug effects (mean ± SD) on IPSCs; ND: experiment not done. Experiments were performed in the presence of GABAR antagonists (SR95531 and TPMPA) and DHT.
Techniques Used: Activation Assay