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fluconazole  (Gold Biotechnology Inc)


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    Structured Review

    Gold Biotechnology Inc fluconazole
    (A) Dose-response curves of C. auris to the antifungals caspofungin, <t>fluconazole,</t> and amphotericin B at the indicated temperatures. (B) Dose-response curves of indicated C. auris assembly chaperone mutants show hypersensitivity to MG-132 at all tested temperatures. (C) Dose-response curves of C. auris , C. albicans , and S. cerevisiae to Bortezomib at the indicated temperatures. Growth measured by OD 600 at each drug concentration is normalized to the growth of each strain in the absence of drug to determine relative growth. Data show mean ± standard deviation across 3 biological replicates. Statistical significance among different groups was calculated using one-way ANOVA, with Dunnett’s post hoc tests for multiple comparisons. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001; n.s., p > 0.05.
    Fluconazole, supplied by Gold Biotechnology Inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/fluconazole/product/Gold Biotechnology Inc
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    Images

    1) Product Images from "Deep homology and design of proteasome chaperone proteins in Candida auris"

    Article Title: Deep homology and design of proteasome chaperone proteins in Candida auris

    Journal: bioRxiv

    doi: 10.1101/2025.05.14.654010

    (A) Dose-response curves of C. auris to the antifungals caspofungin, fluconazole, and amphotericin B at the indicated temperatures. (B) Dose-response curves of indicated C. auris assembly chaperone mutants show hypersensitivity to MG-132 at all tested temperatures. (C) Dose-response curves of C. auris , C. albicans , and S. cerevisiae to Bortezomib at the indicated temperatures. Growth measured by OD 600 at each drug concentration is normalized to the growth of each strain in the absence of drug to determine relative growth. Data show mean ± standard deviation across 3 biological replicates. Statistical significance among different groups was calculated using one-way ANOVA, with Dunnett’s post hoc tests for multiple comparisons. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001; n.s., p > 0.05.
    Figure Legend Snippet: (A) Dose-response curves of C. auris to the antifungals caspofungin, fluconazole, and amphotericin B at the indicated temperatures. (B) Dose-response curves of indicated C. auris assembly chaperone mutants show hypersensitivity to MG-132 at all tested temperatures. (C) Dose-response curves of C. auris , C. albicans , and S. cerevisiae to Bortezomib at the indicated temperatures. Growth measured by OD 600 at each drug concentration is normalized to the growth of each strain in the absence of drug to determine relative growth. Data show mean ± standard deviation across 3 biological replicates. Statistical significance among different groups was calculated using one-way ANOVA, with Dunnett’s post hoc tests for multiple comparisons. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001; n.s., p > 0.05.

    Techniques Used: Concentration Assay, Standard Deviation



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    (A) Dose-response curves of C. auris to the antifungals caspofungin, <t>fluconazole,</t> and amphotericin B at the indicated temperatures. (B) Dose-response curves of indicated C. auris assembly chaperone mutants show hypersensitivity to MG-132 at all tested temperatures. (C) Dose-response curves of C. auris , C. albicans , and S. cerevisiae to Bortezomib at the indicated temperatures. Growth measured by OD 600 at each drug concentration is normalized to the growth of each strain in the absence of drug to determine relative growth. Data show mean ± standard deviation across 3 biological replicates. Statistical significance among different groups was calculated using one-way ANOVA, with Dunnett’s post hoc tests for multiple comparisons. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001; n.s., p > 0.05.
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    (A) Dose-response curves of C. auris to the antifungals caspofungin, <t>fluconazole,</t> and amphotericin B at the indicated temperatures. (B) Dose-response curves of indicated C. auris assembly chaperone mutants show hypersensitivity to MG-132 at all tested temperatures. (C) Dose-response curves of C. auris , C. albicans , and S. cerevisiae to Bortezomib at the indicated temperatures. Growth measured by OD 600 at each drug concentration is normalized to the growth of each strain in the absence of drug to determine relative growth. Data show mean ± standard deviation across 3 biological replicates. Statistical significance among different groups was calculated using one-way ANOVA, with Dunnett’s post hoc tests for multiple comparisons. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001; n.s., p > 0.05.
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    (A) Dose-response curves of C. auris to the antifungals caspofungin, <t>fluconazole,</t> and amphotericin B at the indicated temperatures. (B) Dose-response curves of indicated C. auris assembly chaperone mutants show hypersensitivity to MG-132 at all tested temperatures. (C) Dose-response curves of C. auris , C. albicans , and S. cerevisiae to Bortezomib at the indicated temperatures. Growth measured by OD 600 at each drug concentration is normalized to the growth of each strain in the absence of drug to determine relative growth. Data show mean ± standard deviation across 3 biological replicates. Statistical significance among different groups was calculated using one-way ANOVA, with Dunnett’s post hoc tests for multiple comparisons. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001; n.s., p > 0.05.
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    (A) Dose-response curves of C. auris to the antifungals caspofungin, <t>fluconazole,</t> and amphotericin B at the indicated temperatures. (B) Dose-response curves of indicated C. auris assembly chaperone mutants show hypersensitivity to MG-132 at all tested temperatures. (C) Dose-response curves of C. auris , C. albicans , and S. cerevisiae to Bortezomib at the indicated temperatures. Growth measured by OD 600 at each drug concentration is normalized to the growth of each strain in the absence of drug to determine relative growth. Data show mean ± standard deviation across 3 biological replicates. Statistical significance among different groups was calculated using one-way ANOVA, with Dunnett’s post hoc tests for multiple comparisons. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001; n.s., p > 0.05.
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    (A) Dose-response curves of C. auris to the antifungals caspofungin, <t>fluconazole,</t> and amphotericin B at the indicated temperatures. (B) Dose-response curves of indicated C. auris assembly chaperone mutants show hypersensitivity to MG-132 at all tested temperatures. (C) Dose-response curves of C. auris , C. albicans , and S. cerevisiae to Bortezomib at the indicated temperatures. Growth measured by OD 600 at each drug concentration is normalized to the growth of each strain in the absence of drug to determine relative growth. Data show mean ± standard deviation across 3 biological replicates. Statistical significance among different groups was calculated using one-way ANOVA, with Dunnett’s post hoc tests for multiple comparisons. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001; n.s., p > 0.05.
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    Image Search Results


    (A) Dose-response curves of C. auris to the antifungals caspofungin, fluconazole, and amphotericin B at the indicated temperatures. (B) Dose-response curves of indicated C. auris assembly chaperone mutants show hypersensitivity to MG-132 at all tested temperatures. (C) Dose-response curves of C. auris , C. albicans , and S. cerevisiae to Bortezomib at the indicated temperatures. Growth measured by OD 600 at each drug concentration is normalized to the growth of each strain in the absence of drug to determine relative growth. Data show mean ± standard deviation across 3 biological replicates. Statistical significance among different groups was calculated using one-way ANOVA, with Dunnett’s post hoc tests for multiple comparisons. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001; n.s., p > 0.05.

    Journal: bioRxiv

    Article Title: Deep homology and design of proteasome chaperone proteins in Candida auris

    doi: 10.1101/2025.05.14.654010

    Figure Lengend Snippet: (A) Dose-response curves of C. auris to the antifungals caspofungin, fluconazole, and amphotericin B at the indicated temperatures. (B) Dose-response curves of indicated C. auris assembly chaperone mutants show hypersensitivity to MG-132 at all tested temperatures. (C) Dose-response curves of C. auris , C. albicans , and S. cerevisiae to Bortezomib at the indicated temperatures. Growth measured by OD 600 at each drug concentration is normalized to the growth of each strain in the absence of drug to determine relative growth. Data show mean ± standard deviation across 3 biological replicates. Statistical significance among different groups was calculated using one-way ANOVA, with Dunnett’s post hoc tests for multiple comparisons. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001; n.s., p > 0.05.

    Article Snippet: Tested fluconazole (Cayman Chemical, 11594), caspofungin (GoldBio, C-520-10), and amphotericin B (GoldBio, A-560-250), concentrations ranged from 0.04-64 µg/mL, 0.08-80 ng/mL, and 0.04-64 µg/mL, respectively.

    Techniques: Concentration Assay, Standard Deviation