k252a  (Alomone Labs)


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    Structured Review

    Alomone Labs k252a
    Mechanisms of NGF action. A , Example traces showing mEPSCs from cholinergic neurons grown in control (left) versus NGF condition (right). B , Kolmogorov–Smirnov graphs illustrate that NGF decreased the interevent interval (left) without altering the amplitude (right) of mEPSCs in cholinergic neurons ( n = 2 control, 3 NGF neurons). C , D , MLR2/3 (p75 NTR -antibodies), but not <t>K252a</t> (trk inhibitor), prevented NGF-induced increase in the amplitude of EPSCs in cholinergic neurons. n.s., p > 0.05. * p
    K252a, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/k252a/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    k252a - by Bioz Stars, 2022-05
    93/100 stars

    Images

    1) Product Images from "Chronic Exposure to Nerve Growth Factor Increases Acetylcholine and Glutamate Release from Cholinergic Neurons of the Rat Medial Septum and Diagonal Band of Broca via Mechanisms Mediated by p75NTR"

    Article Title: Chronic Exposure to Nerve Growth Factor Increases Acetylcholine and Glutamate Release from Cholinergic Neurons of the Rat Medial Septum and Diagonal Band of Broca via Mechanisms Mediated by p75NTR

    Journal: The Journal of Neuroscience

    doi: 10.1523/JNEUROSCI.4851-07.2008

    Mechanisms of NGF action. A , Example traces showing mEPSCs from cholinergic neurons grown in control (left) versus NGF condition (right). B , Kolmogorov–Smirnov graphs illustrate that NGF decreased the interevent interval (left) without altering the amplitude (right) of mEPSCs in cholinergic neurons ( n = 2 control, 3 NGF neurons). C , D , MLR2/3 (p75 NTR -antibodies), but not K252a (trk inhibitor), prevented NGF-induced increase in the amplitude of EPSCs in cholinergic neurons. n.s., p > 0.05. * p
    Figure Legend Snippet: Mechanisms of NGF action. A , Example traces showing mEPSCs from cholinergic neurons grown in control (left) versus NGF condition (right). B , Kolmogorov–Smirnov graphs illustrate that NGF decreased the interevent interval (left) without altering the amplitude (right) of mEPSCs in cholinergic neurons ( n = 2 control, 3 NGF neurons). C , D , MLR2/3 (p75 NTR -antibodies), but not K252a (trk inhibitor), prevented NGF-induced increase in the amplitude of EPSCs in cholinergic neurons. n.s., p > 0.05. * p

    Techniques Used:

    NGF increased both acetylcholine and glutamate transmission from cholinergic neurons via p75 NTR . A , Cholinergic neurons exposed to NGF displayed larger nicotinic and glutamatergic currents than controls. B , C , K252a did not affect NGF-induced increases in nicotinic or glutamatergic currents. D , E , MLR2/3 significantly reduced the effects of NGF on nicotinic and glutamatergic currents. F , G , Cholinergic neurons grown in NGF had significantly larger cell bodies compared with controls. The effect of NGF on soma size was blocked by K252a, but not by MLR2/3. n.s., p > 0.05. * p
    Figure Legend Snippet: NGF increased both acetylcholine and glutamate transmission from cholinergic neurons via p75 NTR . A , Cholinergic neurons exposed to NGF displayed larger nicotinic and glutamatergic currents than controls. B , C , K252a did not affect NGF-induced increases in nicotinic or glutamatergic currents. D , E , MLR2/3 significantly reduced the effects of NGF on nicotinic and glutamatergic currents. F , G , Cholinergic neurons grown in NGF had significantly larger cell bodies compared with controls. The effect of NGF on soma size was blocked by K252a, but not by MLR2/3. n.s., p > 0.05. * p

    Techniques Used: Transmission Assay

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    Alomone Labs k252a
    Mechanisms of NGF action. A , Example traces showing mEPSCs from cholinergic neurons grown in control (left) versus NGF condition (right). B , Kolmogorov–Smirnov graphs illustrate that NGF decreased the interevent interval (left) without altering the amplitude (right) of mEPSCs in cholinergic neurons ( n = 2 control, 3 NGF neurons). C , D , MLR2/3 (p75 NTR -antibodies), but not <t>K252a</t> (trk inhibitor), prevented NGF-induced increase in the amplitude of EPSCs in cholinergic neurons. n.s., p > 0.05. * p
    K252a, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/k252a/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    k252a - by Bioz Stars, 2022-05
    93/100 stars
      Buy from Supplier

    86
    Alomone Labs horse anti mouse igg conjugated to fitc
    Mechanisms of NGF action. A , Example traces showing mEPSCs from cholinergic neurons grown in control (left) versus NGF condition (right). B , Kolmogorov–Smirnov graphs illustrate that NGF decreased the interevent interval (left) without altering the amplitude (right) of mEPSCs in cholinergic neurons ( n = 2 control, 3 NGF neurons). C , D , MLR2/3 (p75 NTR -antibodies), but not <t>K252a</t> (trk inhibitor), prevented NGF-induced increase in the amplitude of EPSCs in cholinergic neurons. n.s., p > 0.05. * p
    Horse Anti Mouse Igg Conjugated To Fitc, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/horse anti mouse igg conjugated to fitc/product/Alomone Labs
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    horse anti mouse igg conjugated to fitc - by Bioz Stars, 2022-05
    86/100 stars
      Buy from Supplier

    Image Search Results


    Mechanisms of NGF action. A , Example traces showing mEPSCs from cholinergic neurons grown in control (left) versus NGF condition (right). B , Kolmogorov–Smirnov graphs illustrate that NGF decreased the interevent interval (left) without altering the amplitude (right) of mEPSCs in cholinergic neurons ( n = 2 control, 3 NGF neurons). C , D , MLR2/3 (p75 NTR -antibodies), but not K252a (trk inhibitor), prevented NGF-induced increase in the amplitude of EPSCs in cholinergic neurons. n.s., p > 0.05. * p

    Journal: The Journal of Neuroscience

    Article Title: Chronic Exposure to Nerve Growth Factor Increases Acetylcholine and Glutamate Release from Cholinergic Neurons of the Rat Medial Septum and Diagonal Band of Broca via Mechanisms Mediated by p75NTR

    doi: 10.1523/JNEUROSCI.4851-07.2008

    Figure Lengend Snippet: Mechanisms of NGF action. A , Example traces showing mEPSCs from cholinergic neurons grown in control (left) versus NGF condition (right). B , Kolmogorov–Smirnov graphs illustrate that NGF decreased the interevent interval (left) without altering the amplitude (right) of mEPSCs in cholinergic neurons ( n = 2 control, 3 NGF neurons). C , D , MLR2/3 (p75 NTR -antibodies), but not K252a (trk inhibitor), prevented NGF-induced increase in the amplitude of EPSCs in cholinergic neurons. n.s., p > 0.05. * p

    Article Snippet: We found that NGF indeed increased the soma size of cholinergic neurons ( p < 0.05) and that this effect was blocked by K252a ( p < 0.05) ( F ), but not by MLR2/3 ( p > 0.05) ( G ), indicating that the effect of NGF on soma size was mediated by trkA.

    Techniques:

    NGF increased both acetylcholine and glutamate transmission from cholinergic neurons via p75 NTR . A , Cholinergic neurons exposed to NGF displayed larger nicotinic and glutamatergic currents than controls. B , C , K252a did not affect NGF-induced increases in nicotinic or glutamatergic currents. D , E , MLR2/3 significantly reduced the effects of NGF on nicotinic and glutamatergic currents. F , G , Cholinergic neurons grown in NGF had significantly larger cell bodies compared with controls. The effect of NGF on soma size was blocked by K252a, but not by MLR2/3. n.s., p > 0.05. * p

    Journal: The Journal of Neuroscience

    Article Title: Chronic Exposure to Nerve Growth Factor Increases Acetylcholine and Glutamate Release from Cholinergic Neurons of the Rat Medial Septum and Diagonal Band of Broca via Mechanisms Mediated by p75NTR

    doi: 10.1523/JNEUROSCI.4851-07.2008

    Figure Lengend Snippet: NGF increased both acetylcholine and glutamate transmission from cholinergic neurons via p75 NTR . A , Cholinergic neurons exposed to NGF displayed larger nicotinic and glutamatergic currents than controls. B , C , K252a did not affect NGF-induced increases in nicotinic or glutamatergic currents. D , E , MLR2/3 significantly reduced the effects of NGF on nicotinic and glutamatergic currents. F , G , Cholinergic neurons grown in NGF had significantly larger cell bodies compared with controls. The effect of NGF on soma size was blocked by K252a, but not by MLR2/3. n.s., p > 0.05. * p

    Article Snippet: We found that NGF indeed increased the soma size of cholinergic neurons ( p < 0.05) and that this effect was blocked by K252a ( p < 0.05) ( F ), but not by MLR2/3 ( p > 0.05) ( G ), indicating that the effect of NGF on soma size was mediated by trkA.

    Techniques: Transmission Assay