retigabine  (Alomone Labs)


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    Alomone Labs retigabine
    The Kv7 channel positive modulator, <t>retigabine,</t> reduced ethanol consumption in high-drinking, but not low-drinking male C57BL/6J mice ( A ) Average weekly ethanol consumption and ( B ) intra-strain variability of 24 hr ethanol consumption in C57BL/6J mice during week 7 of the intermittent access model. ( C ) Despite the large between-subjects variation, the coefficient of variance during 7 weeks of access to ethanol in the intermittent model indicates increased within-subject stability (n = 19 mice, * p
    Retigabine, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/retigabine/product/Alomone Labs
    Average 94 stars, based on 3 article reviews
    Price from $9.99 to $1999.99
    retigabine - by Bioz Stars, 2022-12
    94/100 stars

    Images

    1) Product Images from "Differential Potassium Channel Gene Regulation in BXD Mice Reveals Novel Targets for Pharmacogenetic Therapies to Reduce Heavy Alcohol Drinking"

    Article Title: Differential Potassium Channel Gene Regulation in BXD Mice Reveals Novel Targets for Pharmacogenetic Therapies to Reduce Heavy Alcohol Drinking

    Journal: Alcohol (Fayetteville, N.Y.)

    doi: 10.1016/j.alcohol.2016.05.007

    The Kv7 channel positive modulator, retigabine, reduced ethanol consumption in high-drinking, but not low-drinking male C57BL/6J mice ( A ) Average weekly ethanol consumption and ( B ) intra-strain variability of 24 hr ethanol consumption in C57BL/6J mice during week 7 of the intermittent access model. ( C ) Despite the large between-subjects variation, the coefficient of variance during 7 weeks of access to ethanol in the intermittent model indicates increased within-subject stability (n = 19 mice, * p
    Figure Legend Snippet: The Kv7 channel positive modulator, retigabine, reduced ethanol consumption in high-drinking, but not low-drinking male C57BL/6J mice ( A ) Average weekly ethanol consumption and ( B ) intra-strain variability of 24 hr ethanol consumption in C57BL/6J mice during week 7 of the intermittent access model. ( C ) Despite the large between-subjects variation, the coefficient of variance during 7 weeks of access to ethanol in the intermittent model indicates increased within-subject stability (n = 19 mice, * p

    Techniques Used: Mouse Assay

    2) Product Images from "Differential Potassium Channel Gene Regulation in BXD Mice Reveals Novel Targets for Pharmacogenetic Therapies to Reduce Heavy Alcohol Drinking"

    Article Title: Differential Potassium Channel Gene Regulation in BXD Mice Reveals Novel Targets for Pharmacogenetic Therapies to Reduce Heavy Alcohol Drinking

    Journal: Alcohol (Fayetteville, N.Y.)

    doi: 10.1016/j.alcohol.2016.05.007

    The Kv7 channel positive modulator, retigabine, reduced ethanol consumption in high-drinking, but not low-drinking male C57BL/6J mice ( A ) Average weekly ethanol consumption and ( B ) intra-strain variability of 24 hr ethanol consumption in C57BL/6J mice during week 7 of the intermittent access model. ( C ) Despite the large between-subjects variation, the coefficient of variance during 7 weeks of access to ethanol in the intermittent model indicates increased within-subject stability (n = 19 mice, * p
    Figure Legend Snippet: The Kv7 channel positive modulator, retigabine, reduced ethanol consumption in high-drinking, but not low-drinking male C57BL/6J mice ( A ) Average weekly ethanol consumption and ( B ) intra-strain variability of 24 hr ethanol consumption in C57BL/6J mice during week 7 of the intermittent access model. ( C ) Despite the large between-subjects variation, the coefficient of variance during 7 weeks of access to ethanol in the intermittent model indicates increased within-subject stability (n = 19 mice, * p

    Techniques Used: Mouse Assay

    3) Product Images from "Hyper-SUMOylation of the Kv7 Potassium Channel Diminishes the M-Current Leading to Seizures and Sudden Death"

    Article Title: Hyper-SUMOylation of the Kv7 Potassium Channel Diminishes the M-Current Leading to Seizures and Sudden Death

    Journal: Neuron

    doi: 10.1016/j.neuron.2014.07.042

    Prevention of Acoustics-Induced Seizures and AV Block in SENP2 fxN/fxN Mice with Retigabine
    Figure Legend Snippet: Prevention of Acoustics-Induced Seizures and AV Block in SENP2 fxN/fxN Mice with Retigabine

    Techniques Used: Blocking Assay, Mouse Assay

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  • News
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  • 94
    Alomone Labs retigabine
    The Kv7 channel positive modulator, <t>retigabine,</t> reduced ethanol consumption in high-drinking, but not low-drinking male C57BL/6J mice ( A ) Average weekly ethanol consumption and ( B ) intra-strain variability of 24 hr ethanol consumption in C57BL/6J mice during week 7 of the intermittent access model. ( C ) Despite the large between-subjects variation, the coefficient of variance during 7 weeks of access to ethanol in the intermittent model indicates increased within-subject stability (n = 19 mice, * p
    Retigabine, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/retigabine/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    retigabine - by Bioz Stars, 2022-12
    94/100 stars
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    The Kv7 channel positive modulator, retigabine, reduced ethanol consumption in high-drinking, but not low-drinking male C57BL/6J mice ( A ) Average weekly ethanol consumption and ( B ) intra-strain variability of 24 hr ethanol consumption in C57BL/6J mice during week 7 of the intermittent access model. ( C ) Despite the large between-subjects variation, the coefficient of variance during 7 weeks of access to ethanol in the intermittent model indicates increased within-subject stability (n = 19 mice, * p

    Journal: Alcohol (Fayetteville, N.Y.)

    Article Title: Differential Potassium Channel Gene Regulation in BXD Mice Reveals Novel Targets for Pharmacogenetic Therapies to Reduce Heavy Alcohol Drinking

    doi: 10.1016/j.alcohol.2016.05.007

    Figure Lengend Snippet: The Kv7 channel positive modulator, retigabine, reduced ethanol consumption in high-drinking, but not low-drinking male C57BL/6J mice ( A ) Average weekly ethanol consumption and ( B ) intra-strain variability of 24 hr ethanol consumption in C57BL/6J mice during week 7 of the intermittent access model. ( C ) Despite the large between-subjects variation, the coefficient of variance during 7 weeks of access to ethanol in the intermittent model indicates increased within-subject stability (n = 19 mice, * p

    Article Snippet: On test days, mice were injected with retigabine (RTG, dihydrochloride, Alomone Labs; 0, 5, 10 mg/kg – doses reflect the base, IP, 10 ml/kg in sterile saline) approximately 30 min prior to bottle access in a repeated measures fashion (i.e., each animal received each dose across a 3 week testing period in a counterbalanced order).

    Techniques: Mouse Assay

    Prevention of Acoustics-Induced Seizures and AV Block in SENP2 fxN/fxN Mice with Retigabine

    Journal: Neuron

    Article Title: Hyper-SUMOylation of the Kv7 Potassium Channel Diminishes the M-Current Leading to Seizures and Sudden Death

    doi: 10.1016/j.neuron.2014.07.042

    Figure Lengend Snippet: Prevention of Acoustics-Induced Seizures and AV Block in SENP2 fxN/fxN Mice with Retigabine

    Article Snippet: SENP2fxN/fxN mice (6 weeks old) were administrated atropine (1 mg/kg; Sigma) or propranolol (4 mg/kg; Sigma) for selective parasympathetic or sympathetic blockade and retigabine (10 mg/kg; Alomone labs) for seizure blockade.

    Techniques: Blocking Assay, Mouse Assay