kt5720 (Alomone Labs)


Structured Review

Kt5720, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/kt5720/product/Alomone Labs
Average 90 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
1) Product Images from "Phase-Dependent Molecular Requirements for Memory Reconsolidation: Differential Roles for Protein Synthesis and Protein Kinase A Activity"
Article Title: Phase-Dependent Molecular Requirements for Memory Reconsolidation: Differential Roles for Protein Synthesis and Protein Kinase A Activity
Journal: The Journal of Neuroscience
doi: 10.1523/JNEUROSCI.0890-06.2006

Figure Legend Snippet: PKA activity is required after memory retrieval at 6 but not 24 h after training for later memory expression. Six hours ( A ) or 24 h ( B ) after a single CS/US pairing (0 h), animals received a CS stimulation or no stimulation (no CS), followed 10 min later by an injection with either a PKA inhibitor (KT5720) or vehicle. In each group, baseline levels are defined by the mean feeding response level to the CS (line) ± SEM (gray band) of a group of animals handled in parallel ( n = 17). A , ANOVAs followed by pairwise post hoc tests reveal that the two groups ( n = 24 and 21) first tested at 6 h after training and 10 min before injection show significantly (*) elevated feeding responses to the CS compared with baseline level. At the second test, 24 h after training, one-way ANOVAs detected a source of significant difference. Of the four CS/US paired groups, only the group that received the CS at 6 h after training followed by KT5720 injection shows a feeding response to the CS that does not differ from baseline. A two-way ANOVA comparing the feeding responses to the CS of the four CS/US paired groups at 24 h detected a significant interaction of memory retrieval at 6 h and subsequent PKA inhibition. B , The two groups ( n = 17 and 20) first tested at 24 h after training and 10 min before injection show significantly (*) elevated feeding responses to the CS compared with the baseline level. At 42 h after training, one-way ANOVAs and multiple post hoc ).
Techniques Used: Activity Assay, Expressing, Injection, Inhibition
2) Product Images from "Different phases of long-term memory require distinct temporal patterns of PKA activity after single-trial classical conditioning"
Article Title: Different phases of long-term memory require distinct temporal patterns of PKA activity after single-trial classical conditioning
Journal: Learning & Memory
doi: 10.1101/lm.1088408

Figure Legend Snippet: A conserved functional PKA catalytic subunit (PKA C) is present in the Lymnaea CNS. ( A ) cAMP stimulates PKA C activity in Lymnaea nervous system extracts ( Ai ) and purified PKA fractions ( Aii ), which can be blocked by KT5720 or PKAI. The whole CNS data (mean ±SEM) come from experiments with single brains ( n = 19). *, P
Techniques Used: Functional Assay, Activity Assay, Purification
3) Product Images from "Different phases of long-term memory require distinct temporal patterns of PKA activity after single-trial classical conditioning"
Article Title: Different phases of long-term memory require distinct temporal patterns of PKA activity after single-trial classical conditioning
Journal: Learning & Memory
doi: 10.1101/lm.1088408

Figure Legend Snippet: A conserved functional PKA catalytic subunit (PKA C) is present in the Lymnaea CNS. ( A ) cAMP stimulates PKA C activity in Lymnaea nervous system extracts ( Ai ) and purified PKA fractions ( Aii ), which can be blocked by KT5720 or PKAI. The whole CNS data (mean ±SEM) come from experiments with single brains ( n = 19). *, P
Techniques Used: Functional Assay, Activity Assay, Purification
4) Product Images from "Different phases of long-term memory require distinct temporal patterns of PKA activity after single-trial classical conditioning"
Article Title: Different phases of long-term memory require distinct temporal patterns of PKA activity after single-trial classical conditioning
Journal: Learning & Memory
doi: 10.1101/lm.1088408

Figure Legend Snippet: A conserved functional PKA catalytic subunit (PKA C) is present in the Lymnaea CNS. ( A ) cAMP stimulates PKA C activity in Lymnaea nervous system extracts ( Ai ) and purified PKA fractions ( Aii ), which can be blocked by KT5720 or PKAI. The whole CNS data (mean ±SEM) come from experiments with single brains ( n = 19). *, P
Techniques Used: Functional Assay, Activity Assay, Purification
5) Product Images from "Different phases of long-term memory require distinct temporal patterns of PKA activity after single-trial classical conditioning"
Article Title: Different phases of long-term memory require distinct temporal patterns of PKA activity after single-trial classical conditioning
Journal: Learning & Memory
doi: 10.1101/lm.1088408

Figure Legend Snippet: A conserved functional PKA catalytic subunit (PKA C) is present in the Lymnaea CNS. ( A ) cAMP stimulates PKA C activity in Lymnaea nervous system extracts ( Ai ) and purified PKA fractions ( Aii ), which can be blocked by KT5720 or PKAI. The whole CNS data (mean ±SEM) come from experiments with single brains ( n = 19). *, P
Techniques Used: Functional Assay, Activity Assay, Purification