α dendrotoxin  (Alomone Labs)


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    Alomone Labs α dendrotoxin
    Properties of the first evoked spike in monkey and rat basket cells. A : first suprathreshold response to the depolarizing current was significantly delayed in rat, but not in monkey basket cells. B : spike threshold was considerably lower in monkey basket cells than that in rat (APs are truncated). C : spikes evoked by rectangular current pulses with the latency of 8 ms still had more negative threshold in monkey ( n = 15) basket cells than that in rat ( n = 14). D : threshold of the 1st spikes and 8-ms-latency spikes is lower in monkeys than that in rats. Error bars represent SE. E : <t>α-dendrotoxin</t> (α-DTX) decreased spike threshold for the 1st spikes evoked in monkey ( n = 4) and rat basket cells ( n = 5).
    α Dendrotoxin, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/α dendrotoxin/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    α dendrotoxin - by Bioz Stars, 2022-05
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    1) Product Images from "Parvalbumin-Positive Basket Interneurons in Monkey and Rat Prefrontal Cortex"

    Article Title: Parvalbumin-Positive Basket Interneurons in Monkey and Rat Prefrontal Cortex

    Journal: Journal of Neurophysiology

    doi: 10.1152/jn.90396.2008

    Properties of the first evoked spike in monkey and rat basket cells. A : first suprathreshold response to the depolarizing current was significantly delayed in rat, but not in monkey basket cells. B : spike threshold was considerably lower in monkey basket cells than that in rat (APs are truncated). C : spikes evoked by rectangular current pulses with the latency of 8 ms still had more negative threshold in monkey ( n = 15) basket cells than that in rat ( n = 14). D : threshold of the 1st spikes and 8-ms-latency spikes is lower in monkeys than that in rats. Error bars represent SE. E : α-dendrotoxin (α-DTX) decreased spike threshold for the 1st spikes evoked in monkey ( n = 4) and rat basket cells ( n = 5).
    Figure Legend Snippet: Properties of the first evoked spike in monkey and rat basket cells. A : first suprathreshold response to the depolarizing current was significantly delayed in rat, but not in monkey basket cells. B : spike threshold was considerably lower in monkey basket cells than that in rat (APs are truncated). C : spikes evoked by rectangular current pulses with the latency of 8 ms still had more negative threshold in monkey ( n = 15) basket cells than that in rat ( n = 14). D : threshold of the 1st spikes and 8-ms-latency spikes is lower in monkeys than that in rats. Error bars represent SE. E : α-dendrotoxin (α-DTX) decreased spike threshold for the 1st spikes evoked in monkey ( n = 4) and rat basket cells ( n = 5).

    Techniques Used: Mass Spectrometry

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    • α dendrotoxin  (Alomone Labs)
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    Alomone Labs α dendrotoxin
    Properties of the first evoked spike in monkey and rat basket cells. A : first suprathreshold response to the depolarizing current was significantly delayed in rat, but not in monkey basket cells. B : spike threshold was considerably lower in monkey basket cells than that in rat (APs are truncated). C : spikes evoked by rectangular current pulses with the latency of 8 ms still had more negative threshold in monkey ( n = 15) basket cells than that in rat ( n = 14). D : threshold of the 1st spikes and 8-ms-latency spikes is lower in monkeys than that in rats. Error bars represent SE. E : <t>α-dendrotoxin</t> (α-DTX) decreased spike threshold for the 1st spikes evoked in monkey ( n = 4) and rat basket cells ( n = 5).
    α Dendrotoxin, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/α dendrotoxin/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    α dendrotoxin - by Bioz Stars, 2022-05
    93/100 stars
    		  Buy from Supplier

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    Properties of the first evoked spike in monkey and rat basket cells. A : first suprathreshold response to the depolarizing current was significantly delayed in rat, but not in monkey basket cells. B : spike threshold was considerably lower in monkey basket cells than that in rat (APs are truncated). C : spikes evoked by rectangular current pulses with the latency of 8 ms still had more negative threshold in monkey ( n = 15) basket cells than that in rat ( n = 14). D : threshold of the 1st spikes and 8-ms-latency spikes is lower in monkeys than that in rats. Error bars represent SE. E : α-dendrotoxin (α-DTX) decreased spike threshold for the 1st spikes evoked in monkey ( n = 4) and rat basket cells ( n = 5).

    Journal: Journal of Neurophysiology

    Article Title: Parvalbumin-Positive Basket Interneurons in Monkey and Rat Prefrontal Cortex

    doi: 10.1152/jn.90396.2008

    Figure Lengend Snippet: Properties of the first evoked spike in monkey and rat basket cells. A : first suprathreshold response to the depolarizing current was significantly delayed in rat, but not in monkey basket cells. B : spike threshold was considerably lower in monkey basket cells than that in rat (APs are truncated). C : spikes evoked by rectangular current pulses with the latency of 8 ms still had more negative threshold in monkey ( n = 15) basket cells than that in rat ( n = 14). D : threshold of the 1st spikes and 8-ms-latency spikes is lower in monkeys than that in rats. Error bars represent SE. E : α-dendrotoxin (α-DTX) decreased spike threshold for the 1st spikes evoked in monkey ( n = 4) and rat basket cells ( n = 5).

    Article Snippet: During some of the experiments, gabazine (4.5–6 μM; Sigma, St. Louis, MO) was added to the bath to block GABAA receptors. d -2-Amino-5-phospho-pentanoic acid (APV, 50 μM; Sigma) and 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX, 20 μM; Sigma) were included in the bath to block N -methyl- d -aspartate (NMDA) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, respectively. α-Dendrotoxin (α-DTX, 150–200 nM; Alomone Labs, Jerusalem, Israel) was used to block Kv1 channels and 4-( N -ethyl- N -phenylamino-1,2-dimethyl-6-methylamino)pyrimidinium chloride (ZD7288, 20 μM; Alomone Labs) was used to block I h channels.

    Techniques: Mass Spectrometry