dnqx  (Alomone Labs)


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    Alomone Labs dnqx

    Dnqx, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 93 stars, based on 1 article reviews
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    dnqx - by Bioz Stars, 2023-01
    93/100 stars

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    1) Product Images from "Distinct regulation of tonic GABAergic inhibition by NMDA receptor subtypes"

    Article Title: Distinct regulation of tonic GABAergic inhibition by NMDA receptor subtypes

    Journal: Cell reports

    doi: 10.1016/j.celrep.2021.109960


    Figure Legend Snippet:

    Techniques Used: Recombinant, Transfection, Mutagenesis, Sequencing, Software

    dnqx  (Alomone Labs)


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    Alomone Labs dnqx

    Dnqx, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 93 stars, based on 1 article reviews
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    dnqx - by Bioz Stars, 2023-01
    93/100 stars

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    1) Product Images from "Distinct regulation of tonic GABAergic inhibition by NMDA receptor subtypes"

    Article Title: Distinct regulation of tonic GABAergic inhibition by NMDA receptor subtypes

    Journal: Cell reports

    doi: 10.1016/j.celrep.2021.109960


    Figure Legend Snippet:

    Techniques Used: Recombinant, Transfection, Mutagenesis, Sequencing, Software

    dnqx  (Alomone Labs)


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    Alomone Labs dnqx

    Dnqx, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/dnqx/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    dnqx - by Bioz Stars, 2023-01
    93/100 stars

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    1) Product Images from "Distinct regulation of tonic GABAergic inhibition by NMDA receptor subtypes"

    Article Title: Distinct regulation of tonic GABAergic inhibition by NMDA receptor subtypes

    Journal: Cell reports

    doi: 10.1016/j.celrep.2021.109960


    Figure Legend Snippet:

    Techniques Used: Recombinant, Transfection, Mutagenesis, Sequencing, Software

    dnqx  (Alomone Labs)


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    Alomone Labs dnqx
    Dnqx, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/dnqx/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
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    dnqx  (Alomone Labs)


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    Alomone Labs dnqx
    Dnqx, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/dnqx/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
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    dnqx  (Alomone Labs)


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    Alomone Labs dnqx
    Dnqx, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/dnqx/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
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    dnqx  (Alomone Labs)


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    KEY RESOURCES TABLE
    Dnqx, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/dnqx/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
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    93/100 stars

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    1) Product Images from "Activity- and sleep-dependent regulation of tonic inhibition by Shisa7"

    Article Title: Activity- and sleep-dependent regulation of tonic inhibition by Shisa7

    Journal: Cell reports

    doi: 10.1016/j.celrep.2021.108899

    KEY RESOURCES TABLE
    Figure Legend Snippet: KEY RESOURCES TABLE

    Techniques Used: Recombinant, Transfection, Protease Inhibitor, Knock-Out, Software

    dnqx  (Alomone Labs)


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    KEY RESOURCES TABLE
    Dnqx, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/dnqx/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
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    dnqx - by Bioz Stars, 2023-01
    93/100 stars

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    1) Product Images from "Activity- and sleep-dependent regulation of tonic inhibition by Shisa7"

    Article Title: Activity- and sleep-dependent regulation of tonic inhibition by Shisa7

    Journal: Cell reports

    doi: 10.1016/j.celrep.2021.108899

    KEY RESOURCES TABLE
    Figure Legend Snippet: KEY RESOURCES TABLE

    Techniques Used: Recombinant, Transfection, Protease Inhibitor, Knock-Out, Software

    dnqx  (Alomone Labs)


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    Alomone Labs dnqx
    Transmitter-specific postsynaptic filtering in SAC→DSGC transmission. (A) Isolation and measurement of spontaneous cholinergic EPSCs in ON-OFF DSGCs. Top , spontaneous EPSCs (sEPSCs) recorded from an ON-OFF DSGC during blockade of AMPA (50 μM <t>DNQX)</t> and NMDA (50 <t>μM</t> <t>D-AP5)</t> receptors. Bottom left , expanded view of boxed region. Dots indicate individual spontaneous EPSCs. Bottom right , alignment and averaging of cholinergic sEPSCs. One hundred individual sEPSCs (light gray) superimposed with the mean (green) of all sEPSCs. Dotted line indicates baseline holding current. (B) Schematic diagram illustrating experimental generation and recording of evoked monophasic IPSCs (emIPSCs) in an ON-OFF DSGC. Brief (<10 ms) optogenetic stimulation of presynaptic SACs evokes a small, monophasic IPSC (red). Following m trials, n monophasic events are distinguished from multiphasic events and failures. (C) Comparison of all sIPSCs and emIPSCs recorded in DSGCs. Amplitude is plotted against decay time constant (τ decay ) for all sIPSCs ( n = 884 events in 4 ON-OFF DSGCs) and emIPSCs ( n = 212 events from 4 ON-OFF DSGCs and 1 ON DSGC). Marginal probability distributions of amplitude and τ decay are shown at right and above, respectively. PSC amplitude—sEPSC vs. emIPSC: *** p < 0.001, D = 0.82 (Kolmogorov-Smirnov test). (D) Averaged time courses of sIPSCs and emIPSCs. The average of all sIPSCs (green) is fit (black, dashed; see Materials and Methods) with a single exponential decay term. The average of all emIPSCs (inverted, magenta) is fit with two exponential decay terms. Traces are normalized to their respective maxima.
    Dnqx, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/dnqx/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    dnqx - by Bioz Stars, 2023-01
    93/100 stars

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    1) Product Images from "Receptoral Mechanisms for Fast Cholinergic Transmission in Direction-Selective Retinal Circuitry"

    Article Title: Receptoral Mechanisms for Fast Cholinergic Transmission in Direction-Selective Retinal Circuitry

    Journal: Frontiers in Cellular Neuroscience

    doi: 10.3389/fncel.2020.604163

    Transmitter-specific postsynaptic filtering in SAC→DSGC transmission. (A) Isolation and measurement of spontaneous cholinergic EPSCs in ON-OFF DSGCs. Top , spontaneous EPSCs (sEPSCs) recorded from an ON-OFF DSGC during blockade of AMPA (50 μM DNQX) and NMDA (50 μM D-AP5) receptors. Bottom left , expanded view of boxed region. Dots indicate individual spontaneous EPSCs. Bottom right , alignment and averaging of cholinergic sEPSCs. One hundred individual sEPSCs (light gray) superimposed with the mean (green) of all sEPSCs. Dotted line indicates baseline holding current. (B) Schematic diagram illustrating experimental generation and recording of evoked monophasic IPSCs (emIPSCs) in an ON-OFF DSGC. Brief (<10 ms) optogenetic stimulation of presynaptic SACs evokes a small, monophasic IPSC (red). Following m trials, n monophasic events are distinguished from multiphasic events and failures. (C) Comparison of all sIPSCs and emIPSCs recorded in DSGCs. Amplitude is plotted against decay time constant (τ decay ) for all sIPSCs ( n = 884 events in 4 ON-OFF DSGCs) and emIPSCs ( n = 212 events from 4 ON-OFF DSGCs and 1 ON DSGC). Marginal probability distributions of amplitude and τ decay are shown at right and above, respectively. PSC amplitude—sEPSC vs. emIPSC: *** p < 0.001, D = 0.82 (Kolmogorov-Smirnov test). (D) Averaged time courses of sIPSCs and emIPSCs. The average of all sIPSCs (green) is fit (black, dashed; see Materials and Methods) with a single exponential decay term. The average of all emIPSCs (inverted, magenta) is fit with two exponential decay terms. Traces are normalized to their respective maxima.
    Figure Legend Snippet: Transmitter-specific postsynaptic filtering in SAC→DSGC transmission. (A) Isolation and measurement of spontaneous cholinergic EPSCs in ON-OFF DSGCs. Top , spontaneous EPSCs (sEPSCs) recorded from an ON-OFF DSGC during blockade of AMPA (50 μM DNQX) and NMDA (50 μM D-AP5) receptors. Bottom left , expanded view of boxed region. Dots indicate individual spontaneous EPSCs. Bottom right , alignment and averaging of cholinergic sEPSCs. One hundred individual sEPSCs (light gray) superimposed with the mean (green) of all sEPSCs. Dotted line indicates baseline holding current. (B) Schematic diagram illustrating experimental generation and recording of evoked monophasic IPSCs (emIPSCs) in an ON-OFF DSGC. Brief (<10 ms) optogenetic stimulation of presynaptic SACs evokes a small, monophasic IPSC (red). Following m trials, n monophasic events are distinguished from multiphasic events and failures. (C) Comparison of all sIPSCs and emIPSCs recorded in DSGCs. Amplitude is plotted against decay time constant (τ decay ) for all sIPSCs ( n = 884 events in 4 ON-OFF DSGCs) and emIPSCs ( n = 212 events from 4 ON-OFF DSGCs and 1 ON DSGC). Marginal probability distributions of amplitude and τ decay are shown at right and above, respectively. PSC amplitude—sEPSC vs. emIPSC: *** p < 0.001, D = 0.82 (Kolmogorov-Smirnov test). (D) Averaged time courses of sIPSCs and emIPSCs. The average of all sIPSCs (green) is fit (black, dashed; see Materials and Methods) with a single exponential decay term. The average of all emIPSCs (inverted, magenta) is fit with two exponential decay terms. Traces are normalized to their respective maxima.

    Techniques Used: Transmission Assay, Isolation

    dnqx  (Alomone Labs)


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    KEY RESOURCES TABLE
    Dnqx, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/dnqx/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
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    93/100 stars

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    1) Product Images from "Molecular dissection of Neuroligin2 and Slitrk3 reveals an essential framework for GABAergic synapse development"

    Article Title: Molecular dissection of Neuroligin2 and Slitrk3 reveals an essential framework for GABAergic synapse development

    Journal: Neuron

    doi: 10.1016/j.neuron.2017.10.003

    KEY RESOURCES TABLE
    Figure Legend Snippet: KEY RESOURCES TABLE

    Techniques Used: Transfection, Protease Inhibitor, Affinity Column, Bicinchoninic Acid Protein Assay, shRNA, Sequencing, Recombinant, Plasmid Preparation, Software

    dnqx  (Alomone Labs)


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    Alomone Labs dnqx
    Dnqx, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/dnqx/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
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    Journal: Cell reports

    Article Title: Distinct regulation of tonic GABAergic inhibition by NMDA receptor subtypes

    doi: 10.1016/j.celrep.2021.109960

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    Article Snippet: Miniature inhibitory postsynaptic currents (mIPSCs) and tonic currents were recorded at −70 mV in the presence of 0.5 μM TTX (Alomone Labs) and 20 μM DNQX (Alomone labs) without exogenous GABA.

    Techniques: Recombinant, Transfection, Mutagenesis, Sequencing, Software