ifo 8155  (ATCC)


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    ATCC ifo 8155
    Ifo 8155, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    wil2 ns crl 8155 cell lines  (ATCC)


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    ATCC wil2 ns crl 8155 cell lines
    Cytotoxic effects of diphenyltin(IV) diisopropyl dithiocarbamate (ODTC 1), diphenyltin(IV) diallyl dithiocarbamate (ODTC 2), triphenyltin(IV) diisopropyl dithiocarbamate (ODTC 3), triphenyltin(IV) diallyl dithiocarbamate (ODTC 4), triphenyltin(IV) diethyl dithiocarbamate (ODTC 5), dimethyltin(IV) diisopropyl dithiocarbamate (ODTC 6) and dimethyltin(IV) diethyl dithiocarbamate (ODTC 7) towards ( a ) Jurkat E6.1 and ( b ) <t>WIL2-NS</t> cell line after 24 h of exposure. The IC 50 values obtained are as shown in the graph above. The data presented are the mean percentage of viable cells (%) ± SEM obtained from three different experiments ( n = 3). * Significant difference ( p < 0.05) from the negative control.
    Wil2 Ns Crl 8155 Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    1) Product Images from "Series of Organotin(IV) Compounds with Different Dithiocarbamate Ligands Induced Cytotoxicity, Apoptosis and Cell Cycle Arrest on Jurkat E6.1, T Acute Lymphoblastic Leukemia Cells"

    Article Title: Series of Organotin(IV) Compounds with Different Dithiocarbamate Ligands Induced Cytotoxicity, Apoptosis and Cell Cycle Arrest on Jurkat E6.1, T Acute Lymphoblastic Leukemia Cells

    Journal: Molecules

    doi: 10.3390/molecules28083376

    Cytotoxic effects of diphenyltin(IV) diisopropyl dithiocarbamate (ODTC 1), diphenyltin(IV) diallyl dithiocarbamate (ODTC 2), triphenyltin(IV) diisopropyl dithiocarbamate (ODTC 3), triphenyltin(IV) diallyl dithiocarbamate (ODTC 4), triphenyltin(IV) diethyl dithiocarbamate (ODTC 5), dimethyltin(IV) diisopropyl dithiocarbamate (ODTC 6) and dimethyltin(IV) diethyl dithiocarbamate (ODTC 7) towards ( a ) Jurkat E6.1 and ( b ) WIL2-NS cell line after 24 h of exposure. The IC 50 values obtained are as shown in the graph above. The data presented are the mean percentage of viable cells (%) ± SEM obtained from three different experiments ( n = 3). * Significant difference ( p < 0.05) from the negative control.
    Figure Legend Snippet: Cytotoxic effects of diphenyltin(IV) diisopropyl dithiocarbamate (ODTC 1), diphenyltin(IV) diallyl dithiocarbamate (ODTC 2), triphenyltin(IV) diisopropyl dithiocarbamate (ODTC 3), triphenyltin(IV) diallyl dithiocarbamate (ODTC 4), triphenyltin(IV) diethyl dithiocarbamate (ODTC 5), dimethyltin(IV) diisopropyl dithiocarbamate (ODTC 6) and dimethyltin(IV) diethyl dithiocarbamate (ODTC 7) towards ( a ) Jurkat E6.1 and ( b ) WIL2-NS cell line after 24 h of exposure. The IC 50 values obtained are as shown in the graph above. The data presented are the mean percentage of viable cells (%) ± SEM obtained from three different experiments ( n = 3). * Significant difference ( p < 0.05) from the negative control.

    Techniques Used: Negative Control

    The IC 50 values of organotin(IV) dithiocarbamate compounds and vincristine against Jurkat E6.1 cells.
    Figure Legend Snippet: The IC 50 values of organotin(IV) dithiocarbamate compounds and vincristine against Jurkat E6.1 cells.

    Techniques Used: Positive Control

    ifo 8155  (ATCC)


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    ATCC ifo 8155
    Ifo 8155, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    crl  (ATCC)


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    ATCC crl
    Crl, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    wil2 ns human b lymphocyte cell line  (ATCC)


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    ATCC wil2 ns human b lymphocyte cell line

    Wil2 Ns Human B Lymphocyte Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    1) Product Images from "Accurate de novo design of membrane-traversing macrocycles"

    Article Title: Accurate de novo design of membrane-traversing macrocycles

    Journal: Cell

    doi: 10.1016/j.cell.2022.07.019


    Figure Legend Snippet:

    Techniques Used: Recombinant, PAMPA Assay, Cell Culture, Modification, Software

    crl 8155 human lymphocytic cells  (ATCC)


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    ATCC crl 8155 human lymphocytic cells
    Crl 8155 Human Lymphocytic Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    wil2 ns  (ATCC)


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    ATCC wil2 ns
    Wil2 Ns, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    wil2 ns cells  (ATCC)


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    ATCC wil2 ns cells
    Wil2 Ns Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    wil2 ns  (ATCC)


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    ATCC wil2 ns
    Culturing procedure for experiments 1–3. Experiment 1: <t>WIL2-NS</t> were cultured in LG or HG with varying concentrations of folic acid for 14 days. Cells were subcultured every 3.5 days and CBMNcyt assay performed on days 7 and 14. Experiment 2: WIL2-NS were cultured under folic acid-deficient or replete conditions for 7 days and subcultured after 3.5 days. MGO or vehicle (HBSS) was added to the media on day 5 for a further 48 h and CBMNcyt assay was performed on day 7. Experiment 3: cells were cultured under folic acid deficient conditions in either LG or HG media for 7 days. Cells were also cultured in the presence or absence of aminoguanidine (100 µmol/l). Cells were subcultured on day 3.5 and CBMNcyt assay was performed on day 7. Ag, aminoguanidine; HG, high glucose (45 mmol/l glucose); LG, low glucose (11.1 mmol/l glucose).
    Wil2 Ns, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    1) Product Images from "Folic acid deficiency increases sensitivity to DNA damage by glucose and methylglyoxal"

    Article Title: Folic acid deficiency increases sensitivity to DNA damage by glucose and methylglyoxal

    Journal: Mutagenesis

    doi: 10.1093/mutage/geac003

    Culturing procedure for experiments 1–3. Experiment 1: WIL2-NS were cultured in LG or HG with varying concentrations of folic acid for 14 days. Cells were subcultured every 3.5 days and CBMNcyt assay performed on days 7 and 14. Experiment 2: WIL2-NS were cultured under folic acid-deficient or replete conditions for 7 days and subcultured after 3.5 days. MGO or vehicle (HBSS) was added to the media on day 5 for a further 48 h and CBMNcyt assay was performed on day 7. Experiment 3: cells were cultured under folic acid deficient conditions in either LG or HG media for 7 days. Cells were also cultured in the presence or absence of aminoguanidine (100 µmol/l). Cells were subcultured on day 3.5 and CBMNcyt assay was performed on day 7. Ag, aminoguanidine; HG, high glucose (45 mmol/l glucose); LG, low glucose (11.1 mmol/l glucose).
    Figure Legend Snippet: Culturing procedure for experiments 1–3. Experiment 1: WIL2-NS were cultured in LG or HG with varying concentrations of folic acid for 14 days. Cells were subcultured every 3.5 days and CBMNcyt assay performed on days 7 and 14. Experiment 2: WIL2-NS were cultured under folic acid-deficient or replete conditions for 7 days and subcultured after 3.5 days. MGO or vehicle (HBSS) was added to the media on day 5 for a further 48 h and CBMNcyt assay was performed on day 7. Experiment 3: cells were cultured under folic acid deficient conditions in either LG or HG media for 7 days. Cells were also cultured in the presence or absence of aminoguanidine (100 µmol/l). Cells were subcultured on day 3.5 and CBMNcyt assay was performed on day 7. Ag, aminoguanidine; HG, high glucose (45 mmol/l glucose); LG, low glucose (11.1 mmol/l glucose).

    Techniques Used: Cell Culture

    Folic acid-deficient WIL2-NS cells are sensitive to glucose-induced DNA damage. (A–D) are DNA damage biomarkers measured at day 7, (E, F) are DNA damage biomarkers measured at day 14. (A, E) MNi/1000 BN. (B, F) NBUDs/1000 BN. (C, G) NPBs/1000 BN. (D, H) Total DNA damage/1000 BN. HG, high glucose; LG, low glucose. Values represent mean ± SD of n = 4. ∗ P < .05, ∗∗∗∗ P < .0001.
    Figure Legend Snippet: Folic acid-deficient WIL2-NS cells are sensitive to glucose-induced DNA damage. (A–D) are DNA damage biomarkers measured at day 7, (E, F) are DNA damage biomarkers measured at day 14. (A, E) MNi/1000 BN. (B, F) NBUDs/1000 BN. (C, G) NPBs/1000 BN. (D, H) Total DNA damage/1000 BN. HG, high glucose; LG, low glucose. Values represent mean ± SD of n = 4. ∗ P < .05, ∗∗∗∗ P < .0001.

    Techniques Used:

    Folic acid-deficient WIL2-NS cells are sensitive to MGO-induced DNA damage. WIL2-NS cells were cultured under low (22.64 nmol/l) or high folic acid (2264 nmol/l) and treated with either HBSS (vehicle) or MGO (100 µmol/l) on day 5. (A) MNi/1000 BN. (B) NBUDs/1000 BN. (C) NPBs/1000 BN. (D) Total DNA damage/1000 BN. Values represent mean ± SD of n = 4. ∗∗∗ P < .001, ∗∗∗∗ P < .0001.
    Figure Legend Snippet: Folic acid-deficient WIL2-NS cells are sensitive to MGO-induced DNA damage. WIL2-NS cells were cultured under low (22.64 nmol/l) or high folic acid (2264 nmol/l) and treated with either HBSS (vehicle) or MGO (100 µmol/l) on day 5. (A) MNi/1000 BN. (B) NBUDs/1000 BN. (C) NPBs/1000 BN. (D) Total DNA damage/1000 BN. Values represent mean ± SD of n = 4. ∗∗∗ P < .001, ∗∗∗∗ P < .0001.

    Techniques Used: Cell Culture

    Aminoguanidine prevents glucose-induced DNA damage in folic acid-deficient cells. WIL2-NS cells were cultured in folic acid-deficient (23 nmol/l) RPMI under low or high glucose with or without aminoguanidine (100 µmol/l. (A) MNi/1000 BN. (B) Medium 8-oxodG (nM). Values represent mean ± SD of n = 4. ∗ P < .05, ∗∗∗ P < .001.
    Figure Legend Snippet: Aminoguanidine prevents glucose-induced DNA damage in folic acid-deficient cells. WIL2-NS cells were cultured in folic acid-deficient (23 nmol/l) RPMI under low or high glucose with or without aminoguanidine (100 µmol/l. (A) MNi/1000 BN. (B) Medium 8-oxodG (nM). Values represent mean ± SD of n = 4. ∗ P < .05, ∗∗∗ P < .001.

    Techniques Used: Cell Culture

    Dicarbonyl stress biomarkers measured in WIL2-NS cells cultured under folic acid-deficient conditions (23 nmol/l) in LG or HG, with or without aminoguanidine.
    Figure Legend Snippet: Dicarbonyl stress biomarkers measured in WIL2-NS cells cultured under folic acid-deficient conditions (23 nmol/l) in LG or HG, with or without aminoguanidine.

    Techniques Used: Cell Culture

    Folic acid deficiency increases concentration of dicarbonyl stress biomarkers. WIL2-NS cells were cultured in folic acid replete (2264 nmol/l) or deficient (23 nmol/l) RPMI under LG for 7 days. (A) Intracellular MGO expressed as relative abundance to control. (B) Medium MGO normalized to cell number (pmol/10 6 cells). (C) Protein-bound concentration of MG-H1 normalized to lysine content (mmol/mol lysine). (D) Protein-bound concentration of CEL normalized to lysine content (mmol/mol lysine). (E) Medium concentration of MG-H1 normalized to cell number (pmol/10 6 cells). (F) Medium concentration of CEL normalized to cell number (pmol/10 6 cells). Values represent mean ± SD of n = 3–4. ∗ P < .05, ∗∗∗∗ P < .0001.
    Figure Legend Snippet: Folic acid deficiency increases concentration of dicarbonyl stress biomarkers. WIL2-NS cells were cultured in folic acid replete (2264 nmol/l) or deficient (23 nmol/l) RPMI under LG for 7 days. (A) Intracellular MGO expressed as relative abundance to control. (B) Medium MGO normalized to cell number (pmol/10 6 cells). (C) Protein-bound concentration of MG-H1 normalized to lysine content (mmol/mol lysine). (D) Protein-bound concentration of CEL normalized to lysine content (mmol/mol lysine). (E) Medium concentration of MG-H1 normalized to cell number (pmol/10 6 cells). (F) Medium concentration of CEL normalized to cell number (pmol/10 6 cells). Values represent mean ± SD of n = 3–4. ∗ P < .05, ∗∗∗∗ P < .0001.

    Techniques Used: Concentration Assay, Cell Culture

    crl  (ATCC)


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    ATCC crl
    Crl, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    human wil2 ns  (ATCC)


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    ATCC human wil2 ns
    Human Wil2 Ns, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    ATCC ifo 8155
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    wil2 ns crl 8155 cell lines  (ATCC)
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    ATCC wil2 ns crl 8155 cell lines
    Cytotoxic effects of diphenyltin(IV) diisopropyl dithiocarbamate (ODTC 1), diphenyltin(IV) diallyl dithiocarbamate (ODTC 2), triphenyltin(IV) diisopropyl dithiocarbamate (ODTC 3), triphenyltin(IV) diallyl dithiocarbamate (ODTC 4), triphenyltin(IV) diethyl dithiocarbamate (ODTC 5), dimethyltin(IV) diisopropyl dithiocarbamate (ODTC 6) and dimethyltin(IV) diethyl dithiocarbamate (ODTC 7) towards ( a ) Jurkat E6.1 and ( b ) <t>WIL2-NS</t> cell line after 24 h of exposure. The IC 50 values obtained are as shown in the graph above. The data presented are the mean percentage of viable cells (%) ± SEM obtained from three different experiments ( n = 3). * Significant difference ( p < 0.05) from the negative control.
    Wil2 Ns Crl 8155 Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    crl  (ATCC)
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    Cytotoxic effects of diphenyltin(IV) diisopropyl dithiocarbamate (ODTC 1), diphenyltin(IV) diallyl dithiocarbamate (ODTC 2), triphenyltin(IV) diisopropyl dithiocarbamate (ODTC 3), triphenyltin(IV) diallyl dithiocarbamate (ODTC 4), triphenyltin(IV) diethyl dithiocarbamate (ODTC 5), dimethyltin(IV) diisopropyl dithiocarbamate (ODTC 6) and dimethyltin(IV) diethyl dithiocarbamate (ODTC 7) towards ( a ) Jurkat E6.1 and ( b ) <t>WIL2-NS</t> cell line after 24 h of exposure. The IC 50 values obtained are as shown in the graph above. The data presented are the mean percentage of viable cells (%) ± SEM obtained from three different experiments ( n = 3). * Significant difference ( p < 0.05) from the negative control.
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    wil2 ns human b lymphocyte cell line  (ATCC)
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    ATCC wil2 ns human b lymphocyte cell line

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    wil2 ns  (ATCC)
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    wil2 ns cells  (ATCC)
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    ATCC wil2 ns cells

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    human wil2 ns  (ATCC)
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    Cytotoxic effects of diphenyltin(IV) diisopropyl dithiocarbamate (ODTC 1), diphenyltin(IV) diallyl dithiocarbamate (ODTC 2), triphenyltin(IV) diisopropyl dithiocarbamate (ODTC 3), triphenyltin(IV) diallyl dithiocarbamate (ODTC 4), triphenyltin(IV) diethyl dithiocarbamate (ODTC 5), dimethyltin(IV) diisopropyl dithiocarbamate (ODTC 6) and dimethyltin(IV) diethyl dithiocarbamate (ODTC 7) towards ( a ) Jurkat E6.1 and ( b ) WIL2-NS cell line after 24 h of exposure. The IC 50 values obtained are as shown in the graph above. The data presented are the mean percentage of viable cells (%) ± SEM obtained from three different experiments ( n = 3). * Significant difference ( p < 0.05) from the negative control.

    Journal: Molecules

    Article Title: Series of Organotin(IV) Compounds with Different Dithiocarbamate Ligands Induced Cytotoxicity, Apoptosis and Cell Cycle Arrest on Jurkat E6.1, T Acute Lymphoblastic Leukemia Cells

    doi: 10.3390/molecules28083376

    Figure Lengend Snippet: Cytotoxic effects of diphenyltin(IV) diisopropyl dithiocarbamate (ODTC 1), diphenyltin(IV) diallyl dithiocarbamate (ODTC 2), triphenyltin(IV) diisopropyl dithiocarbamate (ODTC 3), triphenyltin(IV) diallyl dithiocarbamate (ODTC 4), triphenyltin(IV) diethyl dithiocarbamate (ODTC 5), dimethyltin(IV) diisopropyl dithiocarbamate (ODTC 6) and dimethyltin(IV) diethyl dithiocarbamate (ODTC 7) towards ( a ) Jurkat E6.1 and ( b ) WIL2-NS cell line after 24 h of exposure. The IC 50 values obtained are as shown in the graph above. The data presented are the mean percentage of viable cells (%) ± SEM obtained from three different experiments ( n = 3). * Significant difference ( p < 0.05) from the negative control.

    Article Snippet: The Jurkat E6.1 (TIB-152™) and WIL2-NS (CRL-8155™) cell lines were purchased from the American Type Culture Collection.

    Techniques: Negative Control

    The IC 50 values of organotin(IV) dithiocarbamate compounds and vincristine against Jurkat E6.1 cells.

    Journal: Molecules

    Article Title: Series of Organotin(IV) Compounds with Different Dithiocarbamate Ligands Induced Cytotoxicity, Apoptosis and Cell Cycle Arrest on Jurkat E6.1, T Acute Lymphoblastic Leukemia Cells

    doi: 10.3390/molecules28083376

    Figure Lengend Snippet: The IC 50 values of organotin(IV) dithiocarbamate compounds and vincristine against Jurkat E6.1 cells.

    Article Snippet: The Jurkat E6.1 (TIB-152™) and WIL2-NS (CRL-8155™) cell lines were purchased from the American Type Culture Collection.

    Techniques: Positive Control

    Journal: Cell

    Article Title: Accurate de novo design of membrane-traversing macrocycles

    doi: 10.1016/j.cell.2022.07.019

    Figure Lengend Snippet:

    Article Snippet: WIL2-NS human B lymphocyte cell line , ATCC , CRL-8155.

    Techniques: Recombinant, PAMPA Assay, Cell Culture, Modification, Software