Journal: Molecules
Article Title: Series of Organotin(IV) Compounds with Different Dithiocarbamate Ligands Induced Cytotoxicity, Apoptosis and Cell Cycle Arrest on Jurkat E6.1, T Acute Lymphoblastic Leukemia Cells
doi: 10.3390/molecules28083376
Figure Lengend Snippet: Cytotoxic effects of diphenyltin(IV) diisopropyl dithiocarbamate (ODTC 1), diphenyltin(IV) diallyl dithiocarbamate (ODTC 2), triphenyltin(IV) diisopropyl dithiocarbamate (ODTC 3), triphenyltin(IV) diallyl dithiocarbamate (ODTC 4), triphenyltin(IV) diethyl dithiocarbamate (ODTC 5), dimethyltin(IV) diisopropyl dithiocarbamate (ODTC 6) and dimethyltin(IV) diethyl dithiocarbamate (ODTC 7) towards ( a ) Jurkat E6.1 and ( b ) WIL2-NS cell line after 24 h of exposure. The IC 50 values obtained are as shown in the graph above. The data presented are the mean percentage of viable cells (%) ± SEM obtained from three different experiments ( n = 3). * Significant difference ( p < 0.05) from the negative control.
Article Snippet: The Jurkat E6.1 (TIB-152™) and WIL2-NS (CRL-8155™) cell lines were purchased from the American Type Culture Collection.
Techniques: Negative Control