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normal liver cell line thle 3  (ATCC)


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    ATCC normal liver cell line thle 3
    Normal Liver Cell Line Thle 3, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/normal liver cell line thle 3/product/ATCC
    Average 96 stars, based on 1 article reviews
    normal liver cell line thle 3 - by Bioz Stars, 2025-03
    96/100 stars

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    Expression of typical LCSC markers in normal hepatocytes exposed to various exosomes. (CE: control cellular exosome, UPE: upregulated PRELI cellular exosome, DPE: downregulated PRELI cellular exosome). Fill-patterned bar graphs indicate markers with significant changes. Ns: not significant (* p < 0.05, ** p < 0.01).

    Journal: International Journal of Molecular Sciences

    Article Title: MicroRNA Profiling of PRELI-Modulated Exosomes and Effects on Hepatic Cancer Stem Cells

    doi: 10.3390/ijms252413299

    Figure Lengend Snippet: Expression of typical LCSC markers in normal hepatocytes exposed to various exosomes. (CE: control cellular exosome, UPE: upregulated PRELI cellular exosome, DPE: downregulated PRELI cellular exosome). Fill-patterned bar graphs indicate markers with significant changes. Ns: not significant (* p < 0.05, ** p < 0.01).

    Article Snippet: Liver cancer stem cells (LCSCs) (sku: 36116-43; Celprogen, Torrance, CA, USA) and normal hepatocytes (NHs) (THLE-3; ATCC, Manassas, VA, USA) were cultured with Human Liver Cancer Stem Cell Media (Celprogen) and BEGM (Bronchial Epithelial Cell Growth Medium) (Lonza, Workingham, UK) using BEGM Bullet Kits (Lonza) at 37 °C, 5% CO 2 .

    Techniques: Expressing, Control

    Levels of AKT signaling molecules (phosphorylated AKT and phosphorylated mTORC1) in normal hepatocytes and LCSCs under various exosomes. (CE: control cellular exosome, UPE: upregulated PRELI cellular exosome, DPEs: downregulated PRELI cellular exosome) (* p < 0.05, ** p < 0.01,*** p < 0.001).

    Journal: International Journal of Molecular Sciences

    Article Title: MicroRNA Profiling of PRELI-Modulated Exosomes and Effects on Hepatic Cancer Stem Cells

    doi: 10.3390/ijms252413299

    Figure Lengend Snippet: Levels of AKT signaling molecules (phosphorylated AKT and phosphorylated mTORC1) in normal hepatocytes and LCSCs under various exosomes. (CE: control cellular exosome, UPE: upregulated PRELI cellular exosome, DPEs: downregulated PRELI cellular exosome) (* p < 0.05, ** p < 0.01,*** p < 0.001).

    Article Snippet: Liver cancer stem cells (LCSCs) (sku: 36116-43; Celprogen, Torrance, CA, USA) and normal hepatocytes (NHs) (THLE-3; ATCC, Manassas, VA, USA) were cultured with Human Liver Cancer Stem Cell Media (Celprogen) and BEGM (Bronchial Epithelial Cell Growth Medium) (Lonza, Workingham, UK) using BEGM Bullet Kits (Lonza) at 37 °C, 5% CO 2 .

    Techniques: Control

    Attenuation of drug resistance and cellular viability in SRHs upon inhibition of three miRNAs. ( a ) Results from modeling drug resistance. ( b ) Expression levels of PRELI in SSHs (sorafenib-sensitive hepatocytes) and SRH (sorafenib-resistant hepatocytes). ( c ) Drug resistance in cells transfected with anti-miRNA siRNAs. Fill-patterned bar graphs indicate sensitivity for Sorafenib.CC 50 : cytotoxic concentration 50; NT: non-transfected; T: transfected, Ns: not significant (* p < 0.05, ** p < 0.01).

    Journal: International Journal of Molecular Sciences

    Article Title: MicroRNA Profiling of PRELI-Modulated Exosomes and Effects on Hepatic Cancer Stem Cells

    doi: 10.3390/ijms252413299

    Figure Lengend Snippet: Attenuation of drug resistance and cellular viability in SRHs upon inhibition of three miRNAs. ( a ) Results from modeling drug resistance. ( b ) Expression levels of PRELI in SSHs (sorafenib-sensitive hepatocytes) and SRH (sorafenib-resistant hepatocytes). ( c ) Drug resistance in cells transfected with anti-miRNA siRNAs. Fill-patterned bar graphs indicate sensitivity for Sorafenib.CC 50 : cytotoxic concentration 50; NT: non-transfected; T: transfected, Ns: not significant (* p < 0.05, ** p < 0.01).

    Article Snippet: Liver cancer stem cells (LCSCs) (sku: 36116-43; Celprogen, Torrance, CA, USA) and normal hepatocytes (NHs) (THLE-3; ATCC, Manassas, VA, USA) were cultured with Human Liver Cancer Stem Cell Media (Celprogen) and BEGM (Bronchial Epithelial Cell Growth Medium) (Lonza, Workingham, UK) using BEGM Bullet Kits (Lonza) at 37 °C, 5% CO 2 .

    Techniques: Inhibition, Expressing, Transfection, Concentration Assay