p38 inhibitor sb  (Worthington Biochemical)


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    Structured Review

    Worthington Biochemical p38 inhibitor sb
    PMA (100 nM) and fMLP (100 nM) increased neutrophil O2·− production over 60 min (∗, P < 0.001). Pretreatment of neutrophils with <t>SB-203580</t> (4 μM) 30 min prior to addition of agonist partially decreased PMA-stimulated neutrophil O2·− production (#, P < 0.05) and fully suppressed fMLP-stimulated O2·− production (#, P < 0.001) to levels not different from that of the control.
    P38 Inhibitor Sb, supplied by Worthington Biochemical, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/p38 inhibitor sb/product/Worthington Biochemical
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    p38 inhibitor sb - by Bioz Stars, 2023-03
    86/100 stars

    Images

    1) Product Images from "Pseudomonas aeruginosa Hemolytic Phospholipase C Suppresses Neutrophil Respiratory Burst Activity"

    Article Title: Pseudomonas aeruginosa Hemolytic Phospholipase C Suppresses Neutrophil Respiratory Burst Activity

    Journal:

    doi:

    PMA (100 nM) and fMLP (100 nM) increased neutrophil O2·− production over 60 min (∗, P < 0.001). Pretreatment of neutrophils with SB-203580 (4 μM) 30 min prior to addition of agonist partially decreased PMA-stimulated neutrophil O2·− production (#, P < 0.05) and fully suppressed fMLP-stimulated O2·− production (#, P < 0.001) to levels not different from that of the control.
    Figure Legend Snippet: PMA (100 nM) and fMLP (100 nM) increased neutrophil O2·− production over 60 min (∗, P < 0.001). Pretreatment of neutrophils with SB-203580 (4 μM) 30 min prior to addition of agonist partially decreased PMA-stimulated neutrophil O2·− production (#, P < 0.05) and fully suppressed fMLP-stimulated O2·− production (#, P < 0.001) to levels not different from that of the control.

    Techniques Used:

    Neutrophils exposed to wild-type pseudomonas (PAO1) for 60 min had increased O2·− production compared to unstimulated neutrophils (∗, P < 0.001). The ΔHR mutant stimulated more O2·− production than the wild type (∗∗, P < 0.001). SB-203580 (4 μM, added 30 min prior to exposure to bacteria) partially decreased neutrophil O2·− production stimulated by the ΔHR bacterial strain (#, P < 0.001) and fully suppressed O2·− production in response to the wild-type pseudomonas (##, P < 0.001) to levels not different from that of the control. SB-203580 alone had no effect on O2·− production (P > 0.05).
    Figure Legend Snippet: Neutrophils exposed to wild-type pseudomonas (PAO1) for 60 min had increased O2·− production compared to unstimulated neutrophils (∗, P < 0.001). The ΔHR mutant stimulated more O2·− production than the wild type (∗∗, P < 0.001). SB-203580 (4 μM, added 30 min prior to exposure to bacteria) partially decreased neutrophil O2·− production stimulated by the ΔHR bacterial strain (#, P < 0.001) and fully suppressed O2·− production in response to the wild-type pseudomonas (##, P < 0.001) to levels not different from that of the control. SB-203580 alone had no effect on O2·− production (P > 0.05).

    Techniques Used: Mutagenesis

    p38 inhibitor sb  (Worthington Biochemical)


    Bioz Verified Symbol Worthington Biochemical is a verified supplier
    Bioz Manufacturer Symbol Worthington Biochemical manufactures this product  
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    Structured Review

    Worthington Biochemical p38 inhibitor sb
    PMA (100 nM) and fMLP (100 nM) increased neutrophil O2·− production over 60 min (∗, P < 0.001). Pretreatment of neutrophils with <t>SB-203580</t> (4 μM) 30 min prior to addition of agonist partially decreased PMA-stimulated neutrophil O2·− production (#, P < 0.05) and fully suppressed fMLP-stimulated O2·− production (#, P < 0.001) to levels not different from that of the control.
    P38 Inhibitor Sb, supplied by Worthington Biochemical, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/p38 inhibitor sb/product/Worthington Biochemical
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    p38 inhibitor sb - by Bioz Stars, 2023-03
    86/100 stars

    Images

    1) Product Images from "Pseudomonas aeruginosa Hemolytic Phospholipase C Suppresses Neutrophil Respiratory Burst Activity"

    Article Title: Pseudomonas aeruginosa Hemolytic Phospholipase C Suppresses Neutrophil Respiratory Burst Activity

    Journal:

    doi:

    PMA (100 nM) and fMLP (100 nM) increased neutrophil O2·− production over 60 min (∗, P < 0.001). Pretreatment of neutrophils with SB-203580 (4 μM) 30 min prior to addition of agonist partially decreased PMA-stimulated neutrophil O2·− production (#, P < 0.05) and fully suppressed fMLP-stimulated O2·− production (#, P < 0.001) to levels not different from that of the control.
    Figure Legend Snippet: PMA (100 nM) and fMLP (100 nM) increased neutrophil O2·− production over 60 min (∗, P < 0.001). Pretreatment of neutrophils with SB-203580 (4 μM) 30 min prior to addition of agonist partially decreased PMA-stimulated neutrophil O2·− production (#, P < 0.05) and fully suppressed fMLP-stimulated O2·− production (#, P < 0.001) to levels not different from that of the control.

    Techniques Used:

    Neutrophils exposed to wild-type pseudomonas (PAO1) for 60 min had increased O2·− production compared to unstimulated neutrophils (∗, P < 0.001). The ΔHR mutant stimulated more O2·− production than the wild type (∗∗, P < 0.001). SB-203580 (4 μM, added 30 min prior to exposure to bacteria) partially decreased neutrophil O2·− production stimulated by the ΔHR bacterial strain (#, P < 0.001) and fully suppressed O2·− production in response to the wild-type pseudomonas (##, P < 0.001) to levels not different from that of the control. SB-203580 alone had no effect on O2·− production (P > 0.05).
    Figure Legend Snippet: Neutrophils exposed to wild-type pseudomonas (PAO1) for 60 min had increased O2·− production compared to unstimulated neutrophils (∗, P < 0.001). The ΔHR mutant stimulated more O2·− production than the wild type (∗∗, P < 0.001). SB-203580 (4 μM, added 30 min prior to exposure to bacteria) partially decreased neutrophil O2·− production stimulated by the ΔHR bacterial strain (#, P < 0.001) and fully suppressed O2·− production in response to the wild-type pseudomonas (##, P < 0.001) to levels not different from that of the control. SB-203580 alone had no effect on O2·− production (P > 0.05).

    Techniques Used: Mutagenesis

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    • p38 inhibitor sb  (Worthington Biochemical)
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    Worthington Biochemical p38 inhibitor sb
    PMA (100 nM) and fMLP (100 nM) increased neutrophil O2·− production over 60 min (∗, P < 0.001). Pretreatment of neutrophils with <t>SB-203580</t> (4 μM) 30 min prior to addition of agonist partially decreased PMA-stimulated neutrophil O2·− production (#, P < 0.05) and fully suppressed fMLP-stimulated O2·− production (#, P < 0.001) to levels not different from that of the control.
    P38 Inhibitor Sb, supplied by Worthington Biochemical, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/p38 inhibitor sb/product/Worthington Biochemical
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    p38 inhibitor sb - by Bioz Stars, 2023-03
    86/100 stars
    		  Buy from Supplier

    Image Search Results


    PMA (100 nM) and fMLP (100 nM) increased neutrophil O2·− production over 60 min (∗, P < 0.001). Pretreatment of neutrophils with SB-203580 (4 μM) 30 min prior to addition of agonist partially decreased PMA-stimulated neutrophil O2·− production (#, P < 0.05) and fully suppressed fMLP-stimulated O2·− production (#, P < 0.001) to levels not different from that of the control.

    Journal:

    Article Title: Pseudomonas aeruginosa Hemolytic Phospholipase C Suppresses Neutrophil Respiratory Burst Activity

    doi:

    Figure Lengend Snippet: PMA (100 nM) and fMLP (100 nM) increased neutrophil O2·− production over 60 min (∗, P < 0.001). Pretreatment of neutrophils with SB-203580 (4 μM) 30 min prior to addition of agonist partially decreased PMA-stimulated neutrophil O2·− production (#, P < 0.05) and fully suppressed fMLP-stimulated O2·− production (#, P < 0.001) to levels not different from that of the control.

    Article Snippet: Catalase (81,536 U/mg; bovine liver) was purchased from Worthington Biochemical (Freehold, N.J.), the p38 inhibitor SB-203580 was a gift of SmithKline Beecham (King of Prussia, Pa.), and the protein kinase C (PKC) inhibitor bisindolylmaleimide I was from Calbiochem (San Diego, Calif.).

    Techniques:

    Neutrophils exposed to wild-type pseudomonas (PAO1) for 60 min had increased O2·− production compared to unstimulated neutrophils (∗, P < 0.001). The ΔHR mutant stimulated more O2·− production than the wild type (∗∗, P < 0.001). SB-203580 (4 μM, added 30 min prior to exposure to bacteria) partially decreased neutrophil O2·− production stimulated by the ΔHR bacterial strain (#, P < 0.001) and fully suppressed O2·− production in response to the wild-type pseudomonas (##, P < 0.001) to levels not different from that of the control. SB-203580 alone had no effect on O2·− production (P > 0.05).

    Journal:

    Article Title: Pseudomonas aeruginosa Hemolytic Phospholipase C Suppresses Neutrophil Respiratory Burst Activity

    doi:

    Figure Lengend Snippet: Neutrophils exposed to wild-type pseudomonas (PAO1) for 60 min had increased O2·− production compared to unstimulated neutrophils (∗, P < 0.001). The ΔHR mutant stimulated more O2·− production than the wild type (∗∗, P < 0.001). SB-203580 (4 μM, added 30 min prior to exposure to bacteria) partially decreased neutrophil O2·− production stimulated by the ΔHR bacterial strain (#, P < 0.001) and fully suppressed O2·− production in response to the wild-type pseudomonas (##, P < 0.001) to levels not different from that of the control. SB-203580 alone had no effect on O2·− production (P > 0.05).

    Article Snippet: Catalase (81,536 U/mg; bovine liver) was purchased from Worthington Biochemical (Freehold, N.J.), the p38 inhibitor SB-203580 was a gift of SmithKline Beecham (King of Prussia, Pa.), and the protein kinase C (PKC) inhibitor bisindolylmaleimide I was from Calbiochem (San Diego, Calif.).

    Techniques: Mutagenesis