cyppa  (Alomone Labs)


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    Structured Review

    Alomone Labs cyppa
    SK3–Orai1 interplay in LNCaP cells: Inset table and chemical structures represent the used agonist and antagonist of SK and Orai1 channels. ( A ) Cell viability of LNCaP cells after 24, 48, 72, and 96 h upon the treatment with SK3 channel agonist 10 μM <t>Cyppa,</t> 5 μM NS309, and antagonist 30 μM <t>NS8593,</t> 10 mM 4-AP detected via MTS assay; ( B ) Block diagram represents the cell proliferation of LNCaP cells after 96 h upon conditions described in ( A ). The Mann–Whitney test was used for statistical comparison considering differences statistically significant at p
    Cyppa, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cyppa/product/Alomone Labs
    Average 93 stars, based on 4 article reviews
    Price from $9.99 to $1999.99
    cyppa - by Bioz Stars, 2022-12
    93/100 stars

    Images

    1) Product Images from "Orai1 Boosts SK3 Channel Activation"

    Article Title: Orai1 Boosts SK3 Channel Activation

    Journal: Cancers

    doi: 10.3390/cancers13246357

    SK3–Orai1 interplay in LNCaP cells: Inset table and chemical structures represent the used agonist and antagonist of SK and Orai1 channels. ( A ) Cell viability of LNCaP cells after 24, 48, 72, and 96 h upon the treatment with SK3 channel agonist 10 μM Cyppa, 5 μM NS309, and antagonist 30 μM NS8593, 10 mM 4-AP detected via MTS assay; ( B ) Block diagram represents the cell proliferation of LNCaP cells after 96 h upon conditions described in ( A ). The Mann–Whitney test was used for statistical comparison considering differences statistically significant at p
    Figure Legend Snippet: SK3–Orai1 interplay in LNCaP cells: Inset table and chemical structures represent the used agonist and antagonist of SK and Orai1 channels. ( A ) Cell viability of LNCaP cells after 24, 48, 72, and 96 h upon the treatment with SK3 channel agonist 10 μM Cyppa, 5 μM NS309, and antagonist 30 μM NS8593, 10 mM 4-AP detected via MTS assay; ( B ) Block diagram represents the cell proliferation of LNCaP cells after 96 h upon conditions described in ( A ). The Mann–Whitney test was used for statistical comparison considering differences statistically significant at p

    Techniques Used: MTS Assay, Blocking Assay, MANN-WHITNEY

    2) Product Images from "Ethanol’s Effects on Transient Receptor Potential Channel Expression in Brain Microvascular Endothelial Cells"

    Article Title: Ethanol’s Effects on Transient Receptor Potential Channel Expression in Brain Microvascular Endothelial Cells

    Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology

    doi: 10.1007/s11481-018-9796-3

    Endothelial cell barrier permeability following treatment with a) different concentrations of EtOH or b) the TRPM7 antagonists, NS8593, CyPPA, or SKA-31. * p
    Figure Legend Snippet: Endothelial cell barrier permeability following treatment with a) different concentrations of EtOH or b) the TRPM7 antagonists, NS8593, CyPPA, or SKA-31. * p

    Techniques Used: Permeability

    3) Product Images from "Ethanol’s Effects on Transient Receptor Potential Channel Expression in Brain Microvascular Endothelial Cells"

    Article Title: Ethanol’s Effects on Transient Receptor Potential Channel Expression in Brain Microvascular Endothelial Cells

    Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology

    doi: 10.1007/s11481-018-9796-3

    Endothelial cell barrier permeability following treatment with a) different concentrations of EtOH or b) the TRPM7 antagonists, NS8593, CyPPA, or SKA-31. * p
    Figure Legend Snippet: Endothelial cell barrier permeability following treatment with a) different concentrations of EtOH or b) the TRPM7 antagonists, NS8593, CyPPA, or SKA-31. * p

    Techniques Used: Permeability

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  • 91
    Alomone Labs cyppa
    SK3–Orai1 interplay in LNCaP cells: Inset table and chemical structures represent the used agonist and antagonist of SK and Orai1 channels. ( A ) Cell viability of LNCaP cells after 24, 48, 72, and 96 h upon the treatment with SK3 channel agonist 10 μM <t>Cyppa,</t> 5 μM NS309, and antagonist 30 μM <t>NS8593,</t> 10 mM 4-AP detected via MTS assay; ( B ) Block diagram represents the cell proliferation of LNCaP cells after 96 h upon conditions described in ( A ). The Mann–Whitney test was used for statistical comparison considering differences statistically significant at p
    Cyppa, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cyppa/product/Alomone Labs
    Average 91 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    cyppa - by Bioz Stars, 2022-12
    91/100 stars
      Buy from Supplier

    94
    Alomone Labs anti trpc6 antibody
    SK3–Orai1 interplay in LNCaP cells: Inset table and chemical structures represent the used agonist and antagonist of SK and Orai1 channels. ( A ) Cell viability of LNCaP cells after 24, 48, 72, and 96 h upon the treatment with SK3 channel agonist 10 μM <t>Cyppa,</t> 5 μM NS309, and antagonist 30 μM <t>NS8593,</t> 10 mM 4-AP detected via MTS assay; ( B ) Block diagram represents the cell proliferation of LNCaP cells after 96 h upon conditions described in ( A ). The Mann–Whitney test was used for statistical comparison considering differences statistically significant at p
    Anti Trpc6 Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti trpc6 antibody/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    anti trpc6 antibody - by Bioz Stars, 2022-12
    94/100 stars
      Buy from Supplier

    Image Search Results


    SK3–Orai1 interplay in LNCaP cells: Inset table and chemical structures represent the used agonist and antagonist of SK and Orai1 channels. ( A ) Cell viability of LNCaP cells after 24, 48, 72, and 96 h upon the treatment with SK3 channel agonist 10 μM Cyppa, 5 μM NS309, and antagonist 30 μM NS8593, 10 mM 4-AP detected via MTS assay; ( B ) Block diagram represents the cell proliferation of LNCaP cells after 96 h upon conditions described in ( A ). The Mann–Whitney test was used for statistical comparison considering differences statistically significant at p

    Journal: Cancers

    Article Title: Orai1 Boosts SK3 Channel Activation

    doi: 10.3390/cancers13246357

    Figure Lengend Snippet: SK3–Orai1 interplay in LNCaP cells: Inset table and chemical structures represent the used agonist and antagonist of SK and Orai1 channels. ( A ) Cell viability of LNCaP cells after 24, 48, 72, and 96 h upon the treatment with SK3 channel agonist 10 μM Cyppa, 5 μM NS309, and antagonist 30 μM NS8593, 10 mM 4-AP detected via MTS assay; ( B ) Block diagram represents the cell proliferation of LNCaP cells after 96 h upon conditions described in ( A ). The Mann–Whitney test was used for statistical comparison considering differences statistically significant at p

    Article Snippet: Inhibitors (NS8593 hydrochloride Cat #: N-195, 4-AP Cat #: A-115) and activators (NS-309 Cat #: N-180, 1-EBIO Cat #: E-150, Cyppa Cat #: C-110) were purchased from Alomone Labs (Jerusalem, Israel).

    Techniques: MTS Assay, Blocking Assay, MANN-WHITNEY

    Endothelial cell barrier permeability following treatment with a) different concentrations of EtOH or b) the TRPM7 antagonists, NS8593, CyPPA, or SKA-31. * p

    Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology

    Article Title: Ethanol’s Effects on Transient Receptor Potential Channel Expression in Brain Microvascular Endothelial Cells

    doi: 10.1007/s11481-018-9796-3

    Figure Lengend Snippet: Endothelial cell barrier permeability following treatment with a) different concentrations of EtOH or b) the TRPM7 antagonists, NS8593, CyPPA, or SKA-31. * p

    Article Snippet: For Trpm 7 inhibition, three different Trpm 7 Channel Blockers, NS 8593, CyPPA and SKA-31 (Alomone Labs, Jerusalem, Israel) were added to the inserts at 50 μM, together with a tracer Sodium Fluorescein (NaF) at 10 μg/mL, and incubated in a humidified cell culture incubator at 37 °C with 5% CO2 for 24 h. One hundred microliter samples from both the upper insert and the lower chamber were transferred to a clear 96-well plate.

    Techniques: Permeability