bdnf pro domain (Alomone Labs)


Structured Review

Bdnf Pro Domain, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 7 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bdnf pro domain/product/Alomone Labs
Average 93 stars, based on 7 article reviews
Price from $9.99 to $1999.99
Images
1) Product Images from "Identification of a Linear Epitope in Sortilin That Partakes in Pro-neurotrophin Binding *"
Article Title: Identification of a Linear Epitope in Sortilin That Partakes in Pro-neurotrophin Binding *
Journal: The Journal of Biological Chemistry
doi: 10.1074/jbc.M109.062364

Figure Legend Snippet: Mutational binding analysis of HisS-pro-BDNF to short sortilin fragments. A , HisS-BDNFpro binding analysis to peptides with the wild-type sortilin sequences 163 RIFRSSDF 170 and 170 FAKNFVQTD 178 listed to the left on each membrane. Binding to mutant peptides
Techniques Used: Binding Assay, Mutagenesis
2) Product Images from "Identification of a Linear Epitope in Sortilin That Partakes in Pro-neurotrophin Binding *"
Article Title: Identification of a Linear Epitope in Sortilin That Partakes in Pro-neurotrophin Binding *
Journal: The Journal of Biological Chemistry
doi: 10.1074/jbc.M109.062364

Figure Legend Snippet: Analysis of the NGF and the BDNF pro-domain binding to the mammalian VPS10p receptors by SPOT analysis. A peptide library containing a total of 2181 peptides represented by 734 from sorLA, 403 from sorCS3, 389 from sorCS1, 382 from sorCS2, and 273 from
Techniques Used: Binding Assay

Figure Legend Snippet: Selective competition of ligands by sortilin-derived peptide antagonist. SPR binding analysis of 50 n m unprocessed pro-BDNF ( A ), 50 n m unprocessed pro-NGF ( B ), and 90 n m RAP ( C ) to immobilized sortilin in the absence and presence of the sort166–181
Techniques Used: Derivative Assay, SPR Assay, Binding Assay

Figure Legend Snippet: Mutation of the linear binding site specifically impairs binding of both the NGF and the BDNF pro-domains. SPR analysis showing reduced binding of equal amounts (analyte concentration: 200 n m ) of the soluble extracellular domains of sortilin-4A compared
Techniques Used: Mutagenesis, Binding Assay, SPR Assay, Concentration Assay