p2y1  (Alomone Labs)


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    Structured Review

    Alomone Labs p2y1
    Effectiveness of P2X1 and <t>P2Y1</t> antagonists (A) NF449 (10 −5 M) eliminated α,ß-MetATP induced contractions in proximal (n=6) and (B) distal IPA (n=6). (C) MRS2500 (10 −6 M) did not impair ADP induced relaxation in proximal IPA (n=6) but (D) did decrease relaxation in distal IPA (n=6). (E) MRS2500 did not impair 2-MeSADP induced proximal IPA relaxation (n=8) or (F) reduce distal IPA relaxation to 2-MeSADP (n=8). For all values, mean ± SEM and *p
    P2y1, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/p2y1/product/Alomone Labs
    Average 90 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    p2y1 - by Bioz Stars, 2022-12
    90/100 stars

    Images

    1) Product Images from "Enhanced electrical field stimulated nitrergic and purinergic vasoreactivity in distal versus proximal internal pudendal arteries"

    Article Title: Enhanced electrical field stimulated nitrergic and purinergic vasoreactivity in distal versus proximal internal pudendal arteries

    Journal: The journal of sexual medicine

    doi: 10.1016/j.jsxm.2017.09.013

    Effectiveness of P2X1 and P2Y1 antagonists (A) NF449 (10 −5 M) eliminated α,ß-MetATP induced contractions in proximal (n=6) and (B) distal IPA (n=6). (C) MRS2500 (10 −6 M) did not impair ADP induced relaxation in proximal IPA (n=6) but (D) did decrease relaxation in distal IPA (n=6). (E) MRS2500 did not impair 2-MeSADP induced proximal IPA relaxation (n=8) or (F) reduce distal IPA relaxation to 2-MeSADP (n=8). For all values, mean ± SEM and *p
    Figure Legend Snippet: Effectiveness of P2X1 and P2Y1 antagonists (A) NF449 (10 −5 M) eliminated α,ß-MetATP induced contractions in proximal (n=6) and (B) distal IPA (n=6). (C) MRS2500 (10 −6 M) did not impair ADP induced relaxation in proximal IPA (n=6) but (D) did decrease relaxation in distal IPA (n=6). (E) MRS2500 did not impair 2-MeSADP induced proximal IPA relaxation (n=8) or (F) reduce distal IPA relaxation to 2-MeSADP (n=8). For all values, mean ± SEM and *p

    Techniques Used: Indirect Immunoperoxidase Assay

    No differences in P2X1 and P2Y1 receptor protein expression (A) P2X1 receptor expression in proximal and distal IPA normalized to ß-actin. (B) P2Y1 receptor expression in proximal and distal IPA normalized to ß-actin. For all values, n=8/group and mean ± SEM.
    Figure Legend Snippet: No differences in P2X1 and P2Y1 receptor protein expression (A) P2X1 receptor expression in proximal and distal IPA normalized to ß-actin. (B) P2Y1 receptor expression in proximal and distal IPA normalized to ß-actin. For all values, n=8/group and mean ± SEM.

    Techniques Used: Expressing, Indirect Immunoperoxidase Assay

    Purinergic antagonism improves distal IPA NANC relaxation (A) NANC relaxation with addition of selective P2X1 antagonist, NF449, in proximal and (B) distal IPA (n=8/segment). (C) NANC relaxation with addition of selective P2Y1 antagonist, MRS2500, in proximal and (D) distal IPA (n=8/segment). (E) Combined P2X1 and P2Y1 receptor antagonism in NANC relaxation using NF449 and MRS2500 in proximal and (F) distal IPA (n=8/segment). All values are represented as percent decrease from PE precontraction. For all values, mean ± SEM and *p
    Figure Legend Snippet: Purinergic antagonism improves distal IPA NANC relaxation (A) NANC relaxation with addition of selective P2X1 antagonist, NF449, in proximal and (B) distal IPA (n=8/segment). (C) NANC relaxation with addition of selective P2Y1 antagonist, MRS2500, in proximal and (D) distal IPA (n=8/segment). (E) Combined P2X1 and P2Y1 receptor antagonism in NANC relaxation using NF449 and MRS2500 in proximal and (F) distal IPA (n=8/segment). All values are represented as percent decrease from PE precontraction. For all values, mean ± SEM and *p

    Techniques Used: Indirect Immunoperoxidase Assay

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  • 90
    Alomone Labs p2y1
    Effectiveness of P2X1 and <t>P2Y1</t> antagonists (A) NF449 (10 −5 M) eliminated α,ß-MetATP induced contractions in proximal (n=6) and (B) distal IPA (n=6). (C) MRS2500 (10 −6 M) did not impair ADP induced relaxation in proximal IPA (n=6) but (D) did decrease relaxation in distal IPA (n=6). (E) MRS2500 did not impair 2-MeSADP induced proximal IPA relaxation (n=8) or (F) reduce distal IPA relaxation to 2-MeSADP (n=8). For all values, mean ± SEM and *p
    P2y1, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/p2y1/product/Alomone Labs
    Average 90 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    p2y1 - by Bioz Stars, 2022-12
    90/100 stars
      Buy from Supplier

    Image Search Results


    Effectiveness of P2X1 and P2Y1 antagonists (A) NF449 (10 −5 M) eliminated α,ß-MetATP induced contractions in proximal (n=6) and (B) distal IPA (n=6). (C) MRS2500 (10 −6 M) did not impair ADP induced relaxation in proximal IPA (n=6) but (D) did decrease relaxation in distal IPA (n=6). (E) MRS2500 did not impair 2-MeSADP induced proximal IPA relaxation (n=8) or (F) reduce distal IPA relaxation to 2-MeSADP (n=8). For all values, mean ± SEM and *p

    Journal: The journal of sexual medicine

    Article Title: Enhanced electrical field stimulated nitrergic and purinergic vasoreactivity in distal versus proximal internal pudendal arteries

    doi: 10.1016/j.jsxm.2017.09.013

    Figure Lengend Snippet: Effectiveness of P2X1 and P2Y1 antagonists (A) NF449 (10 −5 M) eliminated α,ß-MetATP induced contractions in proximal (n=6) and (B) distal IPA (n=6). (C) MRS2500 (10 −6 M) did not impair ADP induced relaxation in proximal IPA (n=6) but (D) did decrease relaxation in distal IPA (n=6). (E) MRS2500 did not impair 2-MeSADP induced proximal IPA relaxation (n=8) or (F) reduce distal IPA relaxation to 2-MeSADP (n=8). For all values, mean ± SEM and *p

    Article Snippet: Membranes were incubated with rabbit polyclonal primary antibodies against either P2X1 (1:1,000) or P2Y1 (1:200) receptors (Alomone Labs, Jerusalem, Israel) and conjugated with goat anti-rabbit polyclonal horseradish peroxidase antibody (1:5,000; Thermo Fisher, Waltham, MA, USA).

    Techniques: Indirect Immunoperoxidase Assay

    No differences in P2X1 and P2Y1 receptor protein expression (A) P2X1 receptor expression in proximal and distal IPA normalized to ß-actin. (B) P2Y1 receptor expression in proximal and distal IPA normalized to ß-actin. For all values, n=8/group and mean ± SEM.

    Journal: The journal of sexual medicine

    Article Title: Enhanced electrical field stimulated nitrergic and purinergic vasoreactivity in distal versus proximal internal pudendal arteries

    doi: 10.1016/j.jsxm.2017.09.013

    Figure Lengend Snippet: No differences in P2X1 and P2Y1 receptor protein expression (A) P2X1 receptor expression in proximal and distal IPA normalized to ß-actin. (B) P2Y1 receptor expression in proximal and distal IPA normalized to ß-actin. For all values, n=8/group and mean ± SEM.

    Article Snippet: Membranes were incubated with rabbit polyclonal primary antibodies against either P2X1 (1:1,000) or P2Y1 (1:200) receptors (Alomone Labs, Jerusalem, Israel) and conjugated with goat anti-rabbit polyclonal horseradish peroxidase antibody (1:5,000; Thermo Fisher, Waltham, MA, USA).

    Techniques: Expressing, Indirect Immunoperoxidase Assay

    Purinergic antagonism improves distal IPA NANC relaxation (A) NANC relaxation with addition of selective P2X1 antagonist, NF449, in proximal and (B) distal IPA (n=8/segment). (C) NANC relaxation with addition of selective P2Y1 antagonist, MRS2500, in proximal and (D) distal IPA (n=8/segment). (E) Combined P2X1 and P2Y1 receptor antagonism in NANC relaxation using NF449 and MRS2500 in proximal and (F) distal IPA (n=8/segment). All values are represented as percent decrease from PE precontraction. For all values, mean ± SEM and *p

    Journal: The journal of sexual medicine

    Article Title: Enhanced electrical field stimulated nitrergic and purinergic vasoreactivity in distal versus proximal internal pudendal arteries

    doi: 10.1016/j.jsxm.2017.09.013

    Figure Lengend Snippet: Purinergic antagonism improves distal IPA NANC relaxation (A) NANC relaxation with addition of selective P2X1 antagonist, NF449, in proximal and (B) distal IPA (n=8/segment). (C) NANC relaxation with addition of selective P2Y1 antagonist, MRS2500, in proximal and (D) distal IPA (n=8/segment). (E) Combined P2X1 and P2Y1 receptor antagonism in NANC relaxation using NF449 and MRS2500 in proximal and (F) distal IPA (n=8/segment). All values are represented as percent decrease from PE precontraction. For all values, mean ± SEM and *p

    Article Snippet: Membranes were incubated with rabbit polyclonal primary antibodies against either P2X1 (1:1,000) or P2Y1 (1:200) receptors (Alomone Labs, Jerusalem, Israel) and conjugated with goat anti-rabbit polyclonal horseradish peroxidase antibody (1:5,000; Thermo Fisher, Waltham, MA, USA).

    Techniques: Indirect Immunoperoxidase Assay