p2x4 (Alomone Labs)


Structured Review

P2x4, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/p2x4/product/Alomone Labs
Average 95 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
1) Product Images from "Age-Related Nuclear Translocation of P2X6 Subunit Modifies Splicing Activity Interacting with Splicing Factor 3A1"
Article Title: Age-Related Nuclear Translocation of P2X6 Subunit Modifies Splicing Activity Interacting with Splicing Factor 3A1
Journal: PLoS ONE
doi: 10.1371/journal.pone.0123121

Figure Legend Snippet: Age-dependent expression of P2X6 is not related with senescence. ( a ) Western blot analysis for expression of P2X2, P2X4 and P2X6 proteins in mice (from 1 to 18 month-old) ( b ) Graph represent P2X6, P2X2 and P2X4 levels relative to 1 month-old mice. Levels for P2X6 expression is on average 2.58±0.14-fold higher, P2X4 subunit only increases 1.45±0.19-fold at 8 month, and P2X2 level remains invariable (mean±s.e.m, n = 7 mice, * P
Techniques Used: Expressing, Western Blot, Mouse Assay

Figure Legend Snippet: Expression of P2X6 subunit in adult mice hippocampus. ( a-c ) Immunohistochemical analysis of hippocampus sections from 8 month-old mice. Cells were labeled with antibodies against P2X6 ( a ), P2X4 ( b ) and P2X2 ( c ) subunits. Insets depict enlarged views (40X magnification) of CA3 hippocampal region showing a dotted pattern for P2X6 into the nucleus in addition to cytoplasmic staining ( a ), somatodendritic stainining for P2X4 ( b ) and axonal and cytoplasmic staining for P2X2( c ). Scale bar 200 μm. ( d-f ) Immuno-electron microscopy analysis of a CA3 hippocampal neuron from 8 months-old wild type mouse labeled with anti-P2X6 antibody. The staining is observed both in the cytoplasm (cyt, white arrows) and into the nucleus (nuc, white asterisks). Scale bar 2 μm. ( d-e ) Inset of the area indicated in ( e ) showing a 3.5 X magnification of this indicated area. P2X6 positive regions are mainly located in patches added to the inner nuclear membrane ( e ).
Techniques Used: Expressing, Mouse Assay, Immunohistochemistry, Labeling, Staining, Immuno-Electron Microscopy
2) Product Images from "P2X7R-Panx1 Complex Impairs Bone Mechanosignaling under High Glucose Levels Associated with Type-1 Diabetes"
Article Title: P2X7R-Panx1 Complex Impairs Bone Mechanosignaling under High Glucose Levels Associated with Type-1 Diabetes
Journal: PLoS ONE
doi: 10.1371/journal.pone.0155107

Figure Legend Snippet: Expression of purinergic receptors and pannexin 1 channels is altered in T1D Akita mice bones. (A) Relative protein expression levels of P2R subtypes (P2Y 1 R, P2Y 2 R, P2Y 4 R, P2X3R, P2X4R and P2X7R) and Panx1 in 8-week-old Akita and age-matched wildtype bone tissue (Data are presented as the means ± SEM *P
Techniques Used: Expressing, Mouse Assay
3) Product Images from "Distinct Localization of P2X Receptors at Excitatory Postsynaptic Specializations"
Article Title: Distinct Localization of P2X Receptors at Excitatory Postsynaptic Specializations
Journal: The Journal of Neuroscience
doi: 10.1523/JNEUROSCI.21-02-00641.2001

Figure Legend Snippet: Immunogold labeling for P2X2 , P2X4 , and P2X6 at synapses of parallel fibers onto Purkinje cells in cerebellum
Techniques Used: Labeling

Figure Legend Snippet: Immunogold labeling for P2X2 , P2X4 , and P2X6 at synapses of Schaffer collaterals onto CA1 pyramidal cells in hippocampus
Techniques Used: Labeling