girk2  (Alomone Labs)


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    Structured Review

    Alomone Labs girk2
    <t>GIRK2</t> is not regulated by Gα i3 in whole oocytes
    Girk2, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 85/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/girk2/product/Alomone Labs
    Average 85 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    girk2 - by Bioz Stars, 2022-11
    85/100 stars

    Images

    1) Product Images from "Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K+ channel by G?iGDP and G??"

    Article Title: Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K+ channel by G?iGDP and G??

    Journal:

    doi: 10.1113/jphysiol.2009.173229

    GIRK2 is not regulated by Gα i3 in whole oocytes
    Figure Legend Snippet: GIRK2 is not regulated by Gα i3 in whole oocytes

    Techniques Used:

    Functional differences between homomeric GIRK1 and GIRK2
    Figure Legend Snippet: Functional differences between homomeric GIRK1 and GIRK2

    Techniques Used: Functional Assay

    Gα i3 GA does not regulate GIRK2 in excised plasma membrane patches
    Figure Legend Snippet: Gα i3 GA does not regulate GIRK2 in excised plasma membrane patches

    Techniques Used:

    Biochemical and functional differences between GIRK1 and GIRK2
    Figure Legend Snippet: Biochemical and functional differences between GIRK1 and GIRK2

    Techniques Used: Functional Assay

    The basal activity is Gβγ dependent in GIRK1*, but Gβγ independent in GIRK2
    Figure Legend Snippet: The basal activity is Gβγ dependent in GIRK1*, but Gβγ independent in GIRK2

    Techniques Used: Activity Assay

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  • 85
    Alomone Labs girk2
    <t>GIRK2</t> is not regulated by Gα i3 in whole oocytes
    Girk2, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 85/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/girk2/product/Alomone Labs
    Average 85 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    girk2 - by Bioz Stars, 2022-11
    85/100 stars
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    GIRK2 is not regulated by Gα i3 in whole oocytes

    Journal:

    Article Title: Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K+ channel by G?iGDP and G??

    doi: 10.1113/jphysiol.2009.173229

    Figure Lengend Snippet: GIRK2 is not regulated by Gα i3 in whole oocytes

    Article Snippet: It is highly unlikely that the high I basal of GIRK1* (or GIRK1/2) depends on ‘free’ Gβγ elevated by some ‘constitutively active’ GPCR present in the oocyte, because GIRK2 (which is highly sensitive to both Gβγ and ACh) shows almost no Gβγ-dependent I basal .

    Techniques:

    Functional differences between homomeric GIRK1 and GIRK2

    Journal:

    Article Title: Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K+ channel by G?iGDP and G??

    doi: 10.1113/jphysiol.2009.173229

    Figure Lengend Snippet: Functional differences between homomeric GIRK1 and GIRK2

    Article Snippet: It is highly unlikely that the high I basal of GIRK1* (or GIRK1/2) depends on ‘free’ Gβγ elevated by some ‘constitutively active’ GPCR present in the oocyte, because GIRK2 (which is highly sensitive to both Gβγ and ACh) shows almost no Gβγ-dependent I basal .

    Techniques: Functional Assay

    Gα i3 GA does not regulate GIRK2 in excised plasma membrane patches

    Journal:

    Article Title: Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K+ channel by G?iGDP and G??

    doi: 10.1113/jphysiol.2009.173229

    Figure Lengend Snippet: Gα i3 GA does not regulate GIRK2 in excised plasma membrane patches

    Article Snippet: It is highly unlikely that the high I basal of GIRK1* (or GIRK1/2) depends on ‘free’ Gβγ elevated by some ‘constitutively active’ GPCR present in the oocyte, because GIRK2 (which is highly sensitive to both Gβγ and ACh) shows almost no Gβγ-dependent I basal .

    Techniques:

    Biochemical and functional differences between GIRK1 and GIRK2

    Journal:

    Article Title: Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K+ channel by G?iGDP and G??

    doi: 10.1113/jphysiol.2009.173229

    Figure Lengend Snippet: Biochemical and functional differences between GIRK1 and GIRK2

    Article Snippet: It is highly unlikely that the high I basal of GIRK1* (or GIRK1/2) depends on ‘free’ Gβγ elevated by some ‘constitutively active’ GPCR present in the oocyte, because GIRK2 (which is highly sensitive to both Gβγ and ACh) shows almost no Gβγ-dependent I basal .

    Techniques: Functional Assay

    The basal activity is Gβγ dependent in GIRK1*, but Gβγ independent in GIRK2

    Journal:

    Article Title: Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K+ channel by G?iGDP and G??

    doi: 10.1113/jphysiol.2009.173229

    Figure Lengend Snippet: The basal activity is Gβγ dependent in GIRK1*, but Gβγ independent in GIRK2

    Article Snippet: It is highly unlikely that the high I basal of GIRK1* (or GIRK1/2) depends on ‘free’ Gβγ elevated by some ‘constitutively active’ GPCR present in the oocyte, because GIRK2 (which is highly sensitive to both Gβγ and ACh) shows almost no Gβγ-dependent I basal .

    Techniques: Activity Assay