anti neurotensin receptor 1 extracellular antibody  (Alomone Labs)


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    Alomone Labs anti neurotensin receptor 1 extracellular antibody
    NTSR2, but not <t>NTSR1,</t> is overexpressed in B-CLL. ( a ) Quantitative analyses of NTSR1 and NTSR2 mRNA levels in normal B ( n =15) and B-CLL ( n =30) lymphocytes, normalized against HPRT . Data are expressed as mean fold change in expression (±s.e.m.) vs normal B cells. ( b ) Quantitative analyses of NTSR2 mRNA level in indolent (Indol.) vs progressive (prog.) patients, wild-type ( wt ) vs mutant ( Mut. ) IGHV , wild-type ( wt ) vs mutant (deleted, del. ) p53, CD38 negative (neg.) vs positive (pos.), and absence (no) vs presence of 13q14 deletion (del.); values are given in arbitrary units (a.u.). ( c ) Representative analysis of NTSR2 expression from B-lymphocyte lysates from two normal donors (D1, D2) and two B-CLL patients (P1, P2). ( d ) NTSR2 expression, normalized against actin, in normal B ( n =6) and B-CLL ( n =6) lymphocytes (means±s.e.m. of three independent experiments). Significant P -values are indicated in the graphs *** P
    Anti Neurotensin Receptor 1 Extracellular Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti neurotensin receptor 1 extracellular antibody/product/Alomone Labs
    Average 90 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    anti neurotensin receptor 1 extracellular antibody - by Bioz Stars, 2022-08
    90/100 stars

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    1) Product Images from "Neurotensin receptor type 2 protects B-cell chronic lymphocytic leukemia cells from apoptosis"

    Article Title: Neurotensin receptor type 2 protects B-cell chronic lymphocytic leukemia cells from apoptosis

    Journal: Oncogene

    doi: 10.1038/onc.2017.365

    NTSR2, but not NTSR1, is overexpressed in B-CLL. ( a ) Quantitative analyses of NTSR1 and NTSR2 mRNA levels in normal B ( n =15) and B-CLL ( n =30) lymphocytes, normalized against HPRT . Data are expressed as mean fold change in expression (±s.e.m.) vs normal B cells. ( b ) Quantitative analyses of NTSR2 mRNA level in indolent (Indol.) vs progressive (prog.) patients, wild-type ( wt ) vs mutant ( Mut. ) IGHV , wild-type ( wt ) vs mutant (deleted, del. ) p53, CD38 negative (neg.) vs positive (pos.), and absence (no) vs presence of 13q14 deletion (del.); values are given in arbitrary units (a.u.). ( c ) Representative analysis of NTSR2 expression from B-lymphocyte lysates from two normal donors (D1, D2) and two B-CLL patients (P1, P2). ( d ) NTSR2 expression, normalized against actin, in normal B ( n =6) and B-CLL ( n =6) lymphocytes (means±s.e.m. of three independent experiments). Significant P -values are indicated in the graphs *** P
    Figure Legend Snippet: NTSR2, but not NTSR1, is overexpressed in B-CLL. ( a ) Quantitative analyses of NTSR1 and NTSR2 mRNA levels in normal B ( n =15) and B-CLL ( n =30) lymphocytes, normalized against HPRT . Data are expressed as mean fold change in expression (±s.e.m.) vs normal B cells. ( b ) Quantitative analyses of NTSR2 mRNA level in indolent (Indol.) vs progressive (prog.) patients, wild-type ( wt ) vs mutant ( Mut. ) IGHV , wild-type ( wt ) vs mutant (deleted, del. ) p53, CD38 negative (neg.) vs positive (pos.), and absence (no) vs presence of 13q14 deletion (del.); values are given in arbitrary units (a.u.). ( c ) Representative analysis of NTSR2 expression from B-lymphocyte lysates from two normal donors (D1, D2) and two B-CLL patients (P1, P2). ( d ) NTSR2 expression, normalized against actin, in normal B ( n =6) and B-CLL ( n =6) lymphocytes (means±s.e.m. of three independent experiments). Significant P -values are indicated in the graphs *** P

    Techniques Used: Expressing, Mutagenesis

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    Alomone Labs anti neurotensin receptor 1 extracellular antibody
    NTSR2, but not <t>NTSR1,</t> is overexpressed in B-CLL. ( a ) Quantitative analyses of NTSR1 and NTSR2 mRNA levels in normal B ( n =15) and B-CLL ( n =30) lymphocytes, normalized against HPRT . Data are expressed as mean fold change in expression (±s.e.m.) vs normal B cells. ( b ) Quantitative analyses of NTSR2 mRNA level in indolent (Indol.) vs progressive (prog.) patients, wild-type ( wt ) vs mutant ( Mut. ) IGHV , wild-type ( wt ) vs mutant (deleted, del. ) p53, CD38 negative (neg.) vs positive (pos.), and absence (no) vs presence of 13q14 deletion (del.); values are given in arbitrary units (a.u.). ( c ) Representative analysis of NTSR2 expression from B-lymphocyte lysates from two normal donors (D1, D2) and two B-CLL patients (P1, P2). ( d ) NTSR2 expression, normalized against actin, in normal B ( n =6) and B-CLL ( n =6) lymphocytes (means±s.e.m. of three independent experiments). Significant P -values are indicated in the graphs *** P
    Anti Neurotensin Receptor 1 Extracellular Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti neurotensin receptor 1 extracellular antibody/product/Alomone Labs
    Average 90 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    anti neurotensin receptor 1 extracellular antibody - by Bioz Stars, 2022-08
    90/100 stars
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    NTSR2, but not NTSR1, is overexpressed in B-CLL. ( a ) Quantitative analyses of NTSR1 and NTSR2 mRNA levels in normal B ( n =15) and B-CLL ( n =30) lymphocytes, normalized against HPRT . Data are expressed as mean fold change in expression (±s.e.m.) vs normal B cells. ( b ) Quantitative analyses of NTSR2 mRNA level in indolent (Indol.) vs progressive (prog.) patients, wild-type ( wt ) vs mutant ( Mut. ) IGHV , wild-type ( wt ) vs mutant (deleted, del. ) p53, CD38 negative (neg.) vs positive (pos.), and absence (no) vs presence of 13q14 deletion (del.); values are given in arbitrary units (a.u.). ( c ) Representative analysis of NTSR2 expression from B-lymphocyte lysates from two normal donors (D1, D2) and two B-CLL patients (P1, P2). ( d ) NTSR2 expression, normalized against actin, in normal B ( n =6) and B-CLL ( n =6) lymphocytes (means±s.e.m. of three independent experiments). Significant P -values are indicated in the graphs *** P

    Journal: Oncogene

    Article Title: Neurotensin receptor type 2 protects B-cell chronic lymphocytic leukemia cells from apoptosis

    doi: 10.1038/onc.2017.365

    Figure Lengend Snippet: NTSR2, but not NTSR1, is overexpressed in B-CLL. ( a ) Quantitative analyses of NTSR1 and NTSR2 mRNA levels in normal B ( n =15) and B-CLL ( n =30) lymphocytes, normalized against HPRT . Data are expressed as mean fold change in expression (±s.e.m.) vs normal B cells. ( b ) Quantitative analyses of NTSR2 mRNA level in indolent (Indol.) vs progressive (prog.) patients, wild-type ( wt ) vs mutant ( Mut. ) IGHV , wild-type ( wt ) vs mutant (deleted, del. ) p53, CD38 negative (neg.) vs positive (pos.), and absence (no) vs presence of 13q14 deletion (del.); values are given in arbitrary units (a.u.). ( c ) Representative analysis of NTSR2 expression from B-lymphocyte lysates from two normal donors (D1, D2) and two B-CLL patients (P1, P2). ( d ) NTSR2 expression, normalized against actin, in normal B ( n =6) and B-CLL ( n =6) lymphocytes (means±s.e.m. of three independent experiments). Significant P -values are indicated in the graphs *** P

    Article Snippet: Proteins obtained as described previously were blotted onto polyvinylidene fluoride membrane (Calbiochem/Merck Millipore) and incubated with following antibodies: rabbit anti-NTSR-1 (ANT-015), rabbit anti-NTSR-2 (ANT-016), Alomone Labs; rabbit anti-Bcl-2 (sc-783, Santa Cruz Biotechnology, Dallas, TX, USA); rabbit anti-Bcl-xL (#2764S), rabbit anti-phospho-Akt (Ser473) (#4060S), mouse anti-Akt (pan; #2920S), rabbit anti-phospho-Src family (Tyr416; #6943S), rabbit anti-Src (#2108S), rabbit anti-phospho-p38 MAPK (Thr180/Tyr182; #9211S), rabbit anti-p38 MAPK (#8690S), rabbit anti-phospho-SAPK/JNK (Thr183/Tyr185; #4668S), and rabbit anti-SAPK/JNK (#9252), all from Cell Signaling Technology (Danvers, MA, USA); mouse anti-Giα1/2 antibody (06-236, Calbiochem/Merck Millipore); and anti-actin (A5441, Sigma-Aldrich).

    Techniques: Expressing, Mutagenesis