anti neuropilin 1 nrp1 extracellular antibody  (Alomone Labs)


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    Structured Review

    Alomone Labs anti neuropilin 1 nrp1 extracellular antibody
    AnkB440 stabilizes the Sema 3A receptor complex <t>L1CAM-Nrp1</t> at the cell surface of GCs. ( A ) Western blot analysis of the expression of Sema 3A, L1CAM and the Sema 3A receptors Nrp1 and Plexin A1 in the cortex of PND1 control and AnkB440 KO mice. ( B ) Quantification of protein levels normalized to actin in cortical lysates from PND1 mice of indicated genotypes relative to their levels in control brains. Data show mean ± SEM for three biological replicates per genotype. Unpaired t test. *p
    Anti Neuropilin 1 Nrp1 Extracellular Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti neuropilin 1 nrp1 extracellular antibody/product/Alomone Labs
    Average 93 stars, based on 2 article reviews
    Price from $9.99 to $1999.99
    anti neuropilin 1 nrp1 extracellular antibody - by Bioz Stars, 2022-08
    93/100 stars

    Images

    1) Product Images from "Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor Sema 3A"

    Article Title: Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor Sema 3A

    Journal: bioRxiv

    doi: 10.1101/2021.05.03.442401

    AnkB440 stabilizes the Sema 3A receptor complex L1CAM-Nrp1 at the cell surface of GCs. ( A ) Western blot analysis of the expression of Sema 3A, L1CAM and the Sema 3A receptors Nrp1 and Plexin A1 in the cortex of PND1 control and AnkB440 KO mice. ( B ) Quantification of protein levels normalized to actin in cortical lysates from PND1 mice of indicated genotypes relative to their levels in control brains. Data show mean ± SEM for three biological replicates per genotype. Unpaired t test. *p
    Figure Legend Snippet: AnkB440 stabilizes the Sema 3A receptor complex L1CAM-Nrp1 at the cell surface of GCs. ( A ) Western blot analysis of the expression of Sema 3A, L1CAM and the Sema 3A receptors Nrp1 and Plexin A1 in the cortex of PND1 control and AnkB440 KO mice. ( B ) Quantification of protein levels normalized to actin in cortical lysates from PND1 mice of indicated genotypes relative to their levels in control brains. Data show mean ± SEM for three biological replicates per genotype. Unpaired t test. *p

    Techniques Used: Western Blot, Expressing, Mouse Assay

    2) Product Images from "Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A"

    Article Title: Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A

    Journal: eLife

    doi: 10.7554/eLife.69815

    Proposed mechanism of AnkB440-mediated growth cone collapse. AnkB440 binds the cytoplasmic domain of L1CAM to stabilize the L1CAM-Nrp1 holoreceptor complex at the cell surface. Transduction of Sema 3 A signals via the AnkB440-L1CAM-Nrp1 complex modulates F-actin dynamics through LIMK phosphorylation of cofilin to facilitate local F-actin disassembly and the collapse of GCs from the axon and collateral branches independently of βII-spectrin, or of AnkB440 interaction with microtubules. Source data . Source data contain the original files of the full raw unedited gels or blots and figures with the uncropped gels or blots with the relevant bands clearly labelled. Source data files also include numerical data that are represented as graphs in the figures.
    Figure Legend Snippet: Proposed mechanism of AnkB440-mediated growth cone collapse. AnkB440 binds the cytoplasmic domain of L1CAM to stabilize the L1CAM-Nrp1 holoreceptor complex at the cell surface. Transduction of Sema 3 A signals via the AnkB440-L1CAM-Nrp1 complex modulates F-actin dynamics through LIMK phosphorylation of cofilin to facilitate local F-actin disassembly and the collapse of GCs from the axon and collateral branches independently of βII-spectrin, or of AnkB440 interaction with microtubules. Source data . Source data contain the original files of the full raw unedited gels or blots and figures with the uncropped gels or blots with the relevant bands clearly labelled. Source data files also include numerical data that are represented as graphs in the figures.

    Techniques Used: Transduction

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    • anti neuropilin 1 nrp1 extracellular antibody  (Alomone Labs)
    93
    Alomone Labs anti neuropilin 1 nrp1 extracellular antibody
    AnkB440 stabilizes the Sema 3A receptor complex <t>L1CAM-Nrp1</t> at the cell surface of GCs. ( A ) Western blot analysis of the expression of Sema 3A, L1CAM and the Sema 3A receptors Nrp1 and Plexin A1 in the cortex of PND1 control and AnkB440 KO mice. ( B ) Quantification of protein levels normalized to actin in cortical lysates from PND1 mice of indicated genotypes relative to their levels in control brains. Data show mean ± SEM for three biological replicates per genotype. Unpaired t test. *p
    Anti Neuropilin 1 Nrp1 Extracellular Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti neuropilin 1 nrp1 extracellular antibody/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    anti neuropilin 1 nrp1 extracellular antibody - by Bioz Stars, 2022-08
    93/100 stars
    		  Buy from Supplier

    Image Search Results


    AnkB440 stabilizes the Sema 3A receptor complex L1CAM-Nrp1 at the cell surface of GCs. ( A ) Western blot analysis of the expression of Sema 3A, L1CAM and the Sema 3A receptors Nrp1 and Plexin A1 in the cortex of PND1 control and AnkB440 KO mice. ( B ) Quantification of protein levels normalized to actin in cortical lysates from PND1 mice of indicated genotypes relative to their levels in control brains. Data show mean ± SEM for three biological replicates per genotype. Unpaired t test. *p

    Journal: bioRxiv

    Article Title: Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor Sema 3A

    doi: 10.1101/2021.05.03.442401

    Figure Lengend Snippet: AnkB440 stabilizes the Sema 3A receptor complex L1CAM-Nrp1 at the cell surface of GCs. ( A ) Western blot analysis of the expression of Sema 3A, L1CAM and the Sema 3A receptors Nrp1 and Plexin A1 in the cortex of PND1 control and AnkB440 KO mice. ( B ) Quantification of protein levels normalized to actin in cortical lysates from PND1 mice of indicated genotypes relative to their levels in control brains. Data show mean ± SEM for three biological replicates per genotype. Unpaired t test. *p

    Article Snippet: Detection of surface Nrp1 by immunofluorescence was conducted using rabbit anti-Nrp1 extracellular antibody (1:50, # ANR-063, Alomone) that recognizes amino acid residues 502-514 in the extracellular N-terminus of Nrp1.

    Techniques: Western Blot, Expressing, Mouse Assay

    Proposed mechanism of AnkB440-mediated growth cone collapse. AnkB440 binds the cytoplasmic domain of L1CAM to stabilize the L1CAM-Nrp1 holoreceptor complex at the cell surface. Transduction of Sema 3 A signals via the AnkB440-L1CAM-Nrp1 complex modulates F-actin dynamics through LIMK phosphorylation of cofilin to facilitate local F-actin disassembly and the collapse of GCs from the axon and collateral branches independently of βII-spectrin, or of AnkB440 interaction with microtubules. Source data . Source data contain the original files of the full raw unedited gels or blots and figures with the uncropped gels or blots with the relevant bands clearly labelled. Source data files also include numerical data that are represented as graphs in the figures.

    Journal: eLife

    Article Title: Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A

    doi: 10.7554/eLife.69815

    Figure Lengend Snippet: Proposed mechanism of AnkB440-mediated growth cone collapse. AnkB440 binds the cytoplasmic domain of L1CAM to stabilize the L1CAM-Nrp1 holoreceptor complex at the cell surface. Transduction of Sema 3 A signals via the AnkB440-L1CAM-Nrp1 complex modulates F-actin dynamics through LIMK phosphorylation of cofilin to facilitate local F-actin disassembly and the collapse of GCs from the axon and collateral branches independently of βII-spectrin, or of AnkB440 interaction with microtubules. Source data . Source data contain the original files of the full raw unedited gels or blots and figures with the uncropped gels or blots with the relevant bands clearly labelled. Source data files also include numerical data that are represented as graphs in the figures.

    Article Snippet: Detection of surface Nrp1 by immunofluorescence was conducted using rabbit anti-Nrp1 extracellular antibody (1:50, # ANR-063, Alomone) that recognizes amino acid residues 502–514 in the extracellular N-terminus of Nrp1.

    Techniques: Transduction