chrm2 (Alomone Labs)


Structured Review

Chrm2, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/chrm2/product/Alomone Labs
Average 93 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
1) Product Images from "Inducible Deletion of YAP and TAZ in Adult Mouse Smooth Muscle Causes Rapid and Lethal Colonic Pseudo-Obstruction"
Article Title: Inducible Deletion of YAP and TAZ in Adult Mouse Smooth Muscle Causes Rapid and Lethal Colonic Pseudo-Obstruction
Journal: Cellular and Molecular Gastroenterology and Hepatology
doi: 10.1016/j.jcmgh.2020.09.014

Figure Legend Snippet: Correlation between YAP/TAZ, MRTF/SRF, and muscarinic receptors in the human GI tract and urinary bladder . ( A ) For the table, RNA sequencing data from GTExPortal.org was used to correlate mRNA levels of YAP1 , TEAD3 , and WWTR1 vs MYOCD , MRTFA , SRF , CHRM2 , and CHRM3 . Spearman Rho values for the indicated correlations are given for 5 sections of the GI tract and the urinary bladder. All Spearman Rho values in bold have a P value less than .0001. Examples of correlations in the transverse colon are highlighted in gray. ( B ) Examples of correlations in the transverse colon are plotted. White lines are best-fit linear regression lines. eso GEJ, esophagus gastroesophageal junction; colon s., colon sigmoid; colon t., colon transverse; ter. ileum, terminal ileum; TPM, transcripts per million.
Techniques Used: RNA Sequencing Assay
2) Product Images from "Induction of detrusor underactivity by extensive vascular endothelial damages of iliac arteries in a rat model and its pathophysiology in the genetic levels"
Article Title: Induction of detrusor underactivity by extensive vascular endothelial damages of iliac arteries in a rat model and its pathophysiology in the genetic levels
Journal: Scientific Reports
doi: 10.1038/s41598-019-52811-4

Figure Legend Snippet: Repression of P2rx1 by progressive vascular endothelial damage. ( a – c ) RQ-PCR ( a ) and western blot ( b , c ) analysis of the expressions of the cholinergic receptor muscarinic 2 ( Chrm2 ), cholinergic receptor muscarinic 3 ( Chrm3 ), and purinergic receptor P2X 1 ( P2rx1 ) genes in the bladders of rats in the indicated groups. Expression levels of the indicated transcripts are presented as % Gapdh . For western blot analysis, β-actin was used as a loading control, and the expression levels of the indicated proteins were normalized to the β-actin value. ( d , e ) Representative images ( d ) and quantification analysis ( e ) of the immunohistochemical staining for the P2rx1 protein (original magnification ×200, scale bar = 200 μm). All quantification results are presented as mean ± SEM. *p
Techniques Used: Polymerase Chain Reaction, Western Blot, Expressing, Immunohistochemistry, Staining