Anti Mglur1, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 94 stars, based on 1 article reviews
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1) Product Images from "Disassembly of Shank and Homer Synaptic Clusters Is Driven by Soluble ?-Amyloid1-40 through Divergent NMDAR-Dependent Signalling Pathways"
Article Title: Disassembly of Shank and Homer Synaptic Clusters Is Driven by Soluble ?-Amyloid1-40 through Divergent NMDAR-Dependent Signalling Pathways
Journal: PLoS ONE
Figure Legend Snippet: Dispersal of synaptic mGluR1 clusters by Aβ requires NMDAR and VDCC activity. Rat cortical neurons were treated with Aβ (1 µM) for 1 h (with or without co-treatment with the NMDAR antagonist MK801, or the VDCC blocker verapamil) and then immunostained for surface mGluR1 before fixation. (A, B) Aβ downregulates surface mGluR1 (surface cluster size 66.0±2.8%, N = 10, n = 300, p
Techniques Used: Activity Assay
2) Product Images from "Metabotropic glutamate receptors (mGluR5) activate TRPC channels to improve the regularity of the respiratory rhythm generated by the pre-B?tzinger Complex in mice"
Article Title: Metabotropic glutamate receptors (mGluR5) activate TRPC channels to improve the regularity of the respiratory rhythm generated by the pre-B?tzinger Complex in mice
Journal: The European Journal of Neuroscience
Figure Legend Snippet: Blocking mGluR5 with MPEP increases inspiratory neuron burst irregularity and decreases neuron burst frequency while additionally blocking mGluR1 with LY367385 does not further alter these parameters
Techniques Used: Blocking Assay
3) Product Images from "Metabotropic glutamate receptor-1 regulates inflammation in triple negative breast cancer"
Article Title: Metabotropic glutamate receptor-1 regulates inflammation in triple negative breast cancer
Journal: Scientific Reports
Figure Legend Snippet: GRM1 and mGluR1 expression in TNBC. ( A ) Knockdown of GRM1 was accomplished by infecting MDA-MB-231 cells with GIPZ shRNA Lentiviral vectors containing a puromycin resistance gene and shRNA against GRM1 or a non-silencing shRNA construct (NS). GRM1 overexpression was accomplished by infecting MDA-MB-468 cells with pLenti6.3/V5-TOPO vectors containing a blasticidin resistance gene and GRM1 or LACZ construct ( LACZ ). Cells were stably selected with puromycin (1 μg/ml) or blasticidin (5 μg/ml) for 7 days and levels of GRM1 message ( A ) or its corresponding protein, mGluR1 ( B ) were measured by QPCR or Western blot, respectively. mGluR1 expression in SUM159, BT549 and non-transduced MDA-MB-231 TNBC cell lines were also detected. Results in A represent n = 2 experiments and are expressed as the mean ± SEM where *is P
Techniques Used: Expressing, Multiple Displacement Amplification, shRNA, Construct, Over Expression, Stable Transfection, Real-time Polymerase Chain Reaction, Western Blot