arcaine sulfate  (Alomone Labs)


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    Structured Review

    Alomone Labs arcaine sulfate
    LBD mutations do not affect spermine binding site. ( a ) Representative traces from oocytes co-expressing hGluN1a and hGluN2B- wt (blue) or GluN2B-G689C (cyan) or G689S (red) in response to block by <t>arcaine</t> (200 μM), after receptors have been activated by saturating glycine (100 μM) and glutamate (5 mM) at pH 6.5. Then, application of incrementing concentrations of spermine (concentration indicated next to plot; in μM) are added in the presence of arcaine, showing increases of the current despite antagonist. Arrowhead indicates I basal at pH 6.5, prior block by arcaine. ( b ) Summary of arcaine-dependent antagonism of the current. ( c ) Summary of spermine potentiation at pH=6.5 in the presence of 200 μM arcaine. ( d ) Summary of I basal at pH=6.5, showing that 2B wt receptors exhibit smallest I basal . *, p
    Arcaine Sulfate, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/arcaine sulfate/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    arcaine sulfate - by Bioz Stars, 2022-12
    93/100 stars

    Images

    1) Product Images from "Two de novo GluN2B mutations affect multiple NMDAR-functions and instigate severe pediatric encephalopathy"

    Article Title: Two de novo GluN2B mutations affect multiple NMDAR-functions and instigate severe pediatric encephalopathy

    Journal: eLife

    doi: 10.7554/eLife.67555

    LBD mutations do not affect spermine binding site. ( a ) Representative traces from oocytes co-expressing hGluN1a and hGluN2B- wt (blue) or GluN2B-G689C (cyan) or G689S (red) in response to block by arcaine (200 μM), after receptors have been activated by saturating glycine (100 μM) and glutamate (5 mM) at pH 6.5. Then, application of incrementing concentrations of spermine (concentration indicated next to plot; in μM) are added in the presence of arcaine, showing increases of the current despite antagonist. Arrowhead indicates I basal at pH 6.5, prior block by arcaine. ( b ) Summary of arcaine-dependent antagonism of the current. ( c ) Summary of spermine potentiation at pH=6.5 in the presence of 200 μM arcaine. ( d ) Summary of I basal at pH=6.5, showing that 2B wt receptors exhibit smallest I basal . *, p
    Figure Legend Snippet: LBD mutations do not affect spermine binding site. ( a ) Representative traces from oocytes co-expressing hGluN1a and hGluN2B- wt (blue) or GluN2B-G689C (cyan) or G689S (red) in response to block by arcaine (200 μM), after receptors have been activated by saturating glycine (100 μM) and glutamate (5 mM) at pH 6.5. Then, application of incrementing concentrations of spermine (concentration indicated next to plot; in μM) are added in the presence of arcaine, showing increases of the current despite antagonist. Arrowhead indicates I basal at pH 6.5, prior block by arcaine. ( b ) Summary of arcaine-dependent antagonism of the current. ( c ) Summary of spermine potentiation at pH=6.5 in the presence of 200 μM arcaine. ( d ) Summary of I basal at pH=6.5, showing that 2B wt receptors exhibit smallest I basal . *, p

    Techniques Used: Binding Assay, Expressing, Blocking Assay, Concentration Assay

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    • arcaine sulfate  (Alomone Labs)
    93
    Alomone Labs arcaine sulfate
    LBD mutations do not affect spermine binding site. ( a ) Representative traces from oocytes co-expressing hGluN1a and hGluN2B- wt (blue) or GluN2B-G689C (cyan) or G689S (red) in response to block by <t>arcaine</t> (200 μM), after receptors have been activated by saturating glycine (100 μM) and glutamate (5 mM) at pH 6.5. Then, application of incrementing concentrations of spermine (concentration indicated next to plot; in μM) are added in the presence of arcaine, showing increases of the current despite antagonist. Arrowhead indicates I basal at pH 6.5, prior block by arcaine. ( b ) Summary of arcaine-dependent antagonism of the current. ( c ) Summary of spermine potentiation at pH=6.5 in the presence of 200 μM arcaine. ( d ) Summary of I basal at pH=6.5, showing that 2B wt receptors exhibit smallest I basal . *, p
    Arcaine Sulfate, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/arcaine sulfate/product/Alomone Labs
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    arcaine sulfate - by Bioz Stars, 2022-12
    93/100 stars
    		  Buy from Supplier
    cleavage resistant human mutant prongf  (Alomone Labs)
    91
    Alomone Labs cleavage resistant human mutant prongf
    LBD mutations do not affect spermine binding site. ( a ) Representative traces from oocytes co-expressing hGluN1a and hGluN2B- wt (blue) or GluN2B-G689C (cyan) or G689S (red) in response to block by <t>arcaine</t> (200 μM), after receptors have been activated by saturating glycine (100 μM) and glutamate (5 mM) at pH 6.5. Then, application of incrementing concentrations of spermine (concentration indicated next to plot; in μM) are added in the presence of arcaine, showing increases of the current despite antagonist. Arrowhead indicates I basal at pH 6.5, prior block by arcaine. ( b ) Summary of arcaine-dependent antagonism of the current. ( c ) Summary of spermine potentiation at pH=6.5 in the presence of 200 μM arcaine. ( d ) Summary of I basal at pH=6.5, showing that 2B wt receptors exhibit smallest I basal . *, p
    Cleavage Resistant Human Mutant Prongf, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cleavage resistant human mutant prongf/product/Alomone Labs
    Average 91 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    cleavage resistant human mutant prongf - by Bioz Stars, 2022-12
    91/100 stars
    		  Buy from Supplier

    Image Search Results


    LBD mutations do not affect spermine binding site. ( a ) Representative traces from oocytes co-expressing hGluN1a and hGluN2B- wt (blue) or GluN2B-G689C (cyan) or G689S (red) in response to block by arcaine (200 μM), after receptors have been activated by saturating glycine (100 μM) and glutamate (5 mM) at pH 6.5. Then, application of incrementing concentrations of spermine (concentration indicated next to plot; in μM) are added in the presence of arcaine, showing increases of the current despite antagonist. Arrowhead indicates I basal at pH 6.5, prior block by arcaine. ( b ) Summary of arcaine-dependent antagonism of the current. ( c ) Summary of spermine potentiation at pH=6.5 in the presence of 200 μM arcaine. ( d ) Summary of I basal at pH=6.5, showing that 2B wt receptors exhibit smallest I basal . *, p

    Journal: eLife

    Article Title: Two de novo GluN2B mutations affect multiple NMDAR-functions and instigate severe pediatric encephalopathy

    doi: 10.7554/eLife.67555

    Figure Lengend Snippet: LBD mutations do not affect spermine binding site. ( a ) Representative traces from oocytes co-expressing hGluN1a and hGluN2B- wt (blue) or GluN2B-G689C (cyan) or G689S (red) in response to block by arcaine (200 μM), after receptors have been activated by saturating glycine (100 μM) and glutamate (5 mM) at pH 6.5. Then, application of incrementing concentrations of spermine (concentration indicated next to plot; in μM) are added in the presence of arcaine, showing increases of the current despite antagonist. Arrowhead indicates I basal at pH 6.5, prior block by arcaine. ( b ) Summary of arcaine-dependent antagonism of the current. ( c ) Summary of spermine potentiation at pH=6.5 in the presence of 200 μM arcaine. ( d ) Summary of I basal at pH=6.5, showing that 2B wt receptors exhibit smallest I basal . *, p

    Article Snippet: Arcaine sulfate was purchased from Alomone labs (Cat. # 14923-17-2).

    Techniques: Binding Assay, Expressing, Blocking Assay, Concentration Assay