m z 8766 9  (ATCC)


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    ATCC m z 8766 9
    The peaks of ribosomal protein L27, L28, L29, L30, and hemophore-related protein are indicated in red for M. abscessus subsp. abscessus (ATCC 19977 T ), green for M. abscessus subsp. bolletii (JCM 15297 T ), and blue for M. abscessus subsp. massiliense (JCM 15300 T ). ( a ) The peaks of m/z 8766.9, m/z 8780.9, and m/z 8780.9 are represented as ribosomal protein L29 of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively. ( b ) The peaks m/z 6765.9, and m/z 6795.9 are represented as ribosomal protein L30 of M. abscessus subsp. bolletii (JCM 15297 T ) (green), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. massiliense (JCM 15300 T ) (blue), respectively. ( c ) The peaks m/z 9500.3, m/z 9473.8, and m/z 9473.8 are represented as hemophore-related protein of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively.
    M Z 8766 9, supplied by ATCC, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    m z 8766 9 - by Bioz Stars, 2024-07
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    1) Product Images from "Identification of Mycobacterium abscessus using the peaks of ribosomal protein L29, L30 and hemophore-related protein by MALDI-MS proteotyping"

    Article Title: Identification of Mycobacterium abscessus using the peaks of ribosomal protein L29, L30 and hemophore-related protein by MALDI-MS proteotyping

    Journal: Scientific Reports

    doi: 10.1038/s41598-024-61549-7

    The peaks of ribosomal protein L27, L28, L29, L30, and hemophore-related protein are indicated in red for M. abscessus subsp. abscessus (ATCC 19977 T ), green for M. abscessus subsp. bolletii (JCM 15297 T ), and blue for M. abscessus subsp. massiliense (JCM 15300 T ). ( a ) The peaks of m/z 8766.9, m/z 8780.9, and m/z 8780.9 are represented as ribosomal protein L29 of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively. ( b ) The peaks m/z 6765.9, and m/z 6795.9 are represented as ribosomal protein L30 of M. abscessus subsp. bolletii (JCM 15297 T ) (green), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. massiliense (JCM 15300 T ) (blue), respectively. ( c ) The peaks m/z 9500.3, m/z 9473.8, and m/z 9473.8 are represented as hemophore-related protein of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively.
    Figure Legend Snippet: The peaks of ribosomal protein L27, L28, L29, L30, and hemophore-related protein are indicated in red for M. abscessus subsp. abscessus (ATCC 19977 T ), green for M. abscessus subsp. bolletii (JCM 15297 T ), and blue for M. abscessus subsp. massiliense (JCM 15300 T ). ( a ) The peaks of m/z 8766.9, m/z 8780.9, and m/z 8780.9 are represented as ribosomal protein L29 of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively. ( b ) The peaks m/z 6765.9, and m/z 6795.9 are represented as ribosomal protein L30 of M. abscessus subsp. bolletii (JCM 15297 T ) (green), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. massiliense (JCM 15300 T ) (blue), respectively. ( c ) The peaks m/z 9500.3, m/z 9473.8, and m/z 9473.8 are represented as hemophore-related protein of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively.

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    m z 8766 9  (ATCC)


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    ATCC m z 8766 9
    M Z 8766 9, supplied by ATCC, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    VECTOR-BEST a 8766
    A 8766, supplied by VECTOR-BEST, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Cambridge Isotope Laboratories ulm 8766 pk d4 lysine cambridge isotope
    Ulm 8766 Pk D4 Lysine Cambridge Isotope, supplied by Cambridge Isotope Laboratories, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    russia elisa kit cat no a 8756 a 8766 and a 8768  (VECTOR-BEST)

     
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    VECTOR-BEST russia elisa kit cat no a 8756 a 8766 and a 8768
    Russia Elisa Kit Cat No A 8756 A 8766 And A 8768, supplied by VECTOR-BEST, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    p ikkε ser172  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc p ikkε ser172
    P Ikkε Ser172, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    at5g47220 erf2 unigene 8766 1 24 0 89 at2g37630 myb91 unigene  (Unigene)

     
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    Unigene at5g47220 erf2 unigene 8766 1 24 0 89 at2g37630 myb91 unigene
    At5g47220 Erf2 Unigene 8766 1 24 0 89 At2g37630 Myb91 Unigene, supplied by Unigene, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    p tbk1  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc p tbk1
    In vivo validation of the mechanism of NAP inhibiting colon cancer. A The KEGG enrichment analysis indicated that the immune-related pathway was regulated after TMPs treatment. B GSEA algorithm was used to analyze the changes in the cytosolic DNA-sensing pathway after TMPs treatment. C <t>p-TBK1(Ser172)</t> and p-IRF3(Ser386), markers of activation of innate immune pathway cytosolic DNA-sensing, were detected after TMPs treatment. D – F RT-qPCR detected downstream target genes of the DNA-sensing pathway. G – H Representative flow analysis of CD3 + CD4 + T cells and CD3 + CD8 + T cells in tumor tissues. I – J Representative fluorescent images of CD3 + CD4 + T cells and CD3 + CD8 + T cells in tumor tissues. (n = 6, scale bars:100 μm)
    P Tbk1, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    1) Product Images from "Apoptotic tumor cell-derived microparticles loading Napabucasin inhibit CSCs and synergistic immune therapy"

    Article Title: Apoptotic tumor cell-derived microparticles loading Napabucasin inhibit CSCs and synergistic immune therapy

    Journal: Journal of Nanobiotechnology

    doi: 10.1186/s12951-023-01792-8

    In vivo validation of the mechanism of NAP inhibiting colon cancer. A The KEGG enrichment analysis indicated that the immune-related pathway was regulated after TMPs treatment. B GSEA algorithm was used to analyze the changes in the cytosolic DNA-sensing pathway after TMPs treatment. C p-TBK1(Ser172) and p-IRF3(Ser386), markers of activation of innate immune pathway cytosolic DNA-sensing, were detected after TMPs treatment. D – F RT-qPCR detected downstream target genes of the DNA-sensing pathway. G – H Representative flow analysis of CD3 + CD4 + T cells and CD3 + CD8 + T cells in tumor tissues. I – J Representative fluorescent images of CD3 + CD4 + T cells and CD3 + CD8 + T cells in tumor tissues. (n = 6, scale bars:100 μm)
    Figure Legend Snippet: In vivo validation of the mechanism of NAP inhibiting colon cancer. A The KEGG enrichment analysis indicated that the immune-related pathway was regulated after TMPs treatment. B GSEA algorithm was used to analyze the changes in the cytosolic DNA-sensing pathway after TMPs treatment. C p-TBK1(Ser172) and p-IRF3(Ser386), markers of activation of innate immune pathway cytosolic DNA-sensing, were detected after TMPs treatment. D – F RT-qPCR detected downstream target genes of the DNA-sensing pathway. G – H Representative flow analysis of CD3 + CD4 + T cells and CD3 + CD8 + T cells in tumor tissues. I – J Representative fluorescent images of CD3 + CD4 + T cells and CD3 + CD8 + T cells in tumor tissues. (n = 6, scale bars:100 μm)

    Techniques Used: In Vivo, Activation Assay, Quantitative RT-PCR

    human phospho ikke  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc human phospho ikke
    Human Phospho Ikke, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    p ikk ser172  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc p ikk ser172
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    ATCC m z 8766 9
    The peaks of ribosomal protein L27, L28, L29, L30, and hemophore-related protein are indicated in red for M. abscessus subsp. abscessus (ATCC 19977 T ), green for M. abscessus subsp. bolletii (JCM 15297 T ), and blue for M. abscessus subsp. massiliense (JCM 15300 T ). ( a ) The peaks of m/z 8766.9, m/z 8780.9, and m/z 8780.9 are represented as ribosomal protein L29 of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively. ( b ) The peaks m/z 6765.9, and m/z 6795.9 are represented as ribosomal protein L30 of M. abscessus subsp. bolletii (JCM 15297 T ) (green), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. massiliense (JCM 15300 T ) (blue), respectively. ( c ) The peaks m/z 9500.3, m/z 9473.8, and m/z 9473.8 are represented as hemophore-related protein of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively.
    M Z 8766 9, supplied by ATCC, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    VECTOR-BEST a 8766
    The peaks of ribosomal protein L27, L28, L29, L30, and hemophore-related protein are indicated in red for M. abscessus subsp. abscessus (ATCC 19977 T ), green for M. abscessus subsp. bolletii (JCM 15297 T ), and blue for M. abscessus subsp. massiliense (JCM 15300 T ). ( a ) The peaks of m/z 8766.9, m/z 8780.9, and m/z 8780.9 are represented as ribosomal protein L29 of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively. ( b ) The peaks m/z 6765.9, and m/z 6795.9 are represented as ribosomal protein L30 of M. abscessus subsp. bolletii (JCM 15297 T ) (green), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. massiliense (JCM 15300 T ) (blue), respectively. ( c ) The peaks m/z 9500.3, m/z 9473.8, and m/z 9473.8 are represented as hemophore-related protein of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively.
    A 8766, supplied by VECTOR-BEST, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Cambridge Isotope Laboratories ulm 8766 pk d4 lysine cambridge isotope
    The peaks of ribosomal protein L27, L28, L29, L30, and hemophore-related protein are indicated in red for M. abscessus subsp. abscessus (ATCC 19977 T ), green for M. abscessus subsp. bolletii (JCM 15297 T ), and blue for M. abscessus subsp. massiliense (JCM 15300 T ). ( a ) The peaks of m/z 8766.9, m/z 8780.9, and m/z 8780.9 are represented as ribosomal protein L29 of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively. ( b ) The peaks m/z 6765.9, and m/z 6795.9 are represented as ribosomal protein L30 of M. abscessus subsp. bolletii (JCM 15297 T ) (green), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. massiliense (JCM 15300 T ) (blue), respectively. ( c ) The peaks m/z 9500.3, m/z 9473.8, and m/z 9473.8 are represented as hemophore-related protein of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively.
    Ulm 8766 Pk D4 Lysine Cambridge Isotope, supplied by Cambridge Isotope Laboratories, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    VECTOR-BEST russia elisa kit cat no a 8756 a 8766 and a 8768
    The peaks of ribosomal protein L27, L28, L29, L30, and hemophore-related protein are indicated in red for M. abscessus subsp. abscessus (ATCC 19977 T ), green for M. abscessus subsp. bolletii (JCM 15297 T ), and blue for M. abscessus subsp. massiliense (JCM 15300 T ). ( a ) The peaks of m/z 8766.9, m/z 8780.9, and m/z 8780.9 are represented as ribosomal protein L29 of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively. ( b ) The peaks m/z 6765.9, and m/z 6795.9 are represented as ribosomal protein L30 of M. abscessus subsp. bolletii (JCM 15297 T ) (green), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. massiliense (JCM 15300 T ) (blue), respectively. ( c ) The peaks m/z 9500.3, m/z 9473.8, and m/z 9473.8 are represented as hemophore-related protein of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively.
    Russia Elisa Kit Cat No A 8756 A 8766 And A 8768, supplied by VECTOR-BEST, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Cell Signaling Technology Inc p ikkε ser172
    The peaks of ribosomal protein L27, L28, L29, L30, and hemophore-related protein are indicated in red for M. abscessus subsp. abscessus (ATCC 19977 T ), green for M. abscessus subsp. bolletii (JCM 15297 T ), and blue for M. abscessus subsp. massiliense (JCM 15300 T ). ( a ) The peaks of m/z 8766.9, m/z 8780.9, and m/z 8780.9 are represented as ribosomal protein L29 of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively. ( b ) The peaks m/z 6765.9, and m/z 6795.9 are represented as ribosomal protein L30 of M. abscessus subsp. bolletii (JCM 15297 T ) (green), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. massiliense (JCM 15300 T ) (blue), respectively. ( c ) The peaks m/z 9500.3, m/z 9473.8, and m/z 9473.8 are represented as hemophore-related protein of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively.
    P Ikkε Ser172, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Unigene at5g47220 erf2 unigene 8766 1 24 0 89 at2g37630 myb91 unigene
    The peaks of ribosomal protein L27, L28, L29, L30, and hemophore-related protein are indicated in red for M. abscessus subsp. abscessus (ATCC 19977 T ), green for M. abscessus subsp. bolletii (JCM 15297 T ), and blue for M. abscessus subsp. massiliense (JCM 15300 T ). ( a ) The peaks of m/z 8766.9, m/z 8780.9, and m/z 8780.9 are represented as ribosomal protein L29 of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively. ( b ) The peaks m/z 6765.9, and m/z 6795.9 are represented as ribosomal protein L30 of M. abscessus subsp. bolletii (JCM 15297 T ) (green), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. massiliense (JCM 15300 T ) (blue), respectively. ( c ) The peaks m/z 9500.3, m/z 9473.8, and m/z 9473.8 are represented as hemophore-related protein of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively.
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    In vivo validation of the mechanism of NAP inhibiting colon cancer. A The KEGG enrichment analysis indicated that the immune-related pathway was regulated after TMPs treatment. B GSEA algorithm was used to analyze the changes in the cytosolic DNA-sensing pathway after TMPs treatment. C <t>p-TBK1(Ser172)</t> and p-IRF3(Ser386), markers of activation of innate immune pathway cytosolic DNA-sensing, were detected after TMPs treatment. D – F RT-qPCR detected downstream target genes of the DNA-sensing pathway. G – H Representative flow analysis of CD3 + CD4 + T cells and CD3 + CD8 + T cells in tumor tissues. I – J Representative fluorescent images of CD3 + CD4 + T cells and CD3 + CD8 + T cells in tumor tissues. (n = 6, scale bars:100 μm)
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    In vivo validation of the mechanism of NAP inhibiting colon cancer. A The KEGG enrichment analysis indicated that the immune-related pathway was regulated after TMPs treatment. B GSEA algorithm was used to analyze the changes in the cytosolic DNA-sensing pathway after TMPs treatment. C <t>p-TBK1(Ser172)</t> and p-IRF3(Ser386), markers of activation of innate immune pathway cytosolic DNA-sensing, were detected after TMPs treatment. D – F RT-qPCR detected downstream target genes of the DNA-sensing pathway. G – H Representative flow analysis of CD3 + CD4 + T cells and CD3 + CD8 + T cells in tumor tissues. I – J Representative fluorescent images of CD3 + CD4 + T cells and CD3 + CD8 + T cells in tumor tissues. (n = 6, scale bars:100 μm)
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    Image Search Results


    The peaks of ribosomal protein L27, L28, L29, L30, and hemophore-related protein are indicated in red for M. abscessus subsp. abscessus (ATCC 19977 T ), green for M. abscessus subsp. bolletii (JCM 15297 T ), and blue for M. abscessus subsp. massiliense (JCM 15300 T ). ( a ) The peaks of m/z 8766.9, m/z 8780.9, and m/z 8780.9 are represented as ribosomal protein L29 of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively. ( b ) The peaks m/z 6765.9, and m/z 6795.9 are represented as ribosomal protein L30 of M. abscessus subsp. bolletii (JCM 15297 T ) (green), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. massiliense (JCM 15300 T ) (blue), respectively. ( c ) The peaks m/z 9500.3, m/z 9473.8, and m/z 9473.8 are represented as hemophore-related protein of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively.

    Journal: Scientific Reports

    Article Title: Identification of Mycobacterium abscessus using the peaks of ribosomal protein L29, L30 and hemophore-related protein by MALDI-MS proteotyping

    doi: 10.1038/s41598-024-61549-7

    Figure Lengend Snippet: The peaks of ribosomal protein L27, L28, L29, L30, and hemophore-related protein are indicated in red for M. abscessus subsp. abscessus (ATCC 19977 T ), green for M. abscessus subsp. bolletii (JCM 15297 T ), and blue for M. abscessus subsp. massiliense (JCM 15300 T ). ( a ) The peaks of m/z 8766.9, m/z 8780.9, and m/z 8780.9 are represented as ribosomal protein L29 of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively. ( b ) The peaks m/z 6765.9, and m/z 6795.9 are represented as ribosomal protein L30 of M. abscessus subsp. bolletii (JCM 15297 T ) (green), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. massiliense (JCM 15300 T ) (blue), respectively. ( c ) The peaks m/z 9500.3, m/z 9473.8, and m/z 9473.8 are represented as hemophore-related protein of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively.

    Article Snippet: Figure 2 The peaks of ribosomal protein L27, L28, L29, L30, and hemophore-related protein are indicated in red for M. abscessus subsp. abscessus (ATCC 19977 T ), green for M. abscessus subsp. bolletii (JCM 15297 T ), and blue for M. abscessus subsp. massiliense (JCM 15300 T ). ( a ) The peaks of m/z 8766.9, m/z 8780.9, and m/z 8780.9 are represented as ribosomal protein L29 of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively. ( b ) The peaks m/z 6765.9, and m/z 6795.9 are represented as ribosomal protein L30 of M. abscessus subsp. bolletii (JCM 15297 T ) (green), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. massiliense (JCM 15300 T ) (blue), respectively. ( c ) The peaks m/z 9500.3, m/z 9473.8, and m/z 9473.8 are represented as hemophore-related protein of M. abscessus subsp. massiliense (JCM 15300 T ) (blue), M. abscessus subsp. abscessus (ATCC 19977 T ) (red), and M. abscessus subsp. bolletii (JCM 15297 T ) (green), respectively.

    Techniques:

    In vivo validation of the mechanism of NAP inhibiting colon cancer. A The KEGG enrichment analysis indicated that the immune-related pathway was regulated after TMPs treatment. B GSEA algorithm was used to analyze the changes in the cytosolic DNA-sensing pathway after TMPs treatment. C p-TBK1(Ser172) and p-IRF3(Ser386), markers of activation of innate immune pathway cytosolic DNA-sensing, were detected after TMPs treatment. D – F RT-qPCR detected downstream target genes of the DNA-sensing pathway. G – H Representative flow analysis of CD3 + CD4 + T cells and CD3 + CD8 + T cells in tumor tissues. I – J Representative fluorescent images of CD3 + CD4 + T cells and CD3 + CD8 + T cells in tumor tissues. (n = 6, scale bars:100 μm)

    Journal: Journal of Nanobiotechnology

    Article Title: Apoptotic tumor cell-derived microparticles loading Napabucasin inhibit CSCs and synergistic immune therapy

    doi: 10.1186/s12951-023-01792-8

    Figure Lengend Snippet: In vivo validation of the mechanism of NAP inhibiting colon cancer. A The KEGG enrichment analysis indicated that the immune-related pathway was regulated after TMPs treatment. B GSEA algorithm was used to analyze the changes in the cytosolic DNA-sensing pathway after TMPs treatment. C p-TBK1(Ser172) and p-IRF3(Ser386), markers of activation of innate immune pathway cytosolic DNA-sensing, were detected after TMPs treatment. D – F RT-qPCR detected downstream target genes of the DNA-sensing pathway. G – H Representative flow analysis of CD3 + CD4 + T cells and CD3 + CD8 + T cells in tumor tissues. I – J Representative fluorescent images of CD3 + CD4 + T cells and CD3 + CD8 + T cells in tumor tissues. (n = 6, scale bars:100 μm)

    Article Snippet: GAPDH antibody (#ab8245, 1:3000) was purchased from Abcam. p-TBK1(Ser172) antibody (#5483,1:1000), p-IRF3(Ser386) (#37829, 1:1000) were purchased from Cell Signaling Technology.

    Techniques: In Vivo, Activation Assay, Quantitative RT-PCR