clear cell renal 429 carcinoma line 786 o (ATCC)
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clear cell renal 429 carcinoma line 786 o
Clear Cell Renal 429 Carcinoma Line 786 O, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 2299 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/786+o/786-O/pm42888846-174-17-36
Average 99 stars, based on 2299 article reviews
Clear Cell Renal 429 Carcinoma Line 786 O, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 2299 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/786+o/786-O/pm42888846-174-17-36
Average 99 stars, based on 2299 article reviews
clear cell renal 429 carcinoma line 786 o - by Bioz Stars,
2026-11
99/100 stars
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Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies P-MET-Y1234/1235 Cell Signaling Technology Cat# 3077; RRID: AB_2143886 Total MET Cell Signaling Technology Cat# 3148; RRID: AB_2143834 Total MET R&D Systems Cat# AF276; RRID: AB_355289 MET-PE R&D Systems Cat# FAB3582P; RRID: AB_357005 gamma-H2AX-S139 Cell Signaling Technology Cat# 9718; RRID: AB_2118009 H3-HRP Abcam Cat# ab21054; RRID: AB_446995 Actin-HRP Abcam Cat# ab207674; RRID: AB_2868347 P-AKT-S473 Cell Signaling Technology Cat# 9271; RRID: AB_329825 Total AKT Cell Signaling Technology Cat# 9272; RRID: AB_329827 ERK1/2-P-T202/Y204 Cell Signaling Technology Cat# 9101; RRID: AB_331646 Total ERK1/2 Cell Signaling Technology Cat# 9102; RRID: AB_330744 c-Myc Abcam Cat# ab32072; RRID: AB_731658 E-Cadherin Abcam Cat# ab40772; RRID: AB_731504 ACTA2 Sigma-Aldrich Cat# A2547; RRID: AB_476701 ETV1 Abcam Cat# ab314874 FGFR1 Cell Signaling Technology Cat# 9740; RRID: AB_11178516 P-FGFR1-Y653/654 Cell Signaling Technology Cat# 52928; RRID: AB_2799398 FRS2-P-Y436 Cell Signaling Technology Cat# 3861; RRID: AB_2092546 Anti-rabbit IgG-HRP Cell Signaling Technology Cat# 7074; RRID: AB_2099233 Anti-mouse IgG-HRP Cell Signaling Technology Cat# 7076; RRID: AB_330924 Anti-goat IgG-AlexaFluor 488 Thermo Fisher Scientific Cat# A11055; RRID: AB_2534102 Anti-rabbit IgG-AlexaFluor 647 Thermo Fisher Scientific Cat# A21245; RRID: AB_2535813 Anti-mouse IgG-AlexaFluor 555 Thermo Fisher Scientific Cat# A21422; RRID: AB_2535844 Chemicals, peptides, and recombinant proteins Recombinant human HGF R&D Systems Cat# 294-HGN/CF (Continued on next page) 16 Cell Reports 45, 118145, October 27, 2026 .. REAGENT or RESOURCE SOURCE IDENTIFIER Recombinant human FGF2 R&D Systems Cat# 3718-FB Cycloheximide Sigma-Aldrich Cat# 18079 Blasticidin InvivoGen Cat# ant-bl-05 Tepotinib Selleckchem Cat# S7067 AZD4547 Selleckchem Cat# S2801 TRIzol Reagent Thermo Fisher Scientific Cat# 15596026 Critical commercial assays Nano-Glo Dual-Luciferase Reporter Assay System Promega Cat# N1610 CyQUANT Cell Proliferation Assay Kit Thermo Fisher Cat# C35011 Maxwell RSC Blood DNA Kit Promega Cat# AS1400 Maxwell RSC miRNA Kit Promega Cat# AS1460 Zero Blunt TOPO PCR Cloning Kit Thermo Fisher Cat# 450031 Deposited data AACR Project GENIE v17 AACR https://www.aacr.org/professionals/research/ aacr-project-genie/ TCGA fusion dataset NCI GDC https://portal.gdc.cancer.gov Raw data and analysis scripts This study https://doi.org/10.5281/zenodo.21804107 Experimental models: Cell lines EKVX (H. sapiens) NCI RRID: CVCL_1195 HT-29 (H. sapiens) ATCC RRID: CVCL_0320 SW948 (H. sapiens) ATCC RRID: CVCL_0632 CAPAN-1 (H. sapiens) ATCC RRID: CVCL_0237 Luciferase:Article Title: Untranslated region rewiring defines a novel class of oncogene fusions. Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies P-MET-Y1234/1235 Cell Signaling Technology Cat# 3077; RRID: AB_2143886 Total MET Cell Signaling Technology Cat# 3148; RRID: AB_2143834 Total MET R&D Systems Cat# AF276; RRID: AB_355289 MET-PE R&D Systems Cat# FAB3582P; RRID: AB_357005 gamma-H2AX-S139 Cell Signaling Technology Cat# 9718; RRID: AB_2118009 H3-HRP Abcam Cat# ab21054; RRID: AB_446995 Actin-HRP Abcam Cat# ab207674; RRID: AB_2868347 P-AKT-S473 Cell Signaling Technology Cat# 9271; RRID: AB_329825 Total AKT Cell Signaling Technology Cat# 9272; RRID: AB_329827 ERK1/2-P-T202/Y204 Cell Signaling Technology Cat# 9101; RRID: AB_331646 Total ERK1/2 Cell Signaling Technology Cat# 9102; RRID: AB_330744 c-Myc Abcam Cat# ab32072; RRID: AB_731658 E-Cadherin Abcam Cat# ab40772; RRID: AB_731504 ACTA2 Sigma-Aldrich Cat# A2547; RRID: AB_476701 ETV1 Abcam Cat# ab314874 FGFR1 Cell Signaling Technology Cat# 9740; RRID: AB_11178516 P-FGFR1-Y653/654 Cell Signaling Technology Cat# 52928; RRID: AB_2799398 FRS2-P-Y436 Cell Signaling Technology Cat# 3861; RRID: AB_2092546 Anti-rabbit IgG-HRP Cell Signaling Technology Cat# 7074; RRID: AB_2099233 Anti-mouse IgG-HRP Cell Signaling Technology Cat# 7076; RRID: AB_330924 Anti-goat IgG-AlexaFluor 488 Thermo Fisher Scientific Cat# A11055; RRID: AB_2534102 Anti-rabbit IgG-AlexaFluor 647 Thermo Fisher Scientific Cat# A21245; RRID: AB_2535813 Anti-mouse IgG-AlexaFluor 555 Thermo Fisher Scientific Cat# A21422; RRID: AB_2535844 Chemicals, peptides, and recombinant proteins Recombinant human HGF R&D Systems Cat# 294-HGN/CF (Continued on next page) 16 Cell Reports 45, 118145, October 27, 2026 .. REAGENT or RESOURCE SOURCE IDENTIFIER Recombinant human FGF2 R&D Systems Cat# 3718-FB Cycloheximide Sigma-Aldrich Cat# 18079 Blasticidin InvivoGen Cat# ant-bl-05 Tepotinib Selleckchem Cat# S7067 AZD4547 Selleckchem Cat# S2801 TRIzol Reagent Thermo Fisher Scientific Cat# 15596026 Critical commercial assays Nano-Glo Dual-Luciferase Reporter Assay System Promega Cat# N1610 CyQUANT Cell Proliferation Assay Kit Thermo Fisher Cat# C35011 Maxwell RSC Blood DNA Kit Promega Cat# AS1400 Maxwell RSC miRNA Kit Promega Cat# AS1460 Zero Blunt TOPO PCR Cloning Kit Thermo Fisher Cat# 450031 Deposited data AACR Project GENIE v17 AACR https://www.aacr.org/professionals/research/ aacr-project-genie/ TCGA fusion dataset NCI GDC https://portal.gdc.cancer.gov Raw data and analysis scripts This study https://doi.org/10.5281/zenodo.21804107 Experimental models: Cell lines EKVX (H. sapiens) NCI RRID: CVCL_1195 HT-29 (H. sapiens) ATCC RRID: CVCL_0320 SW948 (H. sapiens) ATCC RRID: CVCL_0632 CAPAN-1 (H. sapiens) ATCC RRID: CVCL_0237 CyQUANT Assay:Article Title: Untranslated region rewiring defines a novel class of oncogene fusions. Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies P-MET-Y1234/1235 Cell Signaling Technology Cat# 3077; RRID: AB_2143886 Total MET Cell Signaling Technology Cat# 3148; RRID: AB_2143834 Total MET R&D Systems Cat# AF276; RRID: AB_355289 MET-PE R&D Systems Cat# FAB3582P; RRID: AB_357005 gamma-H2AX-S139 Cell Signaling Technology Cat# 9718; RRID: AB_2118009 H3-HRP Abcam Cat# ab21054; RRID: AB_446995 Actin-HRP Abcam Cat# ab207674; RRID: AB_2868347 P-AKT-S473 Cell Signaling Technology Cat# 9271; RRID: AB_329825 Total AKT Cell Signaling Technology Cat# 9272; RRID: AB_329827 ERK1/2-P-T202/Y204 Cell Signaling Technology Cat# 9101; RRID: AB_331646 Total ERK1/2 Cell Signaling Technology Cat# 9102; RRID: AB_330744 c-Myc Abcam Cat# ab32072; RRID: AB_731658 E-Cadherin Abcam Cat# ab40772; RRID: AB_731504 ACTA2 Sigma-Aldrich Cat# A2547; RRID: AB_476701 ETV1 Abcam Cat# ab314874 FGFR1 Cell Signaling Technology Cat# 9740; RRID: AB_11178516 P-FGFR1-Y653/654 Cell Signaling Technology Cat# 52928; RRID: AB_2799398 FRS2-P-Y436 Cell Signaling Technology Cat# 3861; RRID: AB_2092546 Anti-rabbit IgG-HRP Cell Signaling Technology Cat# 7074; RRID: AB_2099233 Anti-mouse IgG-HRP Cell Signaling Technology Cat# 7076; RRID: AB_330924 Anti-goat IgG-AlexaFluor 488 Thermo Fisher Scientific Cat# A11055; RRID: AB_2534102 Anti-rabbit IgG-AlexaFluor 647 Thermo Fisher Scientific Cat# A21245; RRID: AB_2535813 Anti-mouse IgG-AlexaFluor 555 Thermo Fisher Scientific Cat# A21422; RRID: AB_2535844 Chemicals, peptides, and recombinant proteins Recombinant human HGF R&D Systems Cat# 294-HGN/CF (Continued on next page) 16 Cell Reports 45, 118145, October 27, 2026 .. REAGENT or RESOURCE SOURCE IDENTIFIER Recombinant human FGF2 R&D Systems Cat# 3718-FB Cycloheximide Sigma-Aldrich Cat# 18079 Blasticidin InvivoGen Cat# ant-bl-05 Tepotinib Selleckchem Cat# S7067 AZD4547 Selleckchem Cat# S2801 TRIzol Reagent Thermo Fisher Scientific Cat# 15596026 Critical commercial assays Nano-Glo Dual-Luciferase Reporter Assay System Promega Cat# N1610 CyQUANT Cell Proliferation Assay Kit Thermo Fisher Cat# C35011 Maxwell RSC Blood DNA Kit Promega Cat# AS1400 Maxwell RSC miRNA Kit Promega Cat# AS1460 Zero Blunt TOPO PCR Cloning Kit Thermo Fisher Cat# 450031 Deposited data AACR Project GENIE v17 AACR https://www.aacr.org/professionals/research/ aacr-project-genie/ TCGA fusion dataset NCI GDC https://portal.gdc.cancer.gov Raw data and analysis scripts This study https://doi.org/10.5281/zenodo.21804107 Experimental models: Cell lines EKVX (H. sapiens) NCI RRID: CVCL_1195 HT-29 (H. sapiens) ATCC RRID: CVCL_0320 SW948 (H. sapiens) ATCC RRID: CVCL_0632 CAPAN-1 (H. sapiens) ATCC RRID: CVCL_0237 Proliferation Assay:Article Title: Untranslated region rewiring defines a novel class of oncogene fusions. Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies P-MET-Y1234/1235 Cell Signaling Technology Cat# 3077; RRID: AB_2143886 Total MET Cell Signaling Technology Cat# 3148; RRID: AB_2143834 Total MET R&D Systems Cat# AF276; RRID: AB_355289 MET-PE R&D Systems Cat# FAB3582P; RRID: AB_357005 gamma-H2AX-S139 Cell Signaling Technology Cat# 9718; RRID: AB_2118009 H3-HRP Abcam Cat# ab21054; RRID: AB_446995 Actin-HRP Abcam Cat# ab207674; RRID: AB_2868347 P-AKT-S473 Cell Signaling Technology Cat# 9271; RRID: AB_329825 Total AKT Cell Signaling Technology Cat# 9272; RRID: AB_329827 ERK1/2-P-T202/Y204 Cell Signaling Technology Cat# 9101; RRID: AB_331646 Total ERK1/2 Cell Signaling Technology Cat# 9102; RRID: AB_330744 c-Myc Abcam Cat# ab32072; RRID: AB_731658 E-Cadherin Abcam Cat# ab40772; RRID: AB_731504 ACTA2 Sigma-Aldrich Cat# A2547; RRID: AB_476701 ETV1 Abcam Cat# ab314874 FGFR1 Cell Signaling Technology Cat# 9740; RRID: AB_11178516 P-FGFR1-Y653/654 Cell Signaling Technology Cat# 52928; RRID: AB_2799398 FRS2-P-Y436 Cell Signaling Technology Cat# 3861; RRID: AB_2092546 Anti-rabbit IgG-HRP Cell Signaling Technology Cat# 7074; RRID: AB_2099233 Anti-mouse IgG-HRP Cell Signaling Technology Cat# 7076; RRID: AB_330924 Anti-goat IgG-AlexaFluor 488 Thermo Fisher Scientific Cat# A11055; RRID: AB_2534102 Anti-rabbit IgG-AlexaFluor 647 Thermo Fisher Scientific Cat# A21245; RRID: AB_2535813 Anti-mouse IgG-AlexaFluor 555 Thermo Fisher Scientific Cat# A21422; RRID: AB_2535844 Chemicals, peptides, and recombinant proteins Recombinant human HGF R&D Systems Cat# 294-HGN/CF (Continued on next page) 16 Cell Reports 45, 118145, October 27, 2026 .. REAGENT or RESOURCE SOURCE IDENTIFIER Recombinant human FGF2 R&D Systems Cat# 3718-FB Cycloheximide Sigma-Aldrich Cat# 18079 Blasticidin InvivoGen Cat# ant-bl-05 Tepotinib Selleckchem Cat# S7067 AZD4547 Selleckchem Cat# S2801 TRIzol Reagent Thermo Fisher Scientific Cat# 15596026 Critical commercial assays Nano-Glo Dual-Luciferase Reporter Assay System Promega Cat# N1610 CyQUANT Cell Proliferation Assay Kit Thermo Fisher Cat# C35011 Maxwell RSC Blood DNA Kit Promega Cat# AS1400 Maxwell RSC miRNA Kit Promega Cat# AS1460 Zero Blunt TOPO PCR Cloning Kit Thermo Fisher Cat# 450031 Deposited data AACR Project GENIE v17 AACR https://www.aacr.org/professionals/research/ aacr-project-genie/ TCGA fusion dataset NCI GDC https://portal.gdc.cancer.gov Raw data and analysis scripts This study https://doi.org/10.5281/zenodo.21804107 Experimental models: Cell lines EKVX (H. sapiens) NCI RRID: CVCL_1195 HT-29 (H. sapiens) ATCC RRID: CVCL_0320 SW948 (H. sapiens) ATCC RRID: CVCL_0632 CAPAN-1 (H. sapiens) ATCC RRID: CVCL_0237 Polymerase Chain Reaction:Article Title: Untranslated region rewiring defines a novel class of oncogene fusions. Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies P-MET-Y1234/1235 Cell Signaling Technology Cat# 3077; RRID: AB_2143886 Total MET Cell Signaling Technology Cat# 3148; RRID: AB_2143834 Total MET R&D Systems Cat# AF276; RRID: AB_355289 MET-PE R&D Systems Cat# FAB3582P; RRID: AB_357005 gamma-H2AX-S139 Cell Signaling Technology Cat# 9718; RRID: AB_2118009 H3-HRP Abcam Cat# ab21054; RRID: AB_446995 Actin-HRP Abcam Cat# ab207674; RRID: AB_2868347 P-AKT-S473 Cell Signaling Technology Cat# 9271; RRID: AB_329825 Total AKT Cell Signaling Technology Cat# 9272; RRID: AB_329827 ERK1/2-P-T202/Y204 Cell Signaling Technology Cat# 9101; RRID: AB_331646 Total ERK1/2 Cell Signaling Technology Cat# 9102; RRID: AB_330744 c-Myc Abcam Cat# ab32072; RRID: AB_731658 E-Cadherin Abcam Cat# ab40772; RRID: AB_731504 ACTA2 Sigma-Aldrich Cat# A2547; RRID: AB_476701 ETV1 Abcam Cat# ab314874 FGFR1 Cell Signaling Technology Cat# 9740; RRID: AB_11178516 P-FGFR1-Y653/654 Cell Signaling Technology Cat# 52928; RRID: AB_2799398 FRS2-P-Y436 Cell Signaling Technology Cat# 3861; RRID: AB_2092546 Anti-rabbit IgG-HRP Cell Signaling Technology Cat# 7074; RRID: AB_2099233 Anti-mouse IgG-HRP Cell Signaling Technology Cat# 7076; RRID: AB_330924 Anti-goat IgG-AlexaFluor 488 Thermo Fisher Scientific Cat# A11055; RRID: AB_2534102 Anti-rabbit IgG-AlexaFluor 647 Thermo Fisher Scientific Cat# A21245; RRID: AB_2535813 Anti-mouse IgG-AlexaFluor 555 Thermo Fisher Scientific Cat# A21422; RRID: AB_2535844 Chemicals, peptides, and recombinant proteins Recombinant human HGF R&D Systems Cat# 294-HGN/CF (Continued on next page) 16 Cell Reports 45, 118145, October 27, 2026 .. REAGENT or RESOURCE SOURCE IDENTIFIER Recombinant human FGF2 R&D Systems Cat# 3718-FB Cycloheximide Sigma-Aldrich Cat# 18079 Blasticidin InvivoGen Cat# ant-bl-05 Tepotinib Selleckchem Cat# S7067 AZD4547 Selleckchem Cat# S2801 TRIzol Reagent Thermo Fisher Scientific Cat# 15596026 Critical commercial assays Nano-Glo Dual-Luciferase Reporter Assay System Promega Cat# N1610 CyQUANT Cell Proliferation Assay Kit Thermo Fisher Cat# C35011 Maxwell RSC Blood DNA Kit Promega Cat# AS1400 Maxwell RSC miRNA Kit Promega Cat# AS1460 Zero Blunt TOPO PCR Cloning Kit Thermo Fisher Cat# 450031 Deposited data AACR Project GENIE v17 AACR https://www.aacr.org/professionals/research/ aacr-project-genie/ TCGA fusion dataset NCI GDC https://portal.gdc.cancer.gov Raw data and analysis scripts This study https://doi.org/10.5281/zenodo.21804107 Experimental models: Cell lines EKVX (H. sapiens) NCI RRID: CVCL_1195 HT-29 (H. sapiens) ATCC RRID: CVCL_0320 SW948 (H. sapiens) ATCC RRID: CVCL_0632 CAPAN-1 (H. sapiens) ATCC RRID: CVCL_0237 Cloning:Article Title: Untranslated region rewiring defines a novel class of oncogene fusions. Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies P-MET-Y1234/1235 Cell Signaling Technology Cat# 3077; RRID: AB_2143886 Total MET Cell Signaling Technology Cat# 3148; RRID: AB_2143834 Total MET R&D Systems Cat# AF276; RRID: AB_355289 MET-PE R&D Systems Cat# FAB3582P; RRID: AB_357005 gamma-H2AX-S139 Cell Signaling Technology Cat# 9718; RRID: AB_2118009 H3-HRP Abcam Cat# ab21054; RRID: AB_446995 Actin-HRP Abcam Cat# ab207674; RRID: AB_2868347 P-AKT-S473 Cell Signaling Technology Cat# 9271; RRID: AB_329825 Total AKT Cell Signaling Technology Cat# 9272; RRID: AB_329827 ERK1/2-P-T202/Y204 Cell Signaling Technology Cat# 9101; RRID: AB_331646 Total ERK1/2 Cell Signaling Technology Cat# 9102; RRID: AB_330744 c-Myc Abcam Cat# ab32072; RRID: AB_731658 E-Cadherin Abcam Cat# ab40772; RRID: AB_731504 ACTA2 Sigma-Aldrich Cat# A2547; RRID: AB_476701 ETV1 Abcam Cat# ab314874 FGFR1 Cell Signaling Technology Cat# 9740; RRID: AB_11178516 P-FGFR1-Y653/654 Cell Signaling Technology Cat# 52928; RRID: AB_2799398 FRS2-P-Y436 Cell Signaling Technology Cat# 3861; RRID: AB_2092546 Anti-rabbit IgG-HRP Cell Signaling Technology Cat# 7074; RRID: AB_2099233 Anti-mouse IgG-HRP Cell Signaling Technology Cat# 7076; RRID: AB_330924 Anti-goat IgG-AlexaFluor 488 Thermo Fisher Scientific Cat# A11055; RRID: AB_2534102 Anti-rabbit IgG-AlexaFluor 647 Thermo Fisher Scientific Cat# A21245; RRID: AB_2535813 Anti-mouse IgG-AlexaFluor 555 Thermo Fisher Scientific Cat# A21422; RRID: AB_2535844 Chemicals, peptides, and recombinant proteins Recombinant human HGF R&D Systems Cat# 294-HGN/CF (Continued on next page) 16 Cell Reports 45, 118145, October 27, 2026 .. REAGENT or RESOURCE SOURCE IDENTIFIER Recombinant human FGF2 R&D Systems Cat# 3718-FB Cycloheximide Sigma-Aldrich Cat# 18079 Blasticidin InvivoGen Cat# ant-bl-05 Tepotinib Selleckchem Cat# S7067 AZD4547 Selleckchem Cat# S2801 TRIzol Reagent Thermo Fisher Scientific Cat# 15596026 Critical commercial assays Nano-Glo Dual-Luciferase Reporter Assay System Promega Cat# N1610 CyQUANT Cell Proliferation Assay Kit Thermo Fisher Cat# C35011 Maxwell RSC Blood DNA Kit Promega Cat# AS1400 Maxwell RSC miRNA Kit Promega Cat# AS1460 Zero Blunt TOPO PCR Cloning Kit Thermo Fisher Cat# 450031 Deposited data AACR Project GENIE v17 AACR https://www.aacr.org/professionals/research/ aacr-project-genie/ TCGA fusion dataset NCI GDC https://portal.gdc.cancer.gov Raw data and analysis scripts This study https://doi.org/10.5281/zenodo.21804107 Experimental models: Cell lines EKVX (H. sapiens) NCI RRID: CVCL_1195 HT-29 (H. sapiens) ATCC RRID: CVCL_0320 SW948 (H. sapiens) ATCC RRID: CVCL_0632 CAPAN-1 (H. sapiens) ATCC RRID: CVCL_0237 Analysis:Article Title: Untranslated region rewiring defines a novel class of oncogene fusions. Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies P-MET-Y1234/1235 Cell Signaling Technology Cat# 3077; RRID: AB_2143886 Total MET Cell Signaling Technology Cat# 3148; RRID: AB_2143834 Total MET R&D Systems Cat# AF276; RRID: AB_355289 MET-PE R&D Systems Cat# FAB3582P; RRID: AB_357005 gamma-H2AX-S139 Cell Signaling Technology Cat# 9718; RRID: AB_2118009 H3-HRP Abcam Cat# ab21054; RRID: AB_446995 Actin-HRP Abcam Cat# ab207674; RRID: AB_2868347 P-AKT-S473 Cell Signaling Technology Cat# 9271; RRID: AB_329825 Total AKT Cell Signaling Technology Cat# 9272; RRID: AB_329827 ERK1/2-P-T202/Y204 Cell Signaling Technology Cat# 9101; RRID: AB_331646 Total ERK1/2 Cell Signaling Technology Cat# 9102; RRID: AB_330744 c-Myc Abcam Cat# ab32072; RRID: AB_731658 E-Cadherin Abcam Cat# ab40772; RRID: AB_731504 ACTA2 Sigma-Aldrich Cat# A2547; RRID: AB_476701 ETV1 Abcam Cat# ab314874 FGFR1 Cell Signaling Technology Cat# 9740; RRID: AB_11178516 P-FGFR1-Y653/654 Cell Signaling Technology Cat# 52928; RRID: AB_2799398 FRS2-P-Y436 Cell Signaling Technology Cat# 3861; RRID: AB_2092546 Anti-rabbit IgG-HRP Cell Signaling Technology Cat# 7074; RRID: AB_2099233 Anti-mouse IgG-HRP Cell Signaling Technology Cat# 7076; RRID: AB_330924 Anti-goat IgG-AlexaFluor 488 Thermo Fisher Scientific Cat# A11055; RRID: AB_2534102 Anti-rabbit IgG-AlexaFluor 647 Thermo Fisher Scientific Cat# A21245; RRID: AB_2535813 Anti-mouse IgG-AlexaFluor 555 Thermo Fisher Scientific Cat# A21422; RRID: AB_2535844 Chemicals, peptides, and recombinant proteins Recombinant human HGF R&D Systems Cat# 294-HGN/CF (Continued on next page) 16 Cell Reports 45, 118145, October 27, 2026 .. REAGENT or RESOURCE SOURCE IDENTIFIER Recombinant human FGF2 R&D Systems Cat# 3718-FB Cycloheximide Sigma-Aldrich Cat# 18079 Blasticidin InvivoGen Cat# ant-bl-05 Tepotinib Selleckchem Cat# S7067 AZD4547 Selleckchem Cat# S2801 TRIzol Reagent Thermo Fisher Scientific Cat# 15596026 Critical commercial assays Nano-Glo Dual-Luciferase Reporter Assay System Promega Cat# N1610 CyQUANT Cell Proliferation Assay Kit Thermo Fisher Cat# C35011 Maxwell RSC Blood DNA Kit Promega Cat# AS1400 Maxwell RSC miRNA Kit Promega Cat# AS1460 Zero Blunt TOPO PCR Cloning Kit Thermo Fisher Cat# 450031 Deposited data AACR Project GENIE v17 AACR https://www.aacr.org/professionals/research/ aacr-project-genie/ TCGA fusion dataset NCI GDC https://portal.gdc.cancer.gov Raw data and analysis scripts This study https://doi.org/10.5281/zenodo.21804107 Experimental models: Cell lines EKVX (H. sapiens) NCI RRID: CVCL_1195 HT-29 (H. sapiens) ATCC RRID: CVCL_0320 SW948 (H. sapiens) ATCC RRID: CVCL_0632 CAPAN-1 (H. sapiens) ATCC RRID: CVCL_0237 DNA Sequencing:Article Title: Untranslated region rewiring defines a novel class of oncogene fusions. Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies P-MET-Y1234/1235 Cell Signaling Technology Cat# 3077; RRID: AB_2143886 Total MET Cell Signaling Technology Cat# 3148; RRID: AB_2143834 Total MET R&D Systems Cat# AF276; RRID: AB_355289 MET-PE R&D Systems Cat# FAB3582P; RRID: AB_357005 gamma-H2AX-S139 Cell Signaling Technology Cat# 9718; RRID: AB_2118009 H3-HRP Abcam Cat# ab21054; RRID: AB_446995 Actin-HRP Abcam Cat# ab207674; RRID: AB_2868347 P-AKT-S473 Cell Signaling Technology Cat# 9271; RRID: AB_329825 Total AKT Cell Signaling Technology Cat# 9272; RRID: AB_329827 ERK1/2-P-T202/Y204 Cell Signaling Technology Cat# 9101; RRID: AB_331646 Total ERK1/2 Cell Signaling Technology Cat# 9102; RRID: AB_330744 c-Myc Abcam Cat# ab32072; RRID: AB_731658 E-Cadherin Abcam Cat# ab40772; RRID: AB_731504 ACTA2 Sigma-Aldrich Cat# A2547; RRID: AB_476701 ETV1 Abcam Cat# ab314874 FGFR1 Cell Signaling Technology Cat# 9740; RRID: AB_11178516 P-FGFR1-Y653/654 Cell Signaling Technology Cat# 52928; RRID: AB_2799398 FRS2-P-Y436 Cell Signaling Technology Cat# 3861; RRID: AB_2092546 Anti-rabbit IgG-HRP Cell Signaling Technology Cat# 7074; RRID: AB_2099233 Anti-mouse IgG-HRP Cell Signaling Technology Cat# 7076; RRID: AB_330924 Anti-goat IgG-AlexaFluor 488 Thermo Fisher Scientific Cat# A11055; RRID: AB_2534102 Anti-rabbit IgG-AlexaFluor 647 Thermo Fisher Scientific Cat# A21245; RRID: AB_2535813 Anti-mouse IgG-AlexaFluor 555 Thermo Fisher Scientific Cat# A21422; RRID: AB_2535844 Chemicals, peptides, and recombinant proteins Recombinant human HGF R&D Systems Cat# 294-HGN/CF (Continued on next page) 16 Cell Reports 45, 118145, October 27, 2026 .. REAGENT or RESOURCE SOURCE IDENTIFIER Recombinant human FGF2 R&D Systems Cat# 3718-FB Cycloheximide Sigma-Aldrich Cat# 18079 Blasticidin InvivoGen Cat# ant-bl-05 Tepotinib Selleckchem Cat# S7067 AZD4547 Selleckchem Cat# S2801 TRIzol Reagent Thermo Fisher Scientific Cat# 15596026 Critical commercial assays Nano-Glo Dual-Luciferase Reporter Assay System Promega Cat# N1610 CyQUANT Cell Proliferation Assay Kit Thermo Fisher Cat# C35011 Maxwell RSC Blood DNA Kit Promega Cat# AS1400 Maxwell RSC miRNA Kit Promega Cat# AS1460 Zero Blunt TOPO PCR Cloning Kit Thermo Fisher Cat# 450031 Deposited data AACR Project GENIE v17 AACR https://www.aacr.org/professionals/research/ aacr-project-genie/ TCGA fusion dataset NCI GDC https://portal.gdc.cancer.gov Raw data and analysis scripts This study https://doi.org/10.5281/zenodo.21804107 Experimental models: Cell lines EKVX (H. sapiens) NCI RRID: CVCL_1195 HT-29 (H. sapiens) ATCC RRID: CVCL_0320 SW948 (H. sapiens) ATCC RRID: CVCL_0632 CAPAN-1 (H. sapiens) ATCC RRID: CVCL_0237 Control:Article Title: Untranslated region rewiring defines a novel class of oncogene fusions. Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies P-MET-Y1234/1235 Cell Signaling Technology Cat# 3077; RRID: AB_2143886 Total MET Cell Signaling Technology Cat# 3148; RRID: AB_2143834 Total MET R&D Systems Cat# AF276; RRID: AB_355289 MET-PE R&D Systems Cat# FAB3582P; RRID: AB_357005 gamma-H2AX-S139 Cell Signaling Technology Cat# 9718; RRID: AB_2118009 H3-HRP Abcam Cat# ab21054; RRID: AB_446995 Actin-HRP Abcam Cat# ab207674; RRID: AB_2868347 P-AKT-S473 Cell Signaling Technology Cat# 9271; RRID: AB_329825 Total AKT Cell Signaling Technology Cat# 9272; RRID: AB_329827 ERK1/2-P-T202/Y204 Cell Signaling Technology Cat# 9101; RRID: AB_331646 Total ERK1/2 Cell Signaling Technology Cat# 9102; RRID: AB_330744 c-Myc Abcam Cat# ab32072; RRID: AB_731658 E-Cadherin Abcam Cat# ab40772; RRID: AB_731504 ACTA2 Sigma-Aldrich Cat# A2547; RRID: AB_476701 ETV1 Abcam Cat# ab314874 FGFR1 Cell Signaling Technology Cat# 9740; RRID: AB_11178516 P-FGFR1-Y653/654 Cell Signaling Technology Cat# 52928; RRID: AB_2799398 FRS2-P-Y436 Cell Signaling Technology Cat# 3861; RRID: AB_2092546 Anti-rabbit IgG-HRP Cell Signaling Technology Cat# 7074; RRID: AB_2099233 Anti-mouse IgG-HRP Cell Signaling Technology Cat# 7076; RRID: AB_330924 Anti-goat IgG-AlexaFluor 488 Thermo Fisher Scientific Cat# A11055; RRID: AB_2534102 Anti-rabbit IgG-AlexaFluor 647 Thermo Fisher Scientific Cat# A21245; RRID: AB_2535813 Anti-mouse IgG-AlexaFluor 555 Thermo Fisher Scientific Cat# A21422; RRID: AB_2535844 Chemicals, peptides, and recombinant proteins Recombinant human HGF R&D Systems Cat# 294-HGN/CF (Continued on next page) 16 Cell Reports 45, 118145, October 27, 2026 .. REAGENT or RESOURCE SOURCE IDENTIFIER Recombinant human FGF2 R&D Systems Cat# 3718-FB Cycloheximide Sigma-Aldrich Cat# 18079 Blasticidin InvivoGen Cat# ant-bl-05 Tepotinib Selleckchem Cat# S7067 AZD4547 Selleckchem Cat# S2801 TRIzol Reagent Thermo Fisher Scientific Cat# 15596026 Critical commercial assays Nano-Glo Dual-Luciferase Reporter Assay System Promega Cat# N1610 CyQUANT Cell Proliferation Assay Kit Thermo Fisher Cat# C35011 Maxwell RSC Blood DNA Kit Promega Cat# AS1400 Maxwell RSC miRNA Kit Promega Cat# AS1460 Zero Blunt TOPO PCR Cloning Kit Thermo Fisher Cat# 450031 Deposited data AACR Project GENIE v17 AACR https://www.aacr.org/professionals/research/ aacr-project-genie/ TCGA fusion dataset NCI GDC https://portal.gdc.cancer.gov Raw data and analysis scripts This study https://doi.org/10.5281/zenodo.21804107 Experimental models: Cell lines EKVX (H. sapiens) NCI RRID: CVCL_1195 HT-29 (H. sapiens) ATCC RRID: CVCL_0320 SW948 (H. sapiens) ATCC RRID: CVCL_0632 CAPAN-1 (H. sapiens) ATCC RRID: CVCL_0237 |