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Validation of the regulatory function of NFKB1 and the prognostic relevance of IFN‐Mac_CXCL9 and Angio‐Mac. (A and B) Bar plots showing VEGFA secretion and expression in THP‐1 derived M2 macrophages after NFKB1 knockout (A) or treatment with an <t>IKK</t> <t>inhibitor–BAY</t> 11‐7082 (B). (C‐D) Representative images of mIHC staining for IFN‐Mac_CXCL9 (C) using CD68, CXCL9 and PITX1 and Angio‐Mac (D) using CD68, VCAN and NFKB1. The arrows indicate cells positive for all three markers. Scale bars, 100 µm.
Ikk Inhibitor Bay 11 7082, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ikk inhibitor bay 11 7082/product/MedChemExpress
Average 98 stars, based on 1 article reviews
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bay 11 7082  (MedChemExpress)
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Validation of the regulatory function of NFKB1 and the prognostic relevance of IFN‐Mac_CXCL9 and Angio‐Mac. (A and B) Bar plots showing VEGFA secretion and expression in THP‐1 derived M2 macrophages after NFKB1 knockout (A) or treatment with an <t>IKK</t> <t>inhibitor–BAY</t> 11‐7082 (B). (C‐D) Representative images of mIHC staining for IFN‐Mac_CXCL9 (C) using CD68, CXCL9 and PITX1 and Angio‐Mac (D) using CD68, VCAN and NFKB1. The arrows indicate cells positive for all three markers. Scale bars, 100 µm.
Bay 11 7082, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bay 11 7082/product/MedChemExpress
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Validation of the regulatory function of NFKB1 and the prognostic relevance of IFN‐Mac_CXCL9 and Angio‐Mac. (A and B) Bar plots showing VEGFA secretion and expression in THP‐1 derived M2 macrophages after NFKB1 knockout (A) or treatment with an <t>IKK</t> <t>inhibitor–BAY</t> 11‐7082 (B). (C‐D) Representative images of mIHC staining for IFN‐Mac_CXCL9 (C) using CD68, CXCL9 and PITX1 and Angio‐Mac (D) using CD68, VCAN and NFKB1. The arrows indicate cells positive for all three markers. Scale bars, 100 µm.
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Validation of the regulatory function of NFKB1 and the prognostic relevance of IFN‐Mac_CXCL9 and Angio‐Mac. (A and B) Bar plots showing VEGFA secretion and expression in THP‐1 derived M2 macrophages after NFKB1 knockout (A) or treatment with an <t>IKK</t> <t>inhibitor–BAY</t> 11‐7082 (B). (C‐D) Representative images of mIHC staining for IFN‐Mac_CXCL9 (C) using CD68, CXCL9 and PITX1 and Angio‐Mac (D) using CD68, VCAN and NFKB1. The arrows indicate cells positive for all three markers. Scale bars, 100 µm.
Bay11 7082, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bay11 7082/product/MedChemExpress
Average 98 stars, based on 1 article reviews
bay11 7082 - by Bioz Stars, 2025-12
98/100 stars
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bay  (MedChemExpress)
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Validation of the regulatory function of NFKB1 and the prognostic relevance of IFN‐Mac_CXCL9 and Angio‐Mac. (A and B) Bar plots showing VEGFA secretion and expression in THP‐1 derived M2 macrophages after NFKB1 knockout (A) or treatment with an <t>IKK</t> <t>inhibitor–BAY</t> 11‐7082 (B). (C‐D) Representative images of mIHC staining for IFN‐Mac_CXCL9 (C) using CD68, CXCL9 and PITX1 and Angio‐Mac (D) using CD68, VCAN and NFKB1. The arrows indicate cells positive for all three markers. Scale bars, 100 µm.
Bay, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bay/product/MedChemExpress
Average 98 stars, based on 1 article reviews
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nf κb inhibitor  (MedChemExpress)
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MedChemExpress nf κb inhibitor
Validation of the regulatory function of NFKB1 and the prognostic relevance of IFN‐Mac_CXCL9 and Angio‐Mac. (A and B) Bar plots showing VEGFA secretion and expression in THP‐1 derived M2 macrophages after NFKB1 knockout (A) or treatment with an <t>IKK</t> <t>inhibitor–BAY</t> 11‐7082 (B). (C‐D) Representative images of mIHC staining for IFN‐Mac_CXCL9 (C) using CD68, CXCL9 and PITX1 and Angio‐Mac (D) using CD68, VCAN and NFKB1. The arrows indicate cells positive for all three markers. Scale bars, 100 µm.
Nf κb Inhibitor, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Validation of the regulatory function of NFKB1 and the prognostic relevance of IFN‐Mac_CXCL9 and Angio‐Mac. (A and B) Bar plots showing VEGFA secretion and expression in THP‐1 derived M2 macrophages after NFKB1 knockout (A) or treatment with an IKK inhibitor–BAY 11‐7082 (B). (C‐D) Representative images of mIHC staining for IFN‐Mac_CXCL9 (C) using CD68, CXCL9 and PITX1 and Angio‐Mac (D) using CD68, VCAN and NFKB1. The arrows indicate cells positive for all three markers. Scale bars, 100 µm.

Journal: Clinical and Translational Medicine

Article Title: Single‐cell landscape of the tumour immune microenvironment in human gynaecologic malignancies

doi: 10.1002/ctm2.70538

Figure Lengend Snippet: Validation of the regulatory function of NFKB1 and the prognostic relevance of IFN‐Mac_CXCL9 and Angio‐Mac. (A and B) Bar plots showing VEGFA secretion and expression in THP‐1 derived M2 macrophages after NFKB1 knockout (A) or treatment with an IKK inhibitor–BAY 11‐7082 (B). (C‐D) Representative images of mIHC staining for IFN‐Mac_CXCL9 (C) using CD68, CXCL9 and PITX1 and Angio‐Mac (D) using CD68, VCAN and NFKB1. The arrows indicate cells positive for all three markers. Scale bars, 100 µm.

Article Snippet: M2 macrophages were derived from M0 cells via IL‐4 (20 ng/mL, 200‐04; Sigma–Aldrich) and IL‐13 (20 ng/mL, 200‐13; PeproTech) treatment for 48 h, followed by treatment with the IKK inhibitor BAY 11‐7082 (20 μM, HY‐13453, MCE) for another 48 h. VEGFA levels in the culture supernatants were measured via ELISA (ABclonal RK00023), and total RNA was extracted for qPCR analysis.

Techniques: Biomarker Discovery, Expressing, Derivative Assay, Knock-Out, Staining