gcf 000393975 1  (ATCC)

Journal: Translational Andrology and Urology

Article Title: Identifying prognostic signatures in the microenvironment of prostate cancer

doi: 10.21037/tau-21-819

Figure Lengend Snippet: Basic information of datasets of PCa patients

Article Snippet: Among the 477 samples, 471 samples had SNP6 copy number segments available from https://firebrowse.org/ . table ft1 table-wrap mode="anchored" t5 caption a7 Series accession numbers Platform No. of patients AJCC_Stage Age, mean [min, max] Region Survival outcome TCGA-PRAD Illumina RNAseq 477 NA 61.6 [42, 79] NA DFS {"type":"entrez-geo","attrs":{"text":"GSE70770","term_id":"70770"}} GSE70770 Illumina HumanHT-12 V4.0 expression beadchip 111 NA 60.5 [41, 73] UK RFS Open in a separate window PCa, prostate cancer; DFS, disease-free survival; RFS, relapse-free survival; NA, not available. caption a8 Basic information of datasets of PCa patients

Techniques: Expressing

Journal: Translational Andrology and Urology

Article Title: Identifying prognostic signatures in the microenvironment of prostate cancer

doi: 10.21037/tau-21-819

Figure Lengend Snippet: he somatic genome characteristics of the TMEscore-related phenotypes in PCa. The distribution of frequently mutated genes in the high TMEscore group (A) and low TMEscore group (B) in PCa. Different colors indicate different alterations. The top barplot indicates TMB, TMEscore, and DFS per patient, and the left barplot shows the mutation frequency of each gene in separate TMEscore groups. The patient annotations show the TMEscores, TCGA molecular subtypes, TMEscore, gender, and survival status. (C) The VAFs of frequently mutated genes in the high TMEscore and low TMEscore groups. Within each group, the scattered dots represent the mean value of signature genes. The thick line represents the median value. (D) Violin plot showing the TMEscores in groups with different microsatellite instability (MSI) status. The Kruskal–Wallis test was used to compare the differences between the two groups. Mutational signatures are associated with the high TMEscore group (E) and low TMEscore group (F). TME, tumor microenvironment; PCa, prostate cancer; TCGA, The cancer genome atlas; TMB, tumor mutational burden; DEGs, differentially expressed genes; DFS, disease-free survival.

Article Snippet: Among the 477 samples, 471 samples had SNP6 copy number segments available from https://firebrowse.org/ . table ft1 table-wrap mode="anchored" t5 caption a7 Series accession numbers Platform No. of patients AJCC_Stage Age, mean [min, max] Region Survival outcome TCGA-PRAD Illumina RNAseq 477 NA 61.6 [42, 79] NA DFS {"type":"entrez-geo","attrs":{"text":"GSE70770","term_id":"70770"}} GSE70770 Illumina HumanHT-12 V4.0 expression beadchip 111 NA 60.5 [41, 73] UK RFS Open in a separate window PCa, prostate cancer; DFS, disease-free survival; RFS, relapse-free survival; NA, not available. caption a8 Basic information of datasets of PCa patients

Techniques: Mutagenesis