murine sarcoma 180 tumor cells s180  (ATCC)


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    ATCC murine sarcoma 180 tumor cells s180
    Viability of the <t> S180 </t> tumor cell line and the L929 normal cell line in the presence of ruthenium amino acid complexes and cisplatin.
    Murine Sarcoma 180 Tumor Cells S180, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 93 stars, based on 1 article reviews
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    murine sarcoma 180 tumor cells s180 - by Bioz Stars, 2023-03
    93/100 stars

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    1) Product Images from "Cytoxicity and Apoptotic Mechanism of Ruthenium(II) Amino Acid Complexes in Sarcoma-180 Tumor Cells"

    Article Title: Cytoxicity and Apoptotic Mechanism of Ruthenium(II) Amino Acid Complexes in Sarcoma-180 Tumor Cells

    Journal: PLoS ONE

    doi: 10.1371/journal.pone.0105865

    Viability of the S180 tumor cell line and the L929 normal cell line in the presence of ruthenium amino acid complexes and cisplatin.
    Figure Legend Snippet: Viability of the S180 tumor cell line and the L929 normal cell line in the presence of ruthenium amino acid complexes and cisplatin.

    Techniques Used:

    S180 cells were treated with the complex at the indicated concentrations for 24 h. The data are expressed as the means ± SD of two individual experiments; *p<0.05 and **p<0.01 compared with the control.
    Figure Legend Snippet: S180 cells were treated with the complex at the indicated concentrations for 24 h. The data are expressed as the means ± SD of two individual experiments; *p<0.05 and **p<0.01 compared with the control.

    Techniques Used:

    Proposed apoptotic signaling pathways triggered by complex 2 in S180 tumor cells.
    Figure Legend Snippet: Proposed apoptotic signaling pathways triggered by complex 2 in S180 tumor cells.

    Techniques Used:

    murine sarcoma 180 tumor cells s180  (ATCC)


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    ATCC murine sarcoma 180 tumor cells s180
    Viability of the <t> S180 </t> tumor cell line and the L929 normal cell line in the presence of ruthenium amino acid complexes and cisplatin.
    Murine Sarcoma 180 Tumor Cells S180, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/murine sarcoma 180 tumor cells s180/product/ATCC
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    murine sarcoma 180 tumor cells s180 - by Bioz Stars, 2023-03
    93/100 stars

    Images

    1) Product Images from "Cytoxicity and Apoptotic Mechanism of Ruthenium(II) Amino Acid Complexes in Sarcoma-180 Tumor Cells"

    Article Title: Cytoxicity and Apoptotic Mechanism of Ruthenium(II) Amino Acid Complexes in Sarcoma-180 Tumor Cells

    Journal: PLoS ONE

    doi: 10.1371/journal.pone.0105865

    Viability of the S180 tumor cell line and the L929 normal cell line in the presence of ruthenium amino acid complexes and cisplatin.
    Figure Legend Snippet: Viability of the S180 tumor cell line and the L929 normal cell line in the presence of ruthenium amino acid complexes and cisplatin.

    Techniques Used:

    S180 cells were treated with the complex at the indicated concentrations for 24 h. The data are expressed as the means ± SD of two individual experiments; *p<0.05 and **p<0.01 compared with the control.
    Figure Legend Snippet: S180 cells were treated with the complex at the indicated concentrations for 24 h. The data are expressed as the means ± SD of two individual experiments; *p<0.05 and **p<0.01 compared with the control.

    Techniques Used:

    Proposed apoptotic signaling pathways triggered by complex 2 in S180 tumor cells.
    Figure Legend Snippet: Proposed apoptotic signaling pathways triggered by complex 2 in S180 tumor cells.

    Techniques Used:

    s180 sarcoma cell line  (ATCC)


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    ATCC s180 sarcoma cell line
    The SR/CR mice resisted the s.c. injection of <t>S180</t> cells, whereas the C57BL/6 mice developed tumors 8–30 days after s.c. injection of S180 cells which was at a significantly higher frequency (p<0.0001). SR/CR and C57BL/6 mice both developed tumors 8–14 days after the transplantation or s.c. injection of EL4 cells. SR/CR mice were inoculated i.p. with 8×10 5 J774A.1 cells and ascites developed 34–40 days later, and this resistance was significantly lower (p<0.0081) compared to the resistance of SR/CR mice to S180 cells.
    S180 Sarcoma Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    s180 sarcoma cell line - by Bioz Stars, 2023-03
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    1) Product Images from "Immune Cells from SR/CR Mice Induce the Regression of Established Tumors in BALB/c and C57BL/6 Mice"

    Article Title: Immune Cells from SR/CR Mice Induce the Regression of Established Tumors in BALB/c and C57BL/6 Mice

    Journal: PLoS ONE

    doi: 10.1371/journal.pone.0059995

    The SR/CR mice resisted the s.c. injection of S180 cells, whereas the C57BL/6 mice developed tumors 8–30 days after s.c. injection of S180 cells which was at a significantly higher frequency (p<0.0001). SR/CR and C57BL/6 mice both developed tumors 8–14 days after the transplantation or s.c. injection of EL4 cells. SR/CR mice were inoculated i.p. with 8×10 5 J774A.1 cells and ascites developed 34–40 days later, and this resistance was significantly lower (p<0.0081) compared to the resistance of SR/CR mice to S180 cells.
    Figure Legend Snippet: The SR/CR mice resisted the s.c. injection of S180 cells, whereas the C57BL/6 mice developed tumors 8–30 days after s.c. injection of S180 cells which was at a significantly higher frequency (p<0.0001). SR/CR and C57BL/6 mice both developed tumors 8–14 days after the transplantation or s.c. injection of EL4 cells. SR/CR mice were inoculated i.p. with 8×10 5 J774A.1 cells and ascites developed 34–40 days later, and this resistance was significantly lower (p<0.0081) compared to the resistance of SR/CR mice to S180 cells.

    Techniques Used: Injection, Transplantation Assay

    (A) Survival of S180-cancer susceptible C57BL/6 mice after AT. Two mice that received SR/CR-leukocytes and four mice that received C57BL/6 leukocytes were euthanized due to excessive S180 tumor burdens. (B) Tumor volumes after AT. Progressive tumor growth was observed in untreated C57BL/6 mice after the bilateral s.c. injection of 10 6 S180 cells in the axillary region. The growth reached a plateau approximately 20 days post tumor cell inoculation. One mouse was euthanized when one of its tumors exceeded 12 mm in diameter. The vertical line at 40 days represents the time point when mice with completely regressed tumors were injected i.p. with S180 cells. A one-way ANOVA analysis revealed a significant difference (p = 0.0005) in tumor size between the two groups of mice with either efficient or inefficient AT. Each point represents the mean and SEM. (C) The numbers and the composition of the transferred SR/CR and C57BL/6 (B6) derived leukocytes. There were no significant differences in the numbers of total leukocytes (splenocytes + peritoneal leukocytes) transferred from the SR/CR and C57BL/6 mice (p = 0.969). The numbers of peritoneal immune cells derived from the SR/CR and C57BL/6 mice were not significantly different (p = 0.721). T = total leukocytes. Per = peritoneal leukocytes.
    Figure Legend Snippet: (A) Survival of S180-cancer susceptible C57BL/6 mice after AT. Two mice that received SR/CR-leukocytes and four mice that received C57BL/6 leukocytes were euthanized due to excessive S180 tumor burdens. (B) Tumor volumes after AT. Progressive tumor growth was observed in untreated C57BL/6 mice after the bilateral s.c. injection of 10 6 S180 cells in the axillary region. The growth reached a plateau approximately 20 days post tumor cell inoculation. One mouse was euthanized when one of its tumors exceeded 12 mm in diameter. The vertical line at 40 days represents the time point when mice with completely regressed tumors were injected i.p. with S180 cells. A one-way ANOVA analysis revealed a significant difference (p = 0.0005) in tumor size between the two groups of mice with either efficient or inefficient AT. Each point represents the mean and SEM. (C) The numbers and the composition of the transferred SR/CR and C57BL/6 (B6) derived leukocytes. There were no significant differences in the numbers of total leukocytes (splenocytes + peritoneal leukocytes) transferred from the SR/CR and C57BL/6 mice (p = 0.969). The numbers of peritoneal immune cells derived from the SR/CR and C57BL/6 mice were not significantly different (p = 0.721). T = total leukocytes. Per = peritoneal leukocytes.

    Techniques Used: Injection, Derivative Assay

    (A) Fourteen days after inoculation, the tumor tissue was dense with mitotic figures, and no infiltration of immune cells was observed (HE stain, bar 20 µm). (B) A section of tumor tissue (TT) that reached the plateau phase of growth 22 days after inoculation. A large area of necrosis (N) was visible, but no infiltrating immune cells were present (HE stain, bar 20 µm). (C) Massive infiltration of PMNs in S180 tumors after AT of cancer-resistant SR/CR leukocytes to cancer susceptible C57BL/6 mice (representative sections, n = 8). Tumor tissue (TT) from a mouse with tumor regrowth showed large areas of infiltrating PMNs (PMN) and necrosis (N) (HE stain, bar 100 µm). (D) Tumor tissue (TT) from a mouse with tumor regrowth revealed the infiltration of PMNs (PMN) (HE stain, bar 20 µm). (E) The regression of tumor tissue (TT) in a cancer-susceptible C57BL/6 mouse after AT of SR/CR leukocytes. Large necrotic areas (N) in the tumor tissue were observed (HE stain, bar 100 µm). (F) An image of the same tumor as in C), showing a clear demarcation between the vital tumor tissue (TT) and the infiltrating PMNs (PMN), as well as large necrotic (N) areas (HE stain, bar 100 µm).
    Figure Legend Snippet: (A) Fourteen days after inoculation, the tumor tissue was dense with mitotic figures, and no infiltration of immune cells was observed (HE stain, bar 20 µm). (B) A section of tumor tissue (TT) that reached the plateau phase of growth 22 days after inoculation. A large area of necrosis (N) was visible, but no infiltrating immune cells were present (HE stain, bar 20 µm). (C) Massive infiltration of PMNs in S180 tumors after AT of cancer-resistant SR/CR leukocytes to cancer susceptible C57BL/6 mice (representative sections, n = 8). Tumor tissue (TT) from a mouse with tumor regrowth showed large areas of infiltrating PMNs (PMN) and necrosis (N) (HE stain, bar 100 µm). (D) Tumor tissue (TT) from a mouse with tumor regrowth revealed the infiltration of PMNs (PMN) (HE stain, bar 20 µm). (E) The regression of tumor tissue (TT) in a cancer-susceptible C57BL/6 mouse after AT of SR/CR leukocytes. Large necrotic areas (N) in the tumor tissue were observed (HE stain, bar 100 µm). (F) An image of the same tumor as in C), showing a clear demarcation between the vital tumor tissue (TT) and the infiltrating PMNs (PMN), as well as large necrotic (N) areas (HE stain, bar 100 µm).

    Techniques Used: H&E Stain

    The tumors in the group that received an AT from nonresistant controls (n = 6) grew exponentially, whereas the tumors in the group that received an AT from SR/CR mice (n = 6) regressed 30–40 days after AT. The tumors in the nonresistant control group were significantly larger (p = 0.0001). The vertical line at 60 days represents the time point when the mice with regressed tumors were injected i.p with S180 cells.
    Figure Legend Snippet: The tumors in the group that received an AT from nonresistant controls (n = 6) grew exponentially, whereas the tumors in the group that received an AT from SR/CR mice (n = 6) regressed 30–40 days after AT. The tumors in the nonresistant control group were significantly larger (p = 0.0001). The vertical line at 60 days represents the time point when the mice with regressed tumors were injected i.p with S180 cells.

    Techniques Used: Injection

    murine sarcoma 180  (ATCC)


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    ATCC murine sarcoma 180
    Murine Sarcoma 180, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    materials sarcoma 180 s 180 cells  (ATCC)


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    ATCC materials sarcoma 180 s 180 cells
    Materials Sarcoma 180 S 180 Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 93 stars, based on 1 article reviews
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    sarcoma 180  (ATCC)


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    ATCC sarcoma 180
    Sarcoma 180, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    sarcoma 180 cells  (ATCC)


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    ATCC sarcoma 180 cells
    Cytotoxicity in a RAW264.7; b HepG2; and c <t>Sarcoma−180</t> cell lines: 37 °C, 24 h. d TNF-α secretion, polymer concentration: 100 μg/mL, 37 °C, 8 h; e Effect of polymer concentration (P7, FB 30%) on TNF-α secretion: 37 °C, 8 h. Two-tailed unpaired t test were performed Ctrl vs 0.1 ( p < 0.0001), 0.1 vs 10 ( p < 0.0001), 10 vs 50 ( p < 0.0001), 50 vs 100 ( p < 0.0001), 100 vs 200 ( p < 0.0001), 200 vs 500 ( p < 0.0001), 500 vs 1000 ( p = 0.2078); f NO secretion, polymer concentration: 100 μg/mL, 37 °C, 24 h; g Effect of polymer concentration (P7, FB 30%) on NO secretion, polymer concentration: 100 μg/mL, 37 °C, 24 h. Two-tailed unpaired t test were performed Ctrl vs 0.1 ( p < 0.0001), 0.1 vs 10 ( p < 0.0001), 10 vs 50 ( p < 0.0001), 50 vs 100 ( p < 0.0001), 100 vs 200 ( p < 0.0001), 200 vs 500 ( p < 0.0001), 500 vs 1000 ( p = 0.0346); h Effect of M n (FB 30%) on TNF-α secretion, polymer concentration: 100 μg/mL, 37 °C, 8 h. Two-tailed unpaired t test were performed Ctrl vs 3600 ( p < 0.0001), 3600 vs 12,100 ( p < 0.0001), 12,100 vs 18,600 ( p < 0.0001), 18600 vs 27,500 ( p = 0.0136), 27,500 vs 46,100 ( p = 0.0521); i Effect of M n (FB 30%) on NO secretion, polymer concentration: 100 μg/mL, 37 °C, 24 h. Two-tailed unpaired t test were performed Ctrl vs 3600 ( p < 0.0001), 3600 vs 12,100 ( p < 0.0001), 12,100 vs 18,600 ( p < 0.0001), 18,600 vs 27,500 ( p = 0.0002), 27,500 vs 46,100 ( p < 0.0001). Unless otherwise stated, data are means ± SD of three independent experiments ( N = 3), and triplicates ( n = 3) per condition are used in each experiment. ns p > 0.05, * p ≤ 0.05, ** p ≤ 0.01, **** p ≤ 0.0001 compared to control ( a , c ) or adjacent treatment group using two-tailed unpaired t test. Abbreviations used: Ctrl = Control.
    Sarcoma 180 Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    1) Product Images from "Synthesis of bioactive (1→6)-β-glucose branched poly-amido-saccharides that stimulate and induce M1 polarization in macrophages"

    Article Title: Synthesis of bioactive (1→6)-β-glucose branched poly-amido-saccharides that stimulate and induce M1 polarization in macrophages

    Journal: Nature Communications

    doi: 10.1038/s41467-022-32346-5

    Cytotoxicity in a RAW264.7; b HepG2; and c Sarcoma−180 cell lines: 37 °C, 24 h. d TNF-α secretion, polymer concentration: 100 μg/mL, 37 °C, 8 h; e Effect of polymer concentration (P7, FB 30%) on TNF-α secretion: 37 °C, 8 h. Two-tailed unpaired t test were performed Ctrl vs 0.1 ( p < 0.0001), 0.1 vs 10 ( p < 0.0001), 10 vs 50 ( p < 0.0001), 50 vs 100 ( p < 0.0001), 100 vs 200 ( p < 0.0001), 200 vs 500 ( p < 0.0001), 500 vs 1000 ( p = 0.2078); f NO secretion, polymer concentration: 100 μg/mL, 37 °C, 24 h; g Effect of polymer concentration (P7, FB 30%) on NO secretion, polymer concentration: 100 μg/mL, 37 °C, 24 h. Two-tailed unpaired t test were performed Ctrl vs 0.1 ( p < 0.0001), 0.1 vs 10 ( p < 0.0001), 10 vs 50 ( p < 0.0001), 50 vs 100 ( p < 0.0001), 100 vs 200 ( p < 0.0001), 200 vs 500 ( p < 0.0001), 500 vs 1000 ( p = 0.0346); h Effect of M n (FB 30%) on TNF-α secretion, polymer concentration: 100 μg/mL, 37 °C, 8 h. Two-tailed unpaired t test were performed Ctrl vs 3600 ( p < 0.0001), 3600 vs 12,100 ( p < 0.0001), 12,100 vs 18,600 ( p < 0.0001), 18600 vs 27,500 ( p = 0.0136), 27,500 vs 46,100 ( p = 0.0521); i Effect of M n (FB 30%) on NO secretion, polymer concentration: 100 μg/mL, 37 °C, 24 h. Two-tailed unpaired t test were performed Ctrl vs 3600 ( p < 0.0001), 3600 vs 12,100 ( p < 0.0001), 12,100 vs 18,600 ( p < 0.0001), 18,600 vs 27,500 ( p = 0.0002), 27,500 vs 46,100 ( p < 0.0001). Unless otherwise stated, data are means ± SD of three independent experiments ( N = 3), and triplicates ( n = 3) per condition are used in each experiment. ns p > 0.05, * p ≤ 0.05, ** p ≤ 0.01, **** p ≤ 0.0001 compared to control ( a , c ) or adjacent treatment group using two-tailed unpaired t test. Abbreviations used: Ctrl = Control.
    Figure Legend Snippet: Cytotoxicity in a RAW264.7; b HepG2; and c Sarcoma−180 cell lines: 37 °C, 24 h. d TNF-α secretion, polymer concentration: 100 μg/mL, 37 °C, 8 h; e Effect of polymer concentration (P7, FB 30%) on TNF-α secretion: 37 °C, 8 h. Two-tailed unpaired t test were performed Ctrl vs 0.1 ( p < 0.0001), 0.1 vs 10 ( p < 0.0001), 10 vs 50 ( p < 0.0001), 50 vs 100 ( p < 0.0001), 100 vs 200 ( p < 0.0001), 200 vs 500 ( p < 0.0001), 500 vs 1000 ( p = 0.2078); f NO secretion, polymer concentration: 100 μg/mL, 37 °C, 24 h; g Effect of polymer concentration (P7, FB 30%) on NO secretion, polymer concentration: 100 μg/mL, 37 °C, 24 h. Two-tailed unpaired t test were performed Ctrl vs 0.1 ( p < 0.0001), 0.1 vs 10 ( p < 0.0001), 10 vs 50 ( p < 0.0001), 50 vs 100 ( p < 0.0001), 100 vs 200 ( p < 0.0001), 200 vs 500 ( p < 0.0001), 500 vs 1000 ( p = 0.0346); h Effect of M n (FB 30%) on TNF-α secretion, polymer concentration: 100 μg/mL, 37 °C, 8 h. Two-tailed unpaired t test were performed Ctrl vs 3600 ( p < 0.0001), 3600 vs 12,100 ( p < 0.0001), 12,100 vs 18,600 ( p < 0.0001), 18600 vs 27,500 ( p = 0.0136), 27,500 vs 46,100 ( p = 0.0521); i Effect of M n (FB 30%) on NO secretion, polymer concentration: 100 μg/mL, 37 °C, 24 h. Two-tailed unpaired t test were performed Ctrl vs 3600 ( p < 0.0001), 3600 vs 12,100 ( p < 0.0001), 12,100 vs 18,600 ( p < 0.0001), 18,600 vs 27,500 ( p = 0.0002), 27,500 vs 46,100 ( p < 0.0001). Unless otherwise stated, data are means ± SD of three independent experiments ( N = 3), and triplicates ( n = 3) per condition are used in each experiment. ns p > 0.05, * p ≤ 0.05, ** p ≤ 0.01, **** p ≤ 0.0001 compared to control ( a , c ) or adjacent treatment group using two-tailed unpaired t test. Abbreviations used: Ctrl = Control.

    Techniques Used: Concentration Assay, Two Tailed Test

    sarcoma 180 s180  (ATCC)


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    ATCC sarcoma 180 s180
    a Tumor growth curves among different treatment groups in sarcoma <t>S180</t> tumor recurrence model ( n = 6 mice). Saline; NP-P@Gel, blank nanoparticles and unmodified platelets co-loaded hydrogel; PLX-aPD-1@Gel, free PLX and aPD-1 co-loaded hydrogel; PLX-NP@Gel, PLX-NP loaded hydrogel; P-aPD-1@Gel, P-aPD-1 loaded hydrogel; PLX-NP+P-aPD-1, free PLX-NP and P-aPD-1; PLX-NP-P-aPD-1@Gel, PLX-NP and P-aPD-1 co-loaded hydrogel. The doses of PLX and aPD-1 were 5 mg/kg and 0.1 mg/kg, respectively. b The images of representative tumors after different treatments on day 21 ( n = 6 mice). c Survival curves of the mice in different treatment groups in the S180 tumor recurrence model ( n = 6 mice). Data were analyzed with Log-rank (Mantel-Cox) test, PLX-NP-P-aPD-1@Gel vs. PLX-NP+P-aPD-1: ** P = 0.0031. d Representative bioluminescence images of B16F10 tumor-bearing Rag −/− mice following different treatments on day 0, day 7, day 14, day 21 ( n = 5 mice). e Survival curves of the mice treated with different treatment groups in B16F10 tumor recurrence model in Rag −/− mice ( n = 5 mice). f Schematic illustration of the establishment and treatment strategy of a double tumor model. g Tumor growth curve of the distant tumor after different treatments (PLX-NP-P-aPD-1@Gel vs. PLX-NP+P-aPD-1: *** P < 0.0001). Data are presented as mean ± s.d. ( n = 6 mice) and analyzed with two-way ANOVA followed by Tukey’s multiple comparison test. Source data are provided as a Source Data file.
    Sarcoma 180 S180, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    sarcoma 180 s180 - by Bioz Stars, 2023-03
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    1) Product Images from "Depletion of tumor associated macrophages enhances local and systemic platelet-mediated anti-PD-1 delivery for post-surgery tumor recurrence treatment"

    Article Title: Depletion of tumor associated macrophages enhances local and systemic platelet-mediated anti-PD-1 delivery for post-surgery tumor recurrence treatment

    Journal: Nature Communications

    doi: 10.1038/s41467-022-29388-0

    a Tumor growth curves among different treatment groups in sarcoma S180 tumor recurrence model ( n = 6 mice). Saline; NP-P@Gel, blank nanoparticles and unmodified platelets co-loaded hydrogel; PLX-aPD-1@Gel, free PLX and aPD-1 co-loaded hydrogel; PLX-NP@Gel, PLX-NP loaded hydrogel; P-aPD-1@Gel, P-aPD-1 loaded hydrogel; PLX-NP+P-aPD-1, free PLX-NP and P-aPD-1; PLX-NP-P-aPD-1@Gel, PLX-NP and P-aPD-1 co-loaded hydrogel. The doses of PLX and aPD-1 were 5 mg/kg and 0.1 mg/kg, respectively. b The images of representative tumors after different treatments on day 21 ( n = 6 mice). c Survival curves of the mice in different treatment groups in the S180 tumor recurrence model ( n = 6 mice). Data were analyzed with Log-rank (Mantel-Cox) test, PLX-NP-P-aPD-1@Gel vs. PLX-NP+P-aPD-1: ** P = 0.0031. d Representative bioluminescence images of B16F10 tumor-bearing Rag −/− mice following different treatments on day 0, day 7, day 14, day 21 ( n = 5 mice). e Survival curves of the mice treated with different treatment groups in B16F10 tumor recurrence model in Rag −/− mice ( n = 5 mice). f Schematic illustration of the establishment and treatment strategy of a double tumor model. g Tumor growth curve of the distant tumor after different treatments (PLX-NP-P-aPD-1@Gel vs. PLX-NP+P-aPD-1: *** P < 0.0001). Data are presented as mean ± s.d. ( n = 6 mice) and analyzed with two-way ANOVA followed by Tukey’s multiple comparison test. Source data are provided as a Source Data file.
    Figure Legend Snippet: a Tumor growth curves among different treatment groups in sarcoma S180 tumor recurrence model ( n = 6 mice). Saline; NP-P@Gel, blank nanoparticles and unmodified platelets co-loaded hydrogel; PLX-aPD-1@Gel, free PLX and aPD-1 co-loaded hydrogel; PLX-NP@Gel, PLX-NP loaded hydrogel; P-aPD-1@Gel, P-aPD-1 loaded hydrogel; PLX-NP+P-aPD-1, free PLX-NP and P-aPD-1; PLX-NP-P-aPD-1@Gel, PLX-NP and P-aPD-1 co-loaded hydrogel. The doses of PLX and aPD-1 were 5 mg/kg and 0.1 mg/kg, respectively. b The images of representative tumors after different treatments on day 21 ( n = 6 mice). c Survival curves of the mice in different treatment groups in the S180 tumor recurrence model ( n = 6 mice). Data were analyzed with Log-rank (Mantel-Cox) test, PLX-NP-P-aPD-1@Gel vs. PLX-NP+P-aPD-1: ** P = 0.0031. d Representative bioluminescence images of B16F10 tumor-bearing Rag −/− mice following different treatments on day 0, day 7, day 14, day 21 ( n = 5 mice). e Survival curves of the mice treated with different treatment groups in B16F10 tumor recurrence model in Rag −/− mice ( n = 5 mice). f Schematic illustration of the establishment and treatment strategy of a double tumor model. g Tumor growth curve of the distant tumor after different treatments (PLX-NP-P-aPD-1@Gel vs. PLX-NP+P-aPD-1: *** P < 0.0001). Data are presented as mean ± s.d. ( n = 6 mice) and analyzed with two-way ANOVA followed by Tukey’s multiple comparison test. Source data are provided as a Source Data file.

    Techniques Used:

    sarcoma 180  (ATCC)


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    Bioz Manufacturer Symbol ATCC manufactures this product  
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    ATCC sarcoma 180
    Sarcoma 180, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/sarcoma 180/product/ATCC
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    sarcoma 180 - by Bioz Stars, 2023-03
    93/100 stars

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    murine sarcoma 180 tumor cells s180  (ATCC)


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    • 93
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    Structured Review

    ATCC murine sarcoma 180 tumor cells s180
    Murine Sarcoma 180 Tumor Cells S180, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/murine sarcoma 180 tumor cells s180/product/ATCC
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    murine sarcoma 180 tumor cells s180 - by Bioz Stars, 2023-03
    93/100 stars

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    sarcoma 180 cells  (ATCC)


    Bioz Verified Symbol ATCC is a verified supplier
    Bioz Manufacturer Symbol ATCC manufactures this product  
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    • 93
      Buy from Supplier

    Structured Review

    ATCC sarcoma 180 cells
    Sarcoma 180 Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/sarcoma 180 cells/product/ATCC
    Average 93 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    sarcoma 180 cells - by Bioz Stars, 2023-03
    93/100 stars

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