Journal: Aging (Albany NY)
Article Title: The protective effect of luteolin on the depression-related dry eye disorder through Sirt1/NF-κB/NLRP3 pathway
doi: 10.18632/aging.204479
Figure Lengend Snippet: Role of Sirt1 in the reduction of CUMS-induced depressive behavior by luteolin. ( A ) Sucrose preference rate of mice was determined by SPT. ( B ) The immobility time of mice was measured by TST. ( C ) Western Blot analysis of the expression of AC-NF-κB, NF-κB, GSDMD-N and GSDMD protein in hippocampal tissue. ( D ) Nisi staining of mice treated with EX-527. Data were analyzed by means ± SEM. Compared with blank group, ## P < 0.01; Comparison with model group * P < 0.05, ** P < 0.01, n = 9.
Article Snippet: EX-527 (CAS: 49843-98-3) was provided by Sigma Biotechnology Co., Ltd. (E7034, Sigma-Aldrich, USA).
Techniques: Western Blot, Expressing, Staining