Journal: mBio
Article Title: Genome-Wide Essentiality Analysis of Mycobacterium abscessus by Saturated Transposon Mutagenesis and Deep Sequencing
doi: 10.1128/mBio.01049-21
Figure Lengend Snippet: Homology comparison of essential genes among M. abscessus (Mab) ATCC 19977 T , M. tuberculosis (Mtb) H37Rv, and M. avium subsp. hominissuis (MAH) MAC109.
Article Snippet: A homology comparison between proteins encoded by annotated genes of M. abscessus ATCC 19977 T ( n = 4,920), M. tuberculosis H37Rv ( n = 4,018), and M. avium strain MAC109 ( n = 4,704) revealed that 44.1% (2,170/4,920) of M. abscessus genes shared common orthologs with both M. tuberculosis and M. avium genes, and small numbers of genes were only homologous to M. tuberculosis (2.5%, 122/4,920) or M. avium (9.7%, 477/4,920); 43.6% (2,145/4,920) of M. abscessus genes had no significant homology to M. tuberculosis or M. avium genes.
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