4 Cholesten 3 One, supplied by steraloids inc, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 92 stars, based on 1 article reviews
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1) Product Images from "\u201cProfiling Sterols in Cerebrotendinous Xanthomatosis: Utility of Girard Derivatization and High Resolution Exact Mass LC-ESI-MSn Analysis\u201d"
Article Title: \u201cProfiling Sterols in Cerebrotendinous Xanthomatosis: Utility of Girard Derivatization and High Resolution Exact Mass LC-ESI-MSn Analysis\u201d
Journal: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
Figure Legend Snippet: 7α,12α-Dihydroxy-4-cholesten-3-one and 7α,12α-dihydroxy-5β-cholestan-3-one present in plasma from untreated CTX patient
Figure Legend Snippet: 7α-Hydroxy-4-cholesten-3-one and 4-cholesten-3-one present in plasma from untreated CTX patient and cyp27A1 −/− mice
Techniques Used: Mouse Assay
Figure Legend Snippet: Fragmentation routes for GP-tagged 3-oxo-4-ene sterols illustrated by 4-cholesten-3-one
2) Product Images from "Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor"
Article Title: Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor
Journal: Proceedings of the National Academy of Sciences of the United States of America
Figure Legend Snippet: Hepatic mRNA expression levels of several enzymes involved in bile acid biosynthesis are altered in the Cyp27a1 −/− mouse. Relative hepatic RNA levels were determined by Northern analysis from male, mixed-strain, wild-type and Cyp27a1 −/− mice fed a standard rodent diet. The values shown in boxes represent the mean ± SEM of the fold change in mRNA levels ( n = 6 mice per genotype). Bile acid intermediates that would be predicted to accumulate upstream of CYP3A11 because of these changes in enzyme levels include the following: 1 , 7α-hydroxycholesterol (5-cholesten-3β,7α-diol); 2 , 7α-hydroxy-4-cholesten-3-one (4-cholesten-7α-ol-3-one); 3 , 5β-cholestan-3α,7α,12α-triol; 4 , 4-cholesten-3-one; and 5 , cholestanol (5α-cholestan-3β-ol).
Techniques Used: Expressing, Northern Blot, Mouse Assay
Article Title: A novel alkyne cholesterol to trace cellular cholesterol metabolism and localization [S]
Article Snippet: Deuterated d6-cholesterol, cholesterol-26,26,26,27,27,27-2 H6 , and 4-cholesten-3-one were from