voluntary running wheel activity  (TSE systems)


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    TSE systems voluntary running wheel activity
    Skeletal muscle integrity and mitochondrial biogenesis in male TG/Nrf2-Ko mice. ( A ) Grip strength of 24 wks old animals (n = 8–10). ( B ) 24 h <t>voluntary</t> <t>running</t> <t>wheel</t> <t>activity</t> of 14 wks old male mice (n = 9–10). ( C ) Skeletal muscle mRNA expression in quadriceps muscle of the myosin heavy chain ( Mhc ) fiber type markers and ( D ) mitochondrial biogenesis markers of 24 wks old animals (n = 8–10). ( E ) Representative immunoblots of PGC1α/β in quadriceps muscle from 24 wks old mice from cropped blots of the same gel using αTubulin (αTUB) as loading control (2 samples shown out of 4–5 analyzed per group). ( F ) Representative immunoblots of phospho-AMPK Thr172 and total AMPK in quadriceps muscle from 24 wks old mice from different gels processed in parallel (2 samples shown out of 4–5 analyzed per group). ( G ) Skeletal muscle (gastrocnemius) citrate synthase activity of 24 wks old animals (n = 4–8). All absolute values are expressed as box-and-whisker plots, relative or normalized data are expressed as means + SEM; ** p
    Voluntary Running Wheel Activity, supplied by TSE systems, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/voluntary running wheel activity/product/TSE systems
    Average 92 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    voluntary running wheel activity - by Bioz Stars, 2021-09
    92/100 stars

    Images

    1) Product Images from "Partial involvement of Nrf2 in skeletal muscle mitohormesis as an adaptive response to mitochondrial uncoupling"

    Article Title: Partial involvement of Nrf2 in skeletal muscle mitohormesis as an adaptive response to mitochondrial uncoupling

    Journal: Scientific Reports

    doi: 10.1038/s41598-018-20901-4

    Skeletal muscle integrity and mitochondrial biogenesis in male TG/Nrf2-Ko mice. ( A ) Grip strength of 24 wks old animals (n = 8–10). ( B ) 24 h voluntary running wheel activity of 14 wks old male mice (n = 9–10). ( C ) Skeletal muscle mRNA expression in quadriceps muscle of the myosin heavy chain ( Mhc ) fiber type markers and ( D ) mitochondrial biogenesis markers of 24 wks old animals (n = 8–10). ( E ) Representative immunoblots of PGC1α/β in quadriceps muscle from 24 wks old mice from cropped blots of the same gel using αTubulin (αTUB) as loading control (2 samples shown out of 4–5 analyzed per group). ( F ) Representative immunoblots of phospho-AMPK Thr172 and total AMPK in quadriceps muscle from 24 wks old mice from different gels processed in parallel (2 samples shown out of 4–5 analyzed per group). ( G ) Skeletal muscle (gastrocnemius) citrate synthase activity of 24 wks old animals (n = 4–8). All absolute values are expressed as box-and-whisker plots, relative or normalized data are expressed as means + SEM; ** p
    Figure Legend Snippet: Skeletal muscle integrity and mitochondrial biogenesis in male TG/Nrf2-Ko mice. ( A ) Grip strength of 24 wks old animals (n = 8–10). ( B ) 24 h voluntary running wheel activity of 14 wks old male mice (n = 9–10). ( C ) Skeletal muscle mRNA expression in quadriceps muscle of the myosin heavy chain ( Mhc ) fiber type markers and ( D ) mitochondrial biogenesis markers of 24 wks old animals (n = 8–10). ( E ) Representative immunoblots of PGC1α/β in quadriceps muscle from 24 wks old mice from cropped blots of the same gel using αTubulin (αTUB) as loading control (2 samples shown out of 4–5 analyzed per group). ( F ) Representative immunoblots of phospho-AMPK Thr172 and total AMPK in quadriceps muscle from 24 wks old mice from different gels processed in parallel (2 samples shown out of 4–5 analyzed per group). ( G ) Skeletal muscle (gastrocnemius) citrate synthase activity of 24 wks old animals (n = 4–8). All absolute values are expressed as box-and-whisker plots, relative or normalized data are expressed as means + SEM; ** p

    Techniques Used: Mouse Assay, Activity Assay, Expressing, Western Blot, Whisker Assay

    2) Product Images from "An Interval of the Obesity QTL Nob3.38 within a QTL Hotspot on Chromosome 1 Modulates Behavioral Phenotypes"

    Article Title: An Interval of the Obesity QTL Nob3.38 within a QTL Hotspot on Chromosome 1 Modulates Behavioral Phenotypes

    Journal: PLoS ONE

    doi: 10.1371/journal.pone.0053025

    Characterization of voluntary activity and the metabolism of skeletal muscle of Nob3.38 B/B and Nob3.38 N/N mice. (A) Voluntary activity of B/B and N/N mice detected with a running wheel over 24 h (n = 13). (B) Glucose uptake into isolated skeletal muscle under basal and insulin-stimulated conditions (upper panel) and palmitate oxidation (lower panel) in isolated skeletal muscle under basal and AICAR stimulated conditions (EDL, left panels; Soleus, right panels) of B/B and N/N mice. (C) Characterization of mitochondrial respiration by determination of oxygen consumption rate of isolated mitochondria from skeletal muscles of B/B and N/N mice (n = 4–6).
    Figure Legend Snippet: Characterization of voluntary activity and the metabolism of skeletal muscle of Nob3.38 B/B and Nob3.38 N/N mice. (A) Voluntary activity of B/B and N/N mice detected with a running wheel over 24 h (n = 13). (B) Glucose uptake into isolated skeletal muscle under basal and insulin-stimulated conditions (upper panel) and palmitate oxidation (lower panel) in isolated skeletal muscle under basal and AICAR stimulated conditions (EDL, left panels; Soleus, right panels) of B/B and N/N mice. (C) Characterization of mitochondrial respiration by determination of oxygen consumption rate of isolated mitochondria from skeletal muscles of B/B and N/N mice (n = 4–6).

    Techniques Used: Activity Assay, Mouse Assay, Isolation

    Characterization of the body weight and behavior of RCS-IX. (A) Body weight, (B) running wheel activity, (C) grip strength, and (D) preference on the O-Maze were compared between B/B and N/N allele carriers. (E) Spatial learning was assessed by the Morris Water Maze test and escape latency (left panel) and activity (right panel) were determined during acquisition (day 1–3) and reversal (day 4–5). For testing the subcongenic line RCS-IX 5 females of B/B and 7 females of N/N genotype were used. (#p
    Figure Legend Snippet: Characterization of the body weight and behavior of RCS-IX. (A) Body weight, (B) running wheel activity, (C) grip strength, and (D) preference on the O-Maze were compared between B/B and N/N allele carriers. (E) Spatial learning was assessed by the Morris Water Maze test and escape latency (left panel) and activity (right panel) were determined during acquisition (day 1–3) and reversal (day 4–5). For testing the subcongenic line RCS-IX 5 females of B/B and 7 females of N/N genotype were used. (#p

    Techniques Used: Activity Assay

    Related Articles

    Mouse Assay:

    Article Title: The Fat Mass and Obesity-Associated Protein (FTO) Regulates Locomotor Responses to Novelty via D2R Medium Spiny Neurons.
    Article Snippet: .. Furthermore, in independent cohorts of mice, the cages were additionally equipped with running wheels (TSE Systems) for measuring spontaneous, voluntary running. ..

    Activity Assay:

    Article Title: High-fat Diet and Physical Exercise Differentially Modulate Adult Neurogenesis in the Mouse Hypothalamus.
    Article Snippet: .. The hypothalamus has emerged as a novel neurogenic niche in the adult brain during the past decade.. However, little is known about its regulation and the role hypothalamic neurogenesis might play in body weight and appetite control. ..

    Article Title: Meis1: effects on motor phenotypes and the sensorimotor system in mice
    Article Snippet: .. In the males, this occurs in the PhenoMaster cages and, in the females, in their voluntary wheel-running activity pattern. ..

    Article Title: An Interval of the Obesity QTL Nob3.38 within a QTL Hotspot on Chromosome 1 Modulates Behavioral Phenotypes
    Article Snippet: .. Voluntary running wheel activity was recorded with an automated running wheel system (TSE). ..

    Article Title: Partial involvement of Nrf2 in skeletal muscle mitohormesis as an adaptive response to mitochondrial uncoupling
    Article Snippet: .. Voluntary running wheel activity was determined by IR motion detectors (TSE Systems GmbH, Homburg, Germany). ..

    other:

    Article Title: Evaluation of exercise-induced modulation of glial activation and dopaminergic damage in a rat model of Parkinson’s disease using [11C]PBR28 and [18F]FDOPA PET
    Article Snippet: All animals, including animals from the sedentary groups, were adapted to the motorized running wheel (TSE systems, 303400 series, 252 mm diameter) between baseline measurements and surgery by forcing them to run for 15 min on two consecutive days (6.7 m/min).

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    TSE systems voluntary running wheel activity
    Skeletal muscle integrity and mitochondrial biogenesis in male TG/Nrf2-Ko mice. ( A ) Grip strength of 24 wks old animals (n = 8–10). ( B ) 24 h <t>voluntary</t> <t>running</t> <t>wheel</t> <t>activity</t> of 14 wks old male mice (n = 9–10). ( C ) Skeletal muscle mRNA expression in quadriceps muscle of the myosin heavy chain ( Mhc ) fiber type markers and ( D ) mitochondrial biogenesis markers of 24 wks old animals (n = 8–10). ( E ) Representative immunoblots of PGC1α/β in quadriceps muscle from 24 wks old mice from cropped blots of the same gel using αTubulin (αTUB) as loading control (2 samples shown out of 4–5 analyzed per group). ( F ) Representative immunoblots of phospho-AMPK Thr172 and total AMPK in quadriceps muscle from 24 wks old mice from different gels processed in parallel (2 samples shown out of 4–5 analyzed per group). ( G ) Skeletal muscle (gastrocnemius) citrate synthase activity of 24 wks old animals (n = 4–8). All absolute values are expressed as box-and-whisker plots, relative or normalized data are expressed as means + SEM; ** p
    Voluntary Running Wheel Activity, supplied by TSE systems, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/voluntary running wheel activity/product/TSE systems
    Average 92 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    voluntary running wheel activity - by Bioz Stars, 2021-09
    92/100 stars
      Buy from Supplier

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    Skeletal muscle integrity and mitochondrial biogenesis in male TG/Nrf2-Ko mice. ( A ) Grip strength of 24 wks old animals (n = 8–10). ( B ) 24 h voluntary running wheel activity of 14 wks old male mice (n = 9–10). ( C ) Skeletal muscle mRNA expression in quadriceps muscle of the myosin heavy chain ( Mhc ) fiber type markers and ( D ) mitochondrial biogenesis markers of 24 wks old animals (n = 8–10). ( E ) Representative immunoblots of PGC1α/β in quadriceps muscle from 24 wks old mice from cropped blots of the same gel using αTubulin (αTUB) as loading control (2 samples shown out of 4–5 analyzed per group). ( F ) Representative immunoblots of phospho-AMPK Thr172 and total AMPK in quadriceps muscle from 24 wks old mice from different gels processed in parallel (2 samples shown out of 4–5 analyzed per group). ( G ) Skeletal muscle (gastrocnemius) citrate synthase activity of 24 wks old animals (n = 4–8). All absolute values are expressed as box-and-whisker plots, relative or normalized data are expressed as means + SEM; ** p

    Journal: Scientific Reports

    Article Title: Partial involvement of Nrf2 in skeletal muscle mitohormesis as an adaptive response to mitochondrial uncoupling

    doi: 10.1038/s41598-018-20901-4

    Figure Lengend Snippet: Skeletal muscle integrity and mitochondrial biogenesis in male TG/Nrf2-Ko mice. ( A ) Grip strength of 24 wks old animals (n = 8–10). ( B ) 24 h voluntary running wheel activity of 14 wks old male mice (n = 9–10). ( C ) Skeletal muscle mRNA expression in quadriceps muscle of the myosin heavy chain ( Mhc ) fiber type markers and ( D ) mitochondrial biogenesis markers of 24 wks old animals (n = 8–10). ( E ) Representative immunoblots of PGC1α/β in quadriceps muscle from 24 wks old mice from cropped blots of the same gel using αTubulin (αTUB) as loading control (2 samples shown out of 4–5 analyzed per group). ( F ) Representative immunoblots of phospho-AMPK Thr172 and total AMPK in quadriceps muscle from 24 wks old mice from different gels processed in parallel (2 samples shown out of 4–5 analyzed per group). ( G ) Skeletal muscle (gastrocnemius) citrate synthase activity of 24 wks old animals (n = 4–8). All absolute values are expressed as box-and-whisker plots, relative or normalized data are expressed as means + SEM; ** p

    Article Snippet: Voluntary running wheel activity was determined by IR motion detectors (TSE Systems GmbH, Homburg, Germany).

    Techniques: Mouse Assay, Activity Assay, Expressing, Western Blot, Whisker Assay

    Characterization of voluntary activity and the metabolism of skeletal muscle of Nob3.38 B/B and Nob3.38 N/N mice. (A) Voluntary activity of B/B and N/N mice detected with a running wheel over 24 h (n = 13). (B) Glucose uptake into isolated skeletal muscle under basal and insulin-stimulated conditions (upper panel) and palmitate oxidation (lower panel) in isolated skeletal muscle under basal and AICAR stimulated conditions (EDL, left panels; Soleus, right panels) of B/B and N/N mice. (C) Characterization of mitochondrial respiration by determination of oxygen consumption rate of isolated mitochondria from skeletal muscles of B/B and N/N mice (n = 4–6).

    Journal: PLoS ONE

    Article Title: An Interval of the Obesity QTL Nob3.38 within a QTL Hotspot on Chromosome 1 Modulates Behavioral Phenotypes

    doi: 10.1371/journal.pone.0053025

    Figure Lengend Snippet: Characterization of voluntary activity and the metabolism of skeletal muscle of Nob3.38 B/B and Nob3.38 N/N mice. (A) Voluntary activity of B/B and N/N mice detected with a running wheel over 24 h (n = 13). (B) Glucose uptake into isolated skeletal muscle under basal and insulin-stimulated conditions (upper panel) and palmitate oxidation (lower panel) in isolated skeletal muscle under basal and AICAR stimulated conditions (EDL, left panels; Soleus, right panels) of B/B and N/N mice. (C) Characterization of mitochondrial respiration by determination of oxygen consumption rate of isolated mitochondria from skeletal muscles of B/B and N/N mice (n = 4–6).

    Article Snippet: Voluntary running wheel activity was recorded with an automated running wheel system (TSE).

    Techniques: Activity Assay, Mouse Assay, Isolation

    Characterization of the body weight and behavior of RCS-IX. (A) Body weight, (B) running wheel activity, (C) grip strength, and (D) preference on the O-Maze were compared between B/B and N/N allele carriers. (E) Spatial learning was assessed by the Morris Water Maze test and escape latency (left panel) and activity (right panel) were determined during acquisition (day 1–3) and reversal (day 4–5). For testing the subcongenic line RCS-IX 5 females of B/B and 7 females of N/N genotype were used. (#p

    Journal: PLoS ONE

    Article Title: An Interval of the Obesity QTL Nob3.38 within a QTL Hotspot on Chromosome 1 Modulates Behavioral Phenotypes

    doi: 10.1371/journal.pone.0053025

    Figure Lengend Snippet: Characterization of the body weight and behavior of RCS-IX. (A) Body weight, (B) running wheel activity, (C) grip strength, and (D) preference on the O-Maze were compared between B/B and N/N allele carriers. (E) Spatial learning was assessed by the Morris Water Maze test and escape latency (left panel) and activity (right panel) were determined during acquisition (day 1–3) and reversal (day 4–5). For testing the subcongenic line RCS-IX 5 females of B/B and 7 females of N/N genotype were used. (#p

    Article Snippet: Voluntary running wheel activity was recorded with an automated running wheel system (TSE).

    Techniques: Activity Assay