mx 1 cells  (CLS Cell Lines Service GmbH)


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    CLS Cell Lines Service GmbH mx 1 cells
    The combinatory effect of eribulin (ERI) and paclitaxel (PTX) on MDA-MB-231, Hs578T, MDA-MB-157, and <t>Mx-1</t> cells was tested using WST assays. ( A ) Sensitivity to PTX in the presence or absence of low doses of ERI (upper panels for each cell line) and sensitivity to ERI in the presence or absence of low doses of PTX (lower panels for each cell line). Closed circles (●) indicate control, closed triangles (▲) indicate 0.1 nM (MDA-MB-231 and Hs578T cells) or 0.05 nM (MDA-MB-157 and Mx-1 cells) of ERI, open circles (○) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of ERI, closed squares (■) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of PTX, and open squares (□) indicate 0.3 nM (MDA-MB-157 and Mx-1 cells), 0.5 nM (MDA-MB-231 cells), or 1.0 nM (Hs578T cells) of PTX. The error bars represent the standard deviations of the values obtained; experiments were performed in triplicate. ( B ) The experimental data were plotted on an isobologram. The dots located below, on, or above the diagonal line indicate synergistic, additive, and antagonistic effects, respectively.
    Mx 1 Cells, supplied by CLS Cell Lines Service GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mx 1 cells/product/CLS Cell Lines Service GmbH
    Average 90 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    mx 1 cells - by Bioz Stars, 2024-04
    90/100 stars

    Images

    1) Product Images from "Combination of two anti-tubulin agents, eribulin and paclitaxel, enhances anti-tumor effects on triple-negative breast cancer through mesenchymal-epithelial transition"

    Article Title: Combination of two anti-tubulin agents, eribulin and paclitaxel, enhances anti-tumor effects on triple-negative breast cancer through mesenchymal-epithelial transition

    Journal: Oncotarget

    doi: 10.18632/oncotarget.25184

    The combinatory effect of eribulin (ERI) and paclitaxel (PTX) on MDA-MB-231, Hs578T, MDA-MB-157, and Mx-1 cells was tested using WST assays. ( A ) Sensitivity to PTX in the presence or absence of low doses of ERI (upper panels for each cell line) and sensitivity to ERI in the presence or absence of low doses of PTX (lower panels for each cell line). Closed circles (●) indicate control, closed triangles (▲) indicate 0.1 nM (MDA-MB-231 and Hs578T cells) or 0.05 nM (MDA-MB-157 and Mx-1 cells) of ERI, open circles (○) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of ERI, closed squares (■) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of PTX, and open squares (□) indicate 0.3 nM (MDA-MB-157 and Mx-1 cells), 0.5 nM (MDA-MB-231 cells), or 1.0 nM (Hs578T cells) of PTX. The error bars represent the standard deviations of the values obtained; experiments were performed in triplicate. ( B ) The experimental data were plotted on an isobologram. The dots located below, on, or above the diagonal line indicate synergistic, additive, and antagonistic effects, respectively.
    Figure Legend Snippet: The combinatory effect of eribulin (ERI) and paclitaxel (PTX) on MDA-MB-231, Hs578T, MDA-MB-157, and Mx-1 cells was tested using WST assays. ( A ) Sensitivity to PTX in the presence or absence of low doses of ERI (upper panels for each cell line) and sensitivity to ERI in the presence or absence of low doses of PTX (lower panels for each cell line). Closed circles (●) indicate control, closed triangles (▲) indicate 0.1 nM (MDA-MB-231 and Hs578T cells) or 0.05 nM (MDA-MB-157 and Mx-1 cells) of ERI, open circles (○) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of ERI, closed squares (■) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of PTX, and open squares (□) indicate 0.3 nM (MDA-MB-157 and Mx-1 cells), 0.5 nM (MDA-MB-231 cells), or 1.0 nM (Hs578T cells) of PTX. The error bars represent the standard deviations of the values obtained; experiments were performed in triplicate. ( B ) The experimental data were plotted on an isobologram. The dots located below, on, or above the diagonal line indicate synergistic, additive, and antagonistic effects, respectively.

    Techniques Used:

    The expression of epithelial and mesenchymal markers was studied by western blotting. Representative results of western blot analyses are shown. β-Actin was used as a loading control. The experiments were performed independently at least three times, and one representative blot is provided in the figures. ( A ) Expression of EMT markers in MDA-MB-231, Hs578T, MDA-MB-157, and Mx-1 cells treated with eribulin (ERI; 0.1 and 0.2 nM), paclitaxel (PTX; 0.5 and 1 nM), or both (ERI; 0.2 nM and PTX; 1 nM) for 96 h. ( B ) Expression of EMT markers in MDA-MB-231, Hs578T cells treated with ERI (0.2 nM) or PTX (1 nM) for 24 h and 48 h.
    Figure Legend Snippet: The expression of epithelial and mesenchymal markers was studied by western blotting. Representative results of western blot analyses are shown. β-Actin was used as a loading control. The experiments were performed independently at least three times, and one representative blot is provided in the figures. ( A ) Expression of EMT markers in MDA-MB-231, Hs578T, MDA-MB-157, and Mx-1 cells treated with eribulin (ERI; 0.1 and 0.2 nM), paclitaxel (PTX; 0.5 and 1 nM), or both (ERI; 0.2 nM and PTX; 1 nM) for 96 h. ( B ) Expression of EMT markers in MDA-MB-231, Hs578T cells treated with ERI (0.2 nM) or PTX (1 nM) for 24 h and 48 h.

    Techniques Used: Expressing, Western Blot

    mx 1 cells  (CLS Cell Lines Service GmbH)


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    CLS Cell Lines Service GmbH mx 1 cells
    The combinatory effect of eribulin (ERI) and paclitaxel (PTX) on MDA-MB-231, Hs578T, MDA-MB-157, and <t>Mx-1</t> cells was tested using WST assays. ( A ) Sensitivity to PTX in the presence or absence of low doses of ERI (upper panels for each cell line) and sensitivity to ERI in the presence or absence of low doses of PTX (lower panels for each cell line). Closed circles (●) indicate control, closed triangles (▲) indicate 0.1 nM (MDA-MB-231 and Hs578T cells) or 0.05 nM (MDA-MB-157 and Mx-1 cells) of ERI, open circles (○) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of ERI, closed squares (■) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of PTX, and open squares (□) indicate 0.3 nM (MDA-MB-157 and Mx-1 cells), 0.5 nM (MDA-MB-231 cells), or 1.0 nM (Hs578T cells) of PTX. The error bars represent the standard deviations of the values obtained; experiments were performed in triplicate. ( B ) The experimental data were plotted on an isobologram. The dots located below, on, or above the diagonal line indicate synergistic, additive, and antagonistic effects, respectively.
    Mx 1 Cells, supplied by CLS Cell Lines Service GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mx 1 cells/product/CLS Cell Lines Service GmbH
    Average 90 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    mx 1 cells - by Bioz Stars, 2024-04
    90/100 stars

    Images

    1) Product Images from "Combination of two anti-tubulin agents, eribulin and paclitaxel, enhances anti-tumor effects on triple-negative breast cancer through mesenchymal-epithelial transition"

    Article Title: Combination of two anti-tubulin agents, eribulin and paclitaxel, enhances anti-tumor effects on triple-negative breast cancer through mesenchymal-epithelial transition

    Journal: Oncotarget

    doi: 10.18632/oncotarget.25184

    The combinatory effect of eribulin (ERI) and paclitaxel (PTX) on MDA-MB-231, Hs578T, MDA-MB-157, and Mx-1 cells was tested using WST assays. ( A ) Sensitivity to PTX in the presence or absence of low doses of ERI (upper panels for each cell line) and sensitivity to ERI in the presence or absence of low doses of PTX (lower panels for each cell line). Closed circles (●) indicate control, closed triangles (▲) indicate 0.1 nM (MDA-MB-231 and Hs578T cells) or 0.05 nM (MDA-MB-157 and Mx-1 cells) of ERI, open circles (○) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of ERI, closed squares (■) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of PTX, and open squares (□) indicate 0.3 nM (MDA-MB-157 and Mx-1 cells), 0.5 nM (MDA-MB-231 cells), or 1.0 nM (Hs578T cells) of PTX. The error bars represent the standard deviations of the values obtained; experiments were performed in triplicate. ( B ) The experimental data were plotted on an isobologram. The dots located below, on, or above the diagonal line indicate synergistic, additive, and antagonistic effects, respectively.
    Figure Legend Snippet: The combinatory effect of eribulin (ERI) and paclitaxel (PTX) on MDA-MB-231, Hs578T, MDA-MB-157, and Mx-1 cells was tested using WST assays. ( A ) Sensitivity to PTX in the presence or absence of low doses of ERI (upper panels for each cell line) and sensitivity to ERI in the presence or absence of low doses of PTX (lower panels for each cell line). Closed circles (●) indicate control, closed triangles (▲) indicate 0.1 nM (MDA-MB-231 and Hs578T cells) or 0.05 nM (MDA-MB-157 and Mx-1 cells) of ERI, open circles (○) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of ERI, closed squares (■) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of PTX, and open squares (□) indicate 0.3 nM (MDA-MB-157 and Mx-1 cells), 0.5 nM (MDA-MB-231 cells), or 1.0 nM (Hs578T cells) of PTX. The error bars represent the standard deviations of the values obtained; experiments were performed in triplicate. ( B ) The experimental data were plotted on an isobologram. The dots located below, on, or above the diagonal line indicate synergistic, additive, and antagonistic effects, respectively.

    Techniques Used:

    The expression of epithelial and mesenchymal markers was studied by western blotting. Representative results of western blot analyses are shown. β-Actin was used as a loading control. The experiments were performed independently at least three times, and one representative blot is provided in the figures. ( A ) Expression of EMT markers in MDA-MB-231, Hs578T, MDA-MB-157, and Mx-1 cells treated with eribulin (ERI; 0.1 and 0.2 nM), paclitaxel (PTX; 0.5 and 1 nM), or both (ERI; 0.2 nM and PTX; 1 nM) for 96 h. ( B ) Expression of EMT markers in MDA-MB-231, Hs578T cells treated with ERI (0.2 nM) or PTX (1 nM) for 24 h and 48 h.
    Figure Legend Snippet: The expression of epithelial and mesenchymal markers was studied by western blotting. Representative results of western blot analyses are shown. β-Actin was used as a loading control. The experiments were performed independently at least three times, and one representative blot is provided in the figures. ( A ) Expression of EMT markers in MDA-MB-231, Hs578T, MDA-MB-157, and Mx-1 cells treated with eribulin (ERI; 0.1 and 0.2 nM), paclitaxel (PTX; 0.5 and 1 nM), or both (ERI; 0.2 nM and PTX; 1 nM) for 96 h. ( B ) Expression of EMT markers in MDA-MB-231, Hs578T cells treated with ERI (0.2 nM) or PTX (1 nM) for 24 h and 48 h.

    Techniques Used: Expressing, Western Blot

    mammary carcinoma xenografts  (CLS Cell Lines Service GmbH)


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    CLS Cell Lines Service GmbH mammary carcinoma xenografts
    Mammary Carcinoma Xenografts, supplied by CLS Cell Lines Service GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mammary carcinoma xenografts/product/CLS Cell Lines Service GmbH
    Average 90 stars, based on 1 article reviews
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    CLS Cell Lines Service GmbH mx 1 cells
    The combinatory effect of eribulin (ERI) and paclitaxel (PTX) on MDA-MB-231, Hs578T, MDA-MB-157, and <t>Mx-1</t> cells was tested using WST assays. ( A ) Sensitivity to PTX in the presence or absence of low doses of ERI (upper panels for each cell line) and sensitivity to ERI in the presence or absence of low doses of PTX (lower panels for each cell line). Closed circles (●) indicate control, closed triangles (▲) indicate 0.1 nM (MDA-MB-231 and Hs578T cells) or 0.05 nM (MDA-MB-157 and Mx-1 cells) of ERI, open circles (○) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of ERI, closed squares (■) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of PTX, and open squares (□) indicate 0.3 nM (MDA-MB-157 and Mx-1 cells), 0.5 nM (MDA-MB-231 cells), or 1.0 nM (Hs578T cells) of PTX. The error bars represent the standard deviations of the values obtained; experiments were performed in triplicate. ( B ) The experimental data were plotted on an isobologram. The dots located below, on, or above the diagonal line indicate synergistic, additive, and antagonistic effects, respectively.
    Mx 1 Cells, supplied by CLS Cell Lines Service GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mx 1 cells/product/CLS Cell Lines Service GmbH
    Average 90 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    mx 1 cells - by Bioz Stars, 2024-04
    90/100 stars
      Buy from Supplier

    90
    CLS Cell Lines Service GmbH mammary carcinoma xenografts
    The combinatory effect of eribulin (ERI) and paclitaxel (PTX) on MDA-MB-231, Hs578T, MDA-MB-157, and <t>Mx-1</t> cells was tested using WST assays. ( A ) Sensitivity to PTX in the presence or absence of low doses of ERI (upper panels for each cell line) and sensitivity to ERI in the presence or absence of low doses of PTX (lower panels for each cell line). Closed circles (●) indicate control, closed triangles (▲) indicate 0.1 nM (MDA-MB-231 and Hs578T cells) or 0.05 nM (MDA-MB-157 and Mx-1 cells) of ERI, open circles (○) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of ERI, closed squares (■) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of PTX, and open squares (□) indicate 0.3 nM (MDA-MB-157 and Mx-1 cells), 0.5 nM (MDA-MB-231 cells), or 1.0 nM (Hs578T cells) of PTX. The error bars represent the standard deviations of the values obtained; experiments were performed in triplicate. ( B ) The experimental data were plotted on an isobologram. The dots located below, on, or above the diagonal line indicate synergistic, additive, and antagonistic effects, respectively.
    Mammary Carcinoma Xenografts, supplied by CLS Cell Lines Service GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mammary carcinoma xenografts/product/CLS Cell Lines Service GmbH
    Average 90 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    mammary carcinoma xenografts - by Bioz Stars, 2024-04
    90/100 stars
      Buy from Supplier

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    The combinatory effect of eribulin (ERI) and paclitaxel (PTX) on MDA-MB-231, Hs578T, MDA-MB-157, and Mx-1 cells was tested using WST assays. ( A ) Sensitivity to PTX in the presence or absence of low doses of ERI (upper panels for each cell line) and sensitivity to ERI in the presence or absence of low doses of PTX (lower panels for each cell line). Closed circles (●) indicate control, closed triangles (▲) indicate 0.1 nM (MDA-MB-231 and Hs578T cells) or 0.05 nM (MDA-MB-157 and Mx-1 cells) of ERI, open circles (○) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of ERI, closed squares (■) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of PTX, and open squares (□) indicate 0.3 nM (MDA-MB-157 and Mx-1 cells), 0.5 nM (MDA-MB-231 cells), or 1.0 nM (Hs578T cells) of PTX. The error bars represent the standard deviations of the values obtained; experiments were performed in triplicate. ( B ) The experimental data were plotted on an isobologram. The dots located below, on, or above the diagonal line indicate synergistic, additive, and antagonistic effects, respectively.

    Journal: Oncotarget

    Article Title: Combination of two anti-tubulin agents, eribulin and paclitaxel, enhances anti-tumor effects on triple-negative breast cancer through mesenchymal-epithelial transition

    doi: 10.18632/oncotarget.25184

    Figure Lengend Snippet: The combinatory effect of eribulin (ERI) and paclitaxel (PTX) on MDA-MB-231, Hs578T, MDA-MB-157, and Mx-1 cells was tested using WST assays. ( A ) Sensitivity to PTX in the presence or absence of low doses of ERI (upper panels for each cell line) and sensitivity to ERI in the presence or absence of low doses of PTX (lower panels for each cell line). Closed circles (●) indicate control, closed triangles (▲) indicate 0.1 nM (MDA-MB-231 and Hs578T cells) or 0.05 nM (MDA-MB-157 and Mx-1 cells) of ERI, open circles (○) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of ERI, closed squares (■) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of PTX, and open squares (□) indicate 0.3 nM (MDA-MB-157 and Mx-1 cells), 0.5 nM (MDA-MB-231 cells), or 1.0 nM (Hs578T cells) of PTX. The error bars represent the standard deviations of the values obtained; experiments were performed in triplicate. ( B ) The experimental data were plotted on an isobologram. The dots located below, on, or above the diagonal line indicate synergistic, additive, and antagonistic effects, respectively.

    Article Snippet: Three TNBC cell lines (MDA-MB-231, Hs578T, and MDA-MB-157) were purchased from the American Type Cell Collection (Manassas, VA), and Mx-1 cells were purchased from CLS Cell Lines Service (Eppelheim, Germany) in 2016, and passaged in our laboratory for less than 6 months after receipt or resuscitation.

    Techniques:

    The expression of epithelial and mesenchymal markers was studied by western blotting. Representative results of western blot analyses are shown. β-Actin was used as a loading control. The experiments were performed independently at least three times, and one representative blot is provided in the figures. ( A ) Expression of EMT markers in MDA-MB-231, Hs578T, MDA-MB-157, and Mx-1 cells treated with eribulin (ERI; 0.1 and 0.2 nM), paclitaxel (PTX; 0.5 and 1 nM), or both (ERI; 0.2 nM and PTX; 1 nM) for 96 h. ( B ) Expression of EMT markers in MDA-MB-231, Hs578T cells treated with ERI (0.2 nM) or PTX (1 nM) for 24 h and 48 h.

    Journal: Oncotarget

    Article Title: Combination of two anti-tubulin agents, eribulin and paclitaxel, enhances anti-tumor effects on triple-negative breast cancer through mesenchymal-epithelial transition

    doi: 10.18632/oncotarget.25184

    Figure Lengend Snippet: The expression of epithelial and mesenchymal markers was studied by western blotting. Representative results of western blot analyses are shown. β-Actin was used as a loading control. The experiments were performed independently at least three times, and one representative blot is provided in the figures. ( A ) Expression of EMT markers in MDA-MB-231, Hs578T, MDA-MB-157, and Mx-1 cells treated with eribulin (ERI; 0.1 and 0.2 nM), paclitaxel (PTX; 0.5 and 1 nM), or both (ERI; 0.2 nM and PTX; 1 nM) for 96 h. ( B ) Expression of EMT markers in MDA-MB-231, Hs578T cells treated with ERI (0.2 nM) or PTX (1 nM) for 24 h and 48 h.

    Article Snippet: Three TNBC cell lines (MDA-MB-231, Hs578T, and MDA-MB-157) were purchased from the American Type Cell Collection (Manassas, VA), and Mx-1 cells were purchased from CLS Cell Lines Service (Eppelheim, Germany) in 2016, and passaged in our laboratory for less than 6 months after receipt or resuscitation.

    Techniques: Expressing, Western Blot